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  • #16
    Originally posted by Emily View Post
    GardenSpider, the only experience I have with ITP after vaccination (rabies) was in a toy breed rescue dog that also was the only dog I had to have had a microchip. The other toy breed dog I had got mast cell cancer in his rabies vaccine site, but as horrible as that was and the cancers that killed two other dogs of mine, cancer was easier to deal with than the pure autoimmune disease.

    I wonder if your friend had something that was activating his/her immune system prior to the vaccine. I wish we knew more about pinpointing risk factors for triggering autoimmunity because that would help us avoid this outcome after both vaccinations and natural infections.
    Emily, Do you know what time of cancer the toy breed had that was associated with the ITP? I wonder if anyone in the community here has some suggestions. Our friend is desperate for help. Her platelets have now dropped back down and are at 35 from the 100 they were up to on the medication. (Initially they had dropped to 10 after vaccination from the normal 350). Her doctors don't have any answers. And they don't know where to begin as to what to screen for regarding cancer. Any and all thoughts and suggestions are welcome.

    Comment


    • Emily
      Emily commented
      Editing a comment
      GardenSpider, I apologize for my post about the dogs being confusing. The dog that had ITP, (chihuahua mix), did not have cancer. We did a tick-borne illness panel that was negative. The veterinarian did not mention looking for cancer. The ITP was a mystery and very severe and sudden. His last vaccine was about 2 months prior to this. The previous owner's vet gave him a rabies vaccine the same day as prednisone for a skin allergy and a topical flea treatment. That sounded like poor practice to me. His skin was still an itchy, weeping mess when I rescued him.
      Frustrating thing is he seemed to be getting better when he just collapsed screaming one day. We rushed him to the hospital and they found he was bleeding into his skin when they touched him. He was treated with one vincristine infusion and high dose tapering prednisalone.
      So I hope that sets your friend's mind at ease if my post was behind her concerns about cancer. I actually was wondering about my dog's microchip setting him up for his reaction. Sometimes they move or crush and cause irritation. The vets did not think that could be a factor.

  • #17
    Hi Emily and larger FT community. Thank you for your input.

    Here is the redacted letter from my friends doctors regarding her condition of ITP (Idiopathic Thrombocytopinic Purpura) weeks after getting the second AstraZenca vaccine. Any ideas, thoughts are most welcome as she has taken a turn for the worse. Thank you,
    Attached Files

    Comment


    • Emily
      Emily commented
      Editing a comment
      I'm not a doctor but my understanding from dogs is that those numbers look like classic primary immune-mediated thrombocyotpenia. The platelet count was also extremely low in my dog that had ITP but other counts were fine. I had another dog that had thrompcytopenia secondary to a tick disease. He had a terrifying nose bleed, but no bruising all over his body or pain. No immune suppressing meds were needed, just antibiotic treatment.
      The article Kiwi found about the Vit D looks really hopeful if the prednisone does not work, maybe a test to run either way. Your friend looks like she had good care since a hematologist was consulted. They are the best on this.

    • GardenSpider
      GardenSpider commented
      Editing a comment
      Thank you.

  • #18
    This paper suggests its an immune response to platelets underlying the problem. Worth forwarding to her doctors?

    Thrombocytopenia and Intracranial Venous Sinus Thrombosis after “COVID-19 Vaccine AstraZeneca” Exposure

    https://www.mdpi.com/2077-0383/10/8/1599

    Comment


    • GardenSpider
      GardenSpider commented
      Editing a comment
      Thank you Vibrant62. I will forward this to my friend right away so she can share it.

  • #19
    Originally posted by GardenSpider View Post
    Hi Emily and larger FT community. Thank you for your input.

    Here is the redacted letter from my friends doctors regarding her condition of ITP (Idiopathic Thrombocytopinic Purpura) weeks after getting the second AstraZenca vaccine. Any ideas, thoughts are most welcome as she has taken a turn for the worse. Thank you,
    There is this document - which also shows possible treatments. https://www.bmj.com/content/373/bmj.n954 I hope it is of use. I am very sorry to hear about your friends illness.
    “The only security we have is our ability to adapt."

    Comment


    • #20
      https://pubmed.ncbi.nlm.nih.gov/2355...une%20diseases.

      Conclusions: In our two case reports, we found an association between vitamin D deficiency and immune thrombocytopenia where platelet levels responded to vitamin D treatment and hydroxychloroquine but not to prednisone. We believe there may be synergism between vitamin D supplementation and hydroxychloroquine. The mechanism by which high-dose vitamin D results in increased platelet counts in immune thrombocytopenia patients is unknown. However, vitamin D has long been thought to play an immunomodulatory role, which may include a dampened immune response in patients with immune thrombocytopenia or other autoimmune diseases.

      https://library.ehaweb.org/eha/2018/...html?f=media=1

      In our practice we have observed a number of patients with immune thrombocytopenia (ITP) whose platelet count has increased after vitamin D replacement...
      Last edited by kiwibird; May 1, 2021, 07:13 AM. Reason: added another link
      “The only security we have is our ability to adapt."

      Comment


      • Vibrant62
        Vibrant62 commented
        Editing a comment
        Good find, and must be worth a try in these patients. This also suggests (to me) that ensuring a high level of vitamin D may be a good precaution prior to vaccination. I hope they look into this in greater detail. I wonder if similar mechanisms are at play here with respect to the observed reductions in risk of serious disease with high levels of vitamin D and supplementation. If so it adds further evidence that the observed associations also has causation, especially if these clotting and coagulation effects are a direct consequence of something within the spike protein itself - and if this is the case, all the vaccines could have similar potential to produce this sort of side effect, although it does seem more pronounced in the adenovirus vectored vaccines, or at least the AZ one (so far)

      • Emily
        Emily commented
        Editing a comment
        Excellent find, Kiwi! Very hopeful.

    • #21
      Hi again FT community. Thank you for all of your support regarding our friend with vaccine induced ITP. She has sent the links your gave to her doctors to discuss additional treatment. She is still suffering a lot with more bruising all over her legs and persistently low platelets. Our other friend who is suffering from the opposite problem has blood clots. She has a daily doctor visit and is also having a tough time, but her doctors say her prognosis is good. But she wouldn't tell us if it wasn't.

      Now I have a third friend, my 83 year old aunt actually, who a little more that a month after getting the Moderna vaccine recently had a blood test that came back positive for diabetes. (They don't yet know what type). My aunt is not a diabetic. She doesn't smoke and is underweight if anything. She walks 10,000 steps a day religiosity, eats well, and is in good shape. We are wondering if there is any corollary between receiving the CoVid vaccine and diabetes. My aunt reported a big jump in her numbers after receiving the 2nd vaccine. I have read that people can become diabetic after having had the disease CoVid, so we are asking the question regarding the vaccine. https://www.washingtonpost.com/healt...nset-diabetes/

      Hemoglobin A1c 8.0%
      standard range 4.3%-5.6%
      3/27/19 5.4%
      2/28/18 5.3%

      Alanine transaminase 10
      standard range 10-61

      Potassium, serum 5.2
      standard range 3.5-4.5

      Glucose, fasting 108 mg
      standard range 70-99 mg

      Thoughts anyone? Or is this just a coincidence? Thank you, GS

      Comment


      • kiwibird
        kiwibird commented
        Editing a comment
        https://flutrackers.com/forum/forum/...int#post909272
        ".... these figures show 85% of people suffering some long term effects - including 4% developing Type 1 diabetes, 3% suffering a stroke, 1% developing myocarditis and 1% suffering renal failure. "

        Is it possible that your aunt had some unknown contact with someone who had covid?

      • GardenSpider
        GardenSpider commented
        Editing a comment
        I will forward your comment and ask. Thank you.

    • #22
      The paper below shows that it is indeed the spike protein itself that is causing much of the observed coagulopathy , so there are going to be problems to a greater or lesser extent with any vaccine that includes the spike protein. Of particular note is that the study authors were able to resolve underlying pathological changes in the test animals with N Acetyl Cysteine, a common supplement. Another one to forward to your friends doctors perhaps?

      SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091897/

      As the paper shows, the spike protein exerts its effects and triggers oxidative stress, which is a common causative factor in the development of diabetes. I would be surprised if vaccination would be enough in and of itself to cause the effects seen in your elderly friend. What is more likely is that this problem would have already been brewing, and could (theoretically) have been mildly exacerbated by a vaccine. I am fairly certain that an actual infection would have produced much more pronounced effects IMHO. However, a properly conducted study would be needed to examine this question for anyone to be able to answer definitively - for now it is all guesswork.

      Comment


      • #23
        bump this

        Comment


        • #24
          Originally posted by Vibrant62 View Post
          The paper below shows that it is indeed the spike protein itself that is causing much of the observed coagulopathy , so there are going to be problems to a greater or lesser extent with any vaccine that includes the spike protein. Of particular note is that the study authors were able to resolve underlying pathological changes in the test animals with N Acetyl Cysteine, a common supplement. Another one to forward to your friends doctors perhaps?

          SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2

          https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091897/

          As the paper shows, the spike protein exerts its effects and triggers oxidative stress, which is a common causative factor in the development of diabetes. I would be surprised if vaccination would be enough in and of itself to cause the effects seen in your elderly friend. What is more likely is that this problem would have already been brewing, and could (theoretically) have been mildly exacerbated by a vaccine. I am fairly certain that an actual infection would have produced much more pronounced effects IMHO. However, a properly conducted study would be needed to examine this question for anyone to be able to answer definitively - for now it is all guesswork.
          Thank you. I will forward this right away.

          Comment


          • #25
            Originally posted by sharon sanders View Post
            bump this
            Hi Sharon. I notice you have this posted on several threads and I am wondering what it means. Thanks in advance for the explanation.

            Comment


            • longshots
              longshots commented
              Editing a comment
              "bump this" --- it is basically a post in order boost the topic back to the top of the LATEST POSTS...

          • #26
            I post that to bump up to the top recent threads that have been pushed down while tetano updates the scientific library.

            A bump is not an endorsement of anything.

            Comment


            • #27
              http://www.pdsa.org/images/stories/p..._itp122010.pdf
              There are some cases where ITP has been preceded by an immunization, such as for chicken pox. If your child had a bad reaction with the one vaccine, it is possible she may also have reactions to other vaccines. No one can say for sure. According to our pediatric medical advisor, overall the rate of significant immune thrombocytopenia after MMR vaccine is very low, just slightly above the rate of childhood ITP in the general population. He routinely continues with vaccination if the child has ITP that is clinically stable. If the situation arises where the vaccinations have been postponed because of acute ITP, then he routinely does “catchup” after the ITP is resolved. He has not experienced a “relapse of ITP” in hundreds of children.
              ....
              Q I have ITP and wonder whether I should get vaccines, such as the annual flu vaccine? A Vaccines are a difficult decision for people with ITP. When we ask the medical advisors they usually recommend vaccines. However, here at PDSA we’ve heard from some people who had received various vaccines and reported that their platelets have dropped and they have gone out of remission. PDSA’s suggestion is to weigh the risks of the disease (in this case, some chance of getting the flu and dropping the platelet count because of the flu) and the possible risk of problems that might result from the vaccine. To help in your decision, you should discuss your concerns with your hematologist. You may find additional information about vaccines at the National Vaccine Information Center, at their Web site www.nvic.org and from the US Food and Drug Administration (FDA) vaccine information Web page at http://www.fda.gov/BiologicsBloodVaccines/default.htm.
              https://pdsa.org/about-itp/early-det...revention.html

              Prevention

              The Power of a Healthy Diet and Lifestyle
              “The only security we have is our ability to adapt."

              Comment


              • #28
                The friend of our who developed ITP after the AstraZeneca vaccine is in very bad shape. The medicines are not really working and her platelet count is back down to about 8. She says the doctors are not being pro-active in trying to find solutions and she worries that with such a low platelet count, she could bleed internally at any time. Anything below 10, is considered dangerous. 150 to 250 is normal. She is looking for another hematologist in London for a second opinion. Preferably someone who has taken an interest in the blood disorders provoked by the vaccine.

                Comment


                • #29
                  https://www.bitchute.com/video/trqA5NExRbrc/
                  DOCTORS TESTIFY BEFORE TEXAS STATE SENATE TO OPPOSE MANDATORY COVID SHOTS

                  Discusses protecting the rights of individuals who are opposed to taking the vaccine. The present the number of deaths reported to VAERS.
                  Doctors testify about adverse side effects they have encountered in their practices. They also discuss other successful therapies in dealing with CoVid 19.

                  Comment

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