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  • #16
    Re: CDC Release Swine Flu Sequences in Real Time

    Originally posted by JJackson View Post
    Has anyone got a link to public accessible/downloadable sequences?

    Or, at the least, some information regarding where the GISAID sequences fit in phylogenic trees that I can compare with sequences I do have access to.

    Or failing that just some sensible comments from anyone who has seen the sequences. i.e. beyond 'they have some human, avian and swine genes' (very helpful)
    from: http://www.bbc.co.uk/blogs/newsnight...ut_potent.html

    (snipped)

    Dr Alan Hay, director of the World Influenza Centre in London....

    There are eight genes in the flu virus. According to Dr Hay, this new one has six genes from swine flu viruses already known to have been circulating in the US, and two from swine flu viruses from Europe and Asia. The US swine flu virus genes in this new virus are themselves mixtures of swine flu, bird flu and human flu viruses - what's described as a classic "re-assortment" - a combination feared most by those watching for a flu pandemic. Experts around the world have been warning for years that this is inevitable. The last pandemic was in 1968 and killed around a million people worldwide.

    .
    "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

    Comment


    • #17
      Re: CDC Release Swine Flu Sequences in Real Time

      Originally posted by SophiaZoe View Post
      Thanks GS! That helps. I assume your assumption is probably correct.
      Your assumptions are in error.

      Comment


      • #18
        Re: CDC Release Swine Flu Sequences in Real Time

        INFLUENZA A (H1N1) VIRUS, SWINE, HUMAN - NORTH AMERICA (02)
        ************************************************** *********
        A ProMED-mail post
        <http://www.promedmail.org>
        ProMED-mail is a program of the
        International Society for Infectious Diseases
        <http://www.isid.org>

        Update:
        [1] and [2] Strain identity
        [3] Pandemic warning
        [4] Outbreak in NY ?

        ******
        [1] Strain identity
        Date: Fri 24 Apr 2009
        Source: CIDRAP News [edited]
        <http://www.cidrap.umn.edu/cidrap/con...2409swine.html>


        Labs confirm same swine flu in deadly Mexican outbreaks
        -------------------------------------------------------
        Samples from a deadly respiratory illness outbreak in Mexico match swine
        influenza isolates from patients in the United States who had milder
        illnesses, an official from the US Centers for Disease Control and
        Prevention (CDC) said today [24 Apr 2009], fueling speculation that the
        World Health Organization (WHO) could be on the verge of raising the global
        pandemic alert level. Richard Besser, MD, CDC's acting director, told
        reporters today during a press teleconference that the development is
        worrisome. "Our concern has grown since yesterday, based on what we've
        learned," he said. "We do not know if this will lead to the next pandemic,
        but our scientists are monitoring it and take the threat very seriously."

        The swine flu A/H1N1 strain has been confirmed in one more US citizen, a
        child from San Diego who has recovered, raising the total number of US
        cases to 8, Besser said. The virus contains gene segments from 4 different
        influenza types: North American swine, North American avian, human, and
        Eurasian swine.

        WHO said today that Mexican officials have reported 3 separate events. In
        the Federal District, the number of cases rose steadily through April, and
        as of yesterday, more than 854 cases of pneumonia, 59 of them fatal, had
        been reported in Mexico City. The illness outbreak in Mexico City prompted
        the country's health minister, Jose Cordova, to cancel classes in Mexico
        City today and advise students and adults to avoid crowded public places
        and large events, Bloomberg News reported. Mexican officials also reported
        24 cases with 3 deaths from an influenza-like illness in San Luis Potosi,
        in the central part of the country, and 4 cases with no deaths in Mexicali,
        near the US border, WHO reported.

        The virus in Mexico has primarily struck otherwise healthy young adults,
        WHO said, which is a departure from seasonal influenza, which typically
        affects the very young and very old. CDC's laboratory analyzed 14 samples
        from severely ill Mexican patients and found that 7 of them had the same
        swine flu mix as the virus that infected the US patients. Besser called the
        analysis preliminary, however, and said that CDC doesn't yet have enough
        information to draw conclusions. "We still don't have enough information
        about the extent of the spread or the illness spectrum." WHO said today
        that Canada's national laboratory has confirmed swine flu A/H1N1 in 18
        isolates from Mexican patients, 12 of which were genetically identical to
        the swine flu viruses from California.

        WHO and CDC both said they were sending representatives to Mexico to assist
        local authorities, and WHO said it has alerted its Global Alert and
        Response Network. Besser said that WHO will likely convene an expert panel
        to discuss raising the pandemic alert level from 3 (human infection with
        new influenza subtype with only rare human-to-human spread) to 4 (small
        clusters with localized human-to-human transmission). He said the experts
        will consider 3 factors: the novelty of the virus, disease severity, and
        how easily transmission of the virus is sustained. Global health officials
        might consider a containment strategy such as dispatching antiviral
        medications to affected parts of Mexico in an attempt to stop the spread of
        the virus, but Besser said that such a measure might not work, because
        there are signs that the virus has already spread from human to human over
        long distances. "A focused, well defined area is not something we've seen
        here," he said. CDC officials have said the swine flu A/H1N1 virus is
        susceptible to the newer antivirals oseltamivir (Tamiflu) and zanamivir
        (Relenza), but not the older ones, amantadine and rimantadine. Jeff
        McLaughlin, a spokesman for GlaxoSmithKline, the maker of Relenza, told
        CIDRAP News that the company is watching the swine flu developments
        closely. Terry Hurley, a spokesman for Roche, which produces Tamiflu, said
        its "rapid response stockpile" is on 24-hour standby, as usual, for
        deployment to WHO, which has not yet requested it.

        The threat from the swine flu virus serves as a reminder for individuals
        and businesses to think about their own level of preparedness, Besser said.
        "This is a time for people to be thinking about that teachable moment." So
        far, federal officials have not changed their travel recommendations to
        California, Texas, or Mexico, though they have issued an advisory about the
        increased health risk in certain parts of Mexico, urging travelers to take
        standard precautions such hand washing, staying home when sick, and using
        good coughing and sneezing hygiene.

        [byline: Lisa Schnirring]

        --
        communicated by:
        ProMED-mail
        <promed@promedmail.org>

        [The "swine" influenza A(H1N1) virus associated with current outbreaks of
        respiratory illness in the southern region of the USA and in Mexico appears
        to be a complex reassortant containing genome components from avian, human,
        and swine virus sources. Such a virus is unique and it is too early to
        conclude that this virus has originated in swine.

        According to the CDC website (<http://www.cdc.gov/swineflu/>) swine
        influenza (swine flu) is a respiratory disease of pigs caused by type A
        influenza viruses that regularly cause outbreaks of influenza among pigs.
        Swine flu viruses do not normally infect humans; however, human infections
        with swine flu do occur, and cases of human-to-human spread of swine flu
        viruses has been documented. From December 2005 through February 2009, a
        total of 12 human infections with swine influenza were reported from 10
        states in the United States. Since March 2009, a number of confirmed human
        cases of the new strain of swine influenza A (H1N1) virus infection in
        California, Texas, and Mexico have been identified.

        Whatever the origin of the current outbreak virus it is likely that the
        designation swine influenza virus will stick. - Mod.CP]

        ******
        [2] Strain identity
        Date: Fri 24 Apr 2009
        Source: CBC News [abbreviated and edited]
        <http://www.cbc.ca/health/story/2009/...ico090424.html>


        Canadian lab confirms human swine flu cases in Mexico
        -----------------------------------------------------
        "Today we have received results which confirm that the virus is human swine
        influenza," Leona Aglukkaq told a press conference in Ottawa, Ontario,
        Canada. A handful of cases of flu-like illness in Canadian residents who
        recently returned from Mexico are being monitored; however, "there have
        been no confirmed cases of human swine influenza yet" here, said Dr David
        Butler-Jones, Canada's chief public health officer.

        Mexico sent 51 specimens for testing to Canada's National Microbiology
        Laboratory on Wednesday [21 Apr 2009]. 16 positives of swine flu were found
        among the samples. Mexican health minister Jose Angel Cordova said on
        Friday that 20 people were killed in the outbreak and 1004 were infected
        throughout the country, prompting WHO to convene an emergency meeting on
        Saturday. Officials closed schools, museums and libraries in Mexico City on
        Friday to limit spread of the virus.

        Dr Rich Besser, acting head of the US Centers for Disease Control (CDC),
        said early analysis of Mexican samples of the virus showed it is very
        similar to those responsible for 8 American cases, one confirmed on Friday.
        All the US victims have recovered. Canada is working with Mexican and US
        health officials to confirm that the virus in both countries is linked and
        is in fact a new strain of influenza A H1N1 human swine virus, he added.

        "This is an interesting virus. It's a brand new virus, not only to humans
        but to the world," said Dr Frank Plummer, scientific director of the
        Winnipeg lab. "About 80 per cent of the virus is highly related to a North
        American body [?] of swine flu that's been around for a number of years,
        but about 20 per cent of it comes from an Eurasian variety of swine flu 1st
        seen in Thailand, so it's recombined [re-assorted ?] to create something
        totally new. How it did that, where it did it, when it did it, I don't
        think we know yet."

        CDC said the current strain of swine flu includes genetic material from 4
        sources: North American swine influenza viruses, North American avian
        influenza viruses, human influenza virus, and swine influenza viruses found
        in Asia and Europe -- a new combination that has not been recognized
        anywhere in the world before. There appears to be human-to-human spread in
        both the US and Mexico over a wide geographic area at this point, but
        investigators are still checking for direct contact with swine.

        WHO spokesperson Gregory Hartl said the agency needs to determine whether
        the outbreaks constitute an international public health threat. Hartl also
        said 12 of 18 samples taken from victims in Mexico showed the virus had a
        genetic structure identical to that of the virus found in California
        earlier this week. But he said the agency needs more information before it
        changes its pandemic alert level, which currently stands at 3 on a scale of
        one to 6. The virus was 1st reported earlier this week as US health
        officials scrambled to deal with the diagnoses of 7 people with the
        never-before-seen strain in Texas and California. The states share a border
        with Mexico not far from a town where 2 deaths were reported.

        Hartl said health officials are dealing with 3 separate events in Mexico,
        with most of the cases in and around the capital, Mexico City. Most of the
        cases have occurred in healthy young adults, he added. "Because these cases
        are not happening in the very old or the very young, which is normal with
        seasonal influenza, this is an unusual event and a cause for heightened
        concern," Hartl said in an interview from WHO headquarters in Geneva. It is
        also rare to see such high flu activity so late in the season, he said.
        "The end of April, especially in a place like Mexico, you would think that
        we would see quite a steep decline," said Hartl.

        On Thursday [23 Apr 2009], Canadian health officials issued advice warning
        travellers who have recently returned from Mexico to be on alert for
        flu-like symptoms that could be connected to the illness.

        --
        communicated by:
        Steven McAuley
        Medical student
        University of Otago
        Dunedin, New Zealand
        <sbmcauley@gmail.com>

        ******
        [3] Pandemic warning
        Date: Sat 25 Apr 2009
        Source: MSNBC [edited]
        <http://www.msnbc.msn.com/id/30398682>


        Health officials prepare for swine flu "pandemic"
        -------------------------------------------------
        A new swine flu strain that has killed as many as 68 people and sickened
        more than 1000 across Mexico has "pandemic potential," the WHO chief said
        on Saturday [25 Apr 2009], and it may be too late to contain the sudden
        outbreak. CDC has stepped up surveillance across the United States. "We are
        worried," said CDC's Dr Anne Schuchat. "We don't think we can contain the
        spread of this virus," said Schuchat, interim deputy director for the
        Science and Public Health Program. "We are likely to find it in many other
        places." Because cases have been detected in California, Texas, and in
        several sites in Mexico, officials now must work to detect infections and
        reduce their severity, if possible. "It's time to prepare, time to think
        ahead and to be prepared for some uncertainty," she told reporters in a
        telephone briefing on Saturday.

        Two dozen new suspected cases were reported Saturday [25 Apr 2009] in
        Mexico City alone. Schools were closed and all public events suspended in
        the capital until further notice -- including more than 500 concerts and
        other gatherings in the metropolis of 20 million. A hot line fielded 2366
        calls in its 1st hours from frightened city residents who suspected they
        might have the disease. Soldiers and health workers handed out masks at
        subway stops, and hospitals dealt with crowds of people seeking help.

        WHO's director-general, Margaret Chan, said the outbreak of the
        never-before-seen virus is a very serious situation and has "pandemic
        potential". But she said it is still too early to tell if it would become a
        pandemic. "The situation is evolving quickly," Chan said in a telephone
        news conference in Geneva. "A new disease is by definition poorly
        understood. "This virus is a mix of human, pig, and bird strains that
        prompted the WHO to meet Saturday to consider declaring an international
        public health emergency -- a step that could lead to travel advisories,
        trade restrictions and border closures. Spokesman Gregory Hartl said a
        decision would not be made on Saturday.

        Scientists have warned for years about the potential for a pandemic from
        viruses that mix genetic material from humans and animals. Another reason
        to worry is that authorities said the dead so far don't include vulnerable
        infants and elderly. The Spanish flu pandemic, which killed at least 40
        million people worldwide in 1918-19, also 1st struck otherwise healthy
        young adults. This swine flu and regular flu can have similar symptoms --
        mostly fever, cough, and sore throat, though some of the US victims who
        recovered also experienced vomiting and diarrhea. But unlike with regular
        flu, humans don't have natural immunity to a virus that includes animal
        genes -- and new vaccines can take months to bring into use.

        But experts at WHO and CDC say the nature of this outbreak may make
        containment impossible. Already, more than 1000 people have been infected
        in as many as 14 of Mexico's 32 states, according to daily newspaper El
        Universal. Tests show 20 people have died of the swine flu, and 48 other
        deaths were probably due to the same strain.

        CDC and Canadian health officials were studying samples sent from Mexico,
        and airports around the world were screening passengers from Mexico for
        symptoms of the new flu strain, saying they may quarantine passengers. But
        CDC officials dismissed the idea of trying that in the United States. They
        noted there had been no direct contact between the cases in the San Diego
        and San Antonio areas, suggesting the virus had already spread from one
        geographic area through other undiagnosed people. "Anything that would be
        about containing it right now would purely be a political move," said
        Michael Osterholm, a University of Minnesota pandemic expert.

        Mexican President Felipe Calderon said his government only discovered the
        nature of the virus late on Thursday, with the help of international
        laboratories. "We are doing everything necessary," he said in a brief
        statement. But the government had said for days that its growing flu
        caseload was nothing unusual, so the sudden turnaround angered many who
        wonder if Mexico missed an opportunity to contain the outbreak.

        Across Mexico's capital, residents reacted with fatalism and confusion,
        anger, and mounting fear at the idea that their city may be ground zero for
        a global epidemic. Authorities urged people to stay home if they feel sick
        and to avoid shaking hands or kissing people on the cheeks.

        --
        communicated by:
        Charles H Calisher, PhD
        Professor, Arthropod-borne and Infectious Diseases Laboratory
        Department of Microbiology, Immunology and Pathology
        3195 Rampart Rd, Delivery Code 1690, Foothills Campus
        Fort Collins, CO 80523-1690
        College of Veterinary Medicine and Biomedical Sciences
        Colorado State University
        <calisher@cybersafe.net>

        ******
        [4] Suspected outbreak in New York
        Date: Fri 24 Apr 2009
        Source: WCBS TV News [edited]
        <http://wcbstv.com/health/swine.flu.nyc.2.994071.html>


        Possible swine flu outbreak at NYC prep school
        ----------------------------------------------
        New York City health officials say that about 75 students at a Queens high
        school have fallen ill with flu-like symptoms and testing is under way to
        rule out the strain of swine flu that has killed dozens in Mexico. The
        Health Department's Dr Don Weiss said on Friday [24 Apr 2009] that a team
        of agency doctors and investigators were dispatched to the private St
        Francis Preparatory School the previous day after students reported fever,
        sore throat, cough, aches, and pains. No one has been hospitalized.

        The handful of sick students who remained at the school were tested for a
        variety of flu strains. If they're found to have a known human strain that
        would rule out swine flu. Results could take several days. In the meantime,
        the school says it's postponing an evening event and sanitizing the
        building over the weekend.

        Mexican authorities said 60 people may have died from a swine flu virus in
        Mexico, and world health officials worry it could unleash a global flu
        epidemic. Mexico City closed schools, museums, libraries, and state-run
        theaters across the metropolis on Friday in hopes of containing the
        outbreak that has sickened more than 900. The US Centers for Disease
        Control and Prevention (CDC) said tests show some of the Mexico victims
        died from the same new strain of swine flu that sickened 8 people in Texas
        and California. It's a frightening new strain that combines genetic
        material from pigs, birds and humans.

        WHO was looking closely at the 60 deaths -- most of them in or near
        Mexico's capital. It wasn't yet clear what flu they died from, but
        spokesman Thomas Abraham said "We are very, very concerned. We have what
        appears to be a novel virus and it has spread from human to human," he
        said. "It's all hands on deck at the moment."

        WHO raised its internal alert system on Friday, preparing to divert more
        money and personnel to dealing with the outbreak. President Felipe Calderon
        cancelled a trip and met with his Cabinet to coordinate Mexico's response.
        The government has 500 000 flu vaccines and planned to administer them to
        health workers, the highest risk group. There are no vaccines available for
        the general public in Mexico, and authorities urged people to avoid
        hospitals unless they had a medical emergency, since hospitals are centers
        of infection. Some Mexican residents have started wearing blue surgical
        masks for extra protection, reports CBS News correspondent Adrienne Bard.
        The federal health minister has warned people not to go near anyone with a
        respiratory infection and to avoid kissing -- a traditional Mexican greeting.

        --
        communicated by:
        ProMED-mail rapporteur Mary Marshall

        [If infection by the novel swine flu virus is confirmed, it will represent
        a dramatic extension of the range of the outbreak virus from the southern
        states and Mexico to the north east of the United States. There is no
        reason to conclude at present, however, that this is anything other than an
        outbreak of seasonal influenza virus infection (or for that matter another
        common respiratory virus). - Mod.CP]

        [see also:
        Influenza A (H1N1) virus, swine, human - N America 20090425.1552
        Acute respiratory disease - Mexico, swine virus susp 20090424.1546
        Influenza A (H1N1) virus, swine, human - USA (02): (CA, TX) 20090424.1541
        Influenza A (H1N1) virus, swine, human - USA: (CA) 20090422.1516
        Influenza A (H1N1) virus, swine, human - Spain 20090220.0715
        2008
        ---
        Influenza A (H1N1) virus, swine, human - USA (TX) 20081125.3715
        2007
        ---
        Influenza A (H2N3) virus, swine - USA 20071219.4079
        2006
        ---
        Influenza, swine, human - USA (IA): November 2006 20070108.0077]

        ....................cp/ejp/sh

        </pre>

        Comment


        • #19
          Re: CDC Release Swine Flu Sequences in Real Time

          Originally posted by JJackson View Post
          Has anyone got a link to public accessible/downloadable sequences?

          Or, at the least, some information regarding where the GISAID sequences fit in phylogenic trees that I can compare with sequences I do have access to.

          Or failing that just some sensible comments from anyone who has seen the sequences. i.e. beyond 'they have some human, avian and swine genes' (very helpful)
          I posted this previously, but possibly on another board.

          PB2 Avian North America
          PB1 Human circa 1993
          PA Swine Eurasia +/-
          HA Swine North America
          NP Swine Eurasia +/-
          NA Swine Eurasia
          MP Swine Eurasia
          NS Swine Eurasia +/-

          Comment


          • #20
            Re: CDC Release Swine Flu Sequences in Real Time

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            gb|EU798921.1| Influenza A virus (A/swine/Korea/JL01/2005(H1N... 3608 0.0
            gb|DQ923521.1| Influenza A virus (A/swine/Korea/CN22/2006(H3N... 3608 0.0
            gb|CY004960.1| Influenza A virus (A/blue-winged teal/Alberta/... 3608 0.0
            gb|EU798923.1| Influenza A virus (A/swine/Korea/JL04/2005(H1N... 3602 0.0
            gb|EU604691.1| Influenza A virus (A/swine/OH/511445/2007(H1N1... 3599 0.0
            gb|EU871875.1| Influenza A virus (A/mallard/MN/158/2000(H3N9)... 3599 0.0
            gb|EU743559.1| Influenza A virus (A/mallard/MN/515/2000(H3N6)... 3599 0.0
            gb|CY015491.1| Influenza A virus (A/mallard/Ohio/170/1999(H6N... 3593 0.0
            gb|FJ461607.1| Influenza A virus (A/swine/Korea/C13/2008(H5N2... 3589 0.0
            gb|FJ517309.1| Influenza A virus (A/mallard/Minnesota/192/199... 3589 0.0
            gb|EU409958.1| Influenza A virus (A/swine/Ohio/C62006/06(H1N1... 3589 0.0
            gb|EU399758.1| Influenza A virus (A/Ontario/1252/2007(H3N2)) ... 3589 0.0
            gb|DQ145540.1| Influenza A virus (A/swine/Minnesota/00395/200... 3584 0.0
            gb|EU743535.1| Influenza A virus (A/mallard/MN/280/1999(H3N5)... 3580 0.0
            gb|CY013870.1| Influenza A virus (A/green-winged teal/Ohio/17... 3580 0.0
            gb|CY013262.1| Influenza A virus (A/pintail/Ohio/226/1998(H6N... 3580 0.0
            gb|CY035439.1| Influenza A virus (A/swine/Minnesota/SG-00242/... 3577 0.0
            gb|CY035414.1| Influenza A virus (A/swine/Minnesota/SG-00234/... 3577 0.0
            gb|FJ686753.1| Influenza A virus (A/mallard/Maryland/226/2001... 3575 0.0
            gb|FJ686761.1| Influenza A virus (A/mallard/Maryland/228/2001... 3575 0.0
            gb|FJ686793.1| Influenza A virus (A/mallard/Maryland/234/2001... 3575 0.0
            gb|EU258942.1| Influenza A virus (A/swine/Missouri/2124514/20... 3575 0.0
            gb|CY020876.1| Influenza A virus (A/mallard/Ohio/217/1998(H6N... 3575 0.0
            gb|AY703829.1| Influenza A virus (A/guillemot/Sweden/3/00(H6N... 3575 0.0
            gb|EU409946.1| Influenza A virus (A/swine/Ohio/24366/07(H1N1)... 3573 0.0
            gb|FJ686769.1| Influenza A virus (A/mallard/Maryland/231/2001... 3571 0.0
            gb|FJ686785.1| Influenza A virus (A/mallard/Maryland/233/2001... 3571 0.0
            gb|CY035417.1| Influenza A virus (A/swine/Minnesota/SG-00235/... 3571 0.0
            gb|CY018006.1| Influenza A virus (A/blue-winged teal/Ohio/31/... 3571 0.0
            gb|CY035433.1| Influenza A virus (A/swine/Minnesota/SG-00240/... 3568 0.0
            gb|CY035423.1| Influenza A virus (A/swine/Minnesota/SG-00237/... 3568 0.0
            gb|EU258950.1| Influenza A virus (A/swine/Missouri/4296424/20... 3566 0.0
            gb|CY005317.1| Influenza A virus (A/mallard/ALB/126/1991(H11N... 3566 0.0
            gb|CY020964.1| Influenza A virus (A/mallard/Ohio/242/1998(H6N... 3562 0.0
            gb|CY016195.1| Influenza A virus (A/mallard/Ohio/322/1998(H7N... 3562 0.0
            gb|CY035436.1| Influenza A virus (A/swine/Minnesota/SG-00241/... 3559 0.0
            gb|CY035445.1| Influenza A virus (A/swine/Illinois/SG-00244/2... 3557 0.0
            gb|CY020956.1| Influenza A virus (A/mallard/Ohio/209/1998(H11... 3557 0.0
            gb|CY035430.1| Influenza A virus (A/swine/Minnesota/SG-00239/... 3555 0.0
            gb|FJ686777.1| Influenza A virus (A/mallard/Maryland/232/2001... 3553 0.0
            gb|CY017708.1| Influenza A virus (A/mallard/Ohio/324/1988(H4N... 3553 0.0
            gb|CY004896.1| Influenza A virus (A/blue-winged teal/ALB/103/... 3553 0.0
            </pre>

            Comment


            • #21
              Re: CDC Release Swine Flu Sequences in Real Time

              Originally posted by niman View Post
              I posted this previously, but possibly on another board.

              PB2 Avian North America
              PB1 Human circa 1993
              PA Swine Eurasia +/-
              HA Swine North America
              NP Swine Eurasia +/-
              NA Swine Eurasia
              MP Swine Eurasia
              NS Swine Eurasia +/-
              Dr. Hay (post #16 above) shows different origins. Why the differences?

              .
              "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

              Comment


              • #22
                Re: CDC Release Swine Flu Sequences in Real Time

                Originally posted by AlaskaDenise View Post
                Dr. Hay (post #16 above) shows different origins. Why the differences?

                .
                Ask Dr Hay what he's reading.

                Comment


                • #23
                  Re: CDC Release Swine Flu Sequences in Real Time

                  Niman,
                  Are you a registered member at GISAID?
                  The salvage of human life ought to be placed above barter and exchange ~ Louis Harris, 1918

                  Comment


                  • #24
                    Re: CDC Release Swine Flu Sequences in Real Time

                    Thank you Dr. Niman. Exactly what I wanted.
                    What does the +/- signify?
                    I hesitate to ask but, if and when you have time, the near matches for the other strand would be wonderful.
                    And can we look forward to a commentry? No pressure - lol.

                    Comment


                    • #25
                      Re: CDC Release Swine Flu Sequences in Real Time

                      Originally posted by JJackson View Post
                      Thank you Dr. Niman. Exactly what I wanted.
                      What does the +/- signify?
                      I hesitate to ask but, if and when you have time, the near matches for the other strand would be wonderful.
                      And can we look forward to a commentry?
                      +/- means the association just leans that way (there are North American and Eurasian isolates with similar sequences).

                      Comment


                      • #26
                        Re: CDC Release Swine Flu Sequences in Real Time

                        I posted this previously, but possibly on another board.

                        PB2 Avian North America
                        PB1 Human circa 1993
                        PA Swine Eurasia +/-
                        HA Swine North America
                        NP Swine Eurasia +/-
                        NA Swine Eurasia
                        MP Swine Eurasia
                        NS Swine Eurasia +/-
                        Would you be willing to provide the name of the other board to watch for your information? Thank you.

                        Comment


                        • #27
                          Re: CDC Release Swine Flu Sequences in Real Time

                          Originally posted by gjs47 View Post
                          Would you be willing to provide the name of the other board to watch for your information? Thank you.
                          http://www.singtomeohmuse.com/viewtopic.php?t=3232

                          Comment


                          • #28
                            Re: CDC Release Swine Flu Sequences in Real Time

                            I've heard that the sequences will be probably available
                            today or tomorrow at genbank
                            I'm interested in expert panflu damage estimates
                            my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

                            Comment


                            • #29
                              Re: CDC Release Swine Flu Sequences in Real Time

                              Originally posted by niman View Post
                              Your assumptions are in error.
                              <chuckle> Rest assured... it's not the first time.

                              It doesn't change the fact that I was [and am] grateful to GS for sincerely addressing my hail for information with what was his "best available information". He did so clearly identifying it as assumption based on aged data.

                              Comment


                              • #30
                                Re: CDC Release Swine Flu Sequences in Real Time

                                Originally posted by niman View Post
                                I posted this previously, but possibly on another board.

                                ..........
                                NS Swine Eurasia +/-
                                Any signs of NS1/92 mutation?

                                .
                                "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

                                Comment

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