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Treyfish's multiple zoonotics during COVID-19 pandemic thread

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  • Treyfish's multiple zoonotics during COVID-19 pandemic thread

    This is where I will keep my posts on the possible mixing of covid-19 and ebola. My thread on SARS-2 and pigs came out to be true. Many early reports said it wasn't possible, so I'm sure to see the same here before it happens in my opinion.
    Even though both diseases were present before, variants and plague and other diseases make for countless mixing opportunities. "Disease X" may be the result and some of those reports will also go here.
    Please post or comment on your findings or feelings on the matter here.
    Before long some border will be shut.
    This is not something I want, but I have to leave the door open to the possibility... and the trouble it would bring.
    I see a ton of stories out there and my strange ones will go here. So without further ado

    WHO assesses the possibility of Ebola's impact on COVID-19

    The South African COVID-19 mutation has not yet been identified in Guinea, and Ebola hemorrhagic fever is unlikely to lead to new mutations of the coronavirus, the head of the WHO Head of Office and Representative in Guinea, Georges Ki-Zerbo, told RIA Novosti...

  • #2
    Doctor who discovered Ebola warns of new deadly diseases

    December 23, 2020
    Humanity faces an unknown number of new and potentially fatal viruses emerging from Africa's tropical rainforests, according to Professor Jean-Jacques Tamfum, who helped discover the Ebola virus in 1976.

    There is a vaccine and a treatment for Ebola, which have brought down the rate at which it kills.

    But the question at the back of everyone's mind is: What if this woman doesn't have Ebola? What if, instead, she is patient zero of "Disease X," the first known infection of a new pathogen that could sweep the world as fast as COVID-19, but one that has Ebola's 50% to 90% fatality rate?

    This isn't the stuff of science fiction. It's a scientific fear, based on scientific facts.

    "We've all got to be frightened," the patient's physician, Dr. Dadin Bonkole, said. "Ebola was unknown. COVID was unknown. We have to be afraid of new diseases."

    Humanity faces an unknown number of new and potentially fatal viruses emerging from Africa's tropical rainforests, according to Professor Jean-Jacques Muyembe Tamfum, who helped discover the Ebola virus in 1976 and has been on the frontline of the hunt for new pathogens ever since....In Ingende, the fears of encountering a new, deadly, virus remained very real even after the recovery of the patient showing symptoms that looked like Ebola. Her samples were tested on site and sent on to the Congo's National Institute of Biomedical Research (INRB) in Kinshasa, where they were further tested for other diseases with similar symptoms.

    All came back negative, the illness that affected her remains a mystery...."We get cases which look very much like Ebola, but then when we do the tests, they are negative," said the head of medical services in Ingende, Dr. Christian Bompalanga.....


    • #3
      Nipah virus warning: Brain-swelling sickness with 75% death rate could spark next pandemic

      A VIRUS with a 75 percent mortality rate could cause the next pandemic, experts have warned.

      Sat, Feb 20, 2021

      Dr Rebecca Dutch, chair of the University of Kentucky's department of Molecular and Cellular Biochemistry, told the Sun: “Nipah is one of the viruses that could absolutely be the cause of a new pandemic.

      "Several things about Nipah are very concerning.

      “Many other viruses in that family transmit well between people, so there is concern that a Nipah variant with increased transmission could arise.

      “The mortality rate for this virus is between 45 percent and 75 percent depending on the outbreak – so this is much higher than COVID-19.
      "Nipah has been shown to transmit through food, as well as via contact with human or animal excretions.

      “The incubation period for Nipah can be quite long, and it can be unclear if transmission can occur during this time.”

      Dr Jonathan Epstein, vice president for science and outreach at the EcoHealth Alliance, added: “We know very little about the genetic variety of Nipah-related viruses in bats, and what we don’t want to happen is for a strain to emerge that is more transmissible among people.

      “So far, Nipah is spread among close contact with an infected person, particularly someone with respiratory illness through droplets,
      and we generally don’t see large chains of transmission...“This is a zoonotic virus knocking on the door, and we have to really work now to understand where human cases are occurring,..


      • #4
        Cross‐species transmission of the newly identified coronavirus 2019‐nCoV

        Wei Ji

        Wei Wang

        Xiaofang Zhao

        Junjie Zai

        Xingguang Li
        First published: 22 January 2020


        • #5
          Twin Ebola, COVID-19 threats a danger to West Africa

          February 18, 2021 22:09

          ...Now, with a new Ebola outbreak in the DRC and Guinea, there are fears of a compounding of problems for these countries and the region as a whole, with the coronavirus disease (COVID-19) already omnipresent.
          The mix of the two diseases illustrates how pathogens emerge simultaneously and why the global community is making disease monitoring and maintenance such a key priority. Just as with COVID-19, gene sequencing of Ebola samples from both the DRC and Guinea is being carried out to learn more about the origins of the outbreaks and to identify the strains.

          So far, the news is positive, in that this outbreak is not an Ebola mutation. The DRC has confirmed that its latest cases are not linked to a new Ebola variant. Instead, preliminary analysis shows the resurgence to be the 10th outbreak — .......
          ..Further spread of the disease could cripple the region’s under-funded health systems, which are also battling the coronavirus pandemic. The Ivory Coast, Mali and Sierra Leone launched plans to stop any spread by reinforcing border controls, on top of their COVID-19-related measures. Given the generally porous borders, however, the possibility of disease spread is high. There are no known combined Ebola-COVID-19 cases yet. What the mix means in terms of environment requirements examination.....


          • #6
            If someone has ebola and doesn't show symptoms for 2 or 3 weeks..and has covid and is coughing "saliva" onto public objects or other people, than why wouldn't it be passed to others? or both?




            • #7
              WHO: World needs to prepare for the next virus

              Experts warn of a newer and more deadly virus that has been identified in Southeast Asia
              Shlomo Witty , Feb 21 , 2021 9:45 PM
              The World Health Organization today (Sunday) took the first step in fighting a possible outbreak of the ‘Nipah’ virus, which causes an incurable disease that kills two-thirds of patients, and put the virus on a list of pathogens that endanger humanity.

              The inclusion of the deadly virus on the list will enable funding for research and search for drugs and treatments for the serious illness caused by exposure to the virus, which originated in fruit bats and last erupted in China. According to a report in the British "Sun", the biggest concern among experts is from a variant of Nipah disease that will turn out to be more contagious to humans.

              Israel Hayom quotes Dr. Jonathan Epstein, vice president of the EcoHealth Alliance, the world's largest non-governmental organization for infectious diseases, explained to Sun: "We know very little about the genetic diversity of ‘Nipah’ in bats, and what we fear is a strain that is more contagious to humans.”....



              • #8
                There's multiple risks here, some more concerning than others, and I fear we're conflating them:

                - The risk of a virus being produced with genetic material from both COVID and Ebola as a result of a co-infection is essentially zero. They're too dissimilar. It's worth pointing out that Ebola patients in the past have been co-infected with many other viruses, including HIV, flu, measles, etc. without producing a hybrid virus.

                - The risk of a respiratory infection with COVID in an Ebola resulting in the mechanical expulsion of bodily fluids containing both viruses. This could easily result in a superspreader event. It's worth pointing out, however, that both viruses are capable of producing superspreader events even without such co-infection. A really good example is the index case in Nigeria in the 2013-16 Ebola outbreak, that infected over a dozen other people as a result of his actions while severely ill.

                - The risk that Ebola itself could mutate into a more transmissible form and cause a much worse pandemic. Obviously, this is possible, but there's no way to estimate how likely it is.

                - The risk that some other virus will have the lethality of Ebola and the transmissibility of COVID and cause a catastrophic pandemic. This is a real risk. I think I agree with Treyfish that among known viruses, Nipah probably presents the greatest risk, but let us not forget the risk of something we never saw coming. And I would argue the same zoonotic reservoirs that brought us SARS and COVID could easily cook up a third surprise as well.

                - H5N1. It's still out there. Just because we haven't had an H5N1 pandemic yet doesn't mean we can't. And we'd have to be lucky as all hell for an H5N1 pandemic to be less severe than COVID, even with vaccines and antivirals.


                • Emily
                  Emily commented
                  Editing a comment
                  Agree H5N1 could be worse, at least in the sense that it could affect a younger, healthier population. The current coronavirus seems like an attenuated virus that would be used in vaccine challenge experiments against a much deadlier virus.

              • #9
                My questions on H5N8 is nobody in India or SK has caught it yet but Russia had 7 catch it on 1 farm and doesn’t tell anyone for 2 months. So did it go H2H or all the guys catch it from the same chicken? Or were there multiple chickens handing it out?



                • #10
                  Has testing of humans for asymptomatic and mild H5N8 bird flu begun in other nations with H5N8 outbreaks after seven infected workers in Russia’s Astrakhan region?

                  FEBRUARY 21, 2021.

                  By Daniel R. Lucey MD, MPH, FIDSA

                  On Saturday (Feb. 20 ), the Russian news agency TASS reported:

                  “At the beginning of December 2020, an outbreak of bird flu occurred at a poultry farm in Akhtubinsky district . . . During this period, seven employees of the poultry farm had a slight health disorder (sore throat) . . .”....

                  Specific studies to assess asymptomatic transmission of H5N8 from person-to-person must also be undertaken. This is especially true given the experience with COVID-19 pandemic, another “Disease X” novel virus for which asymptomatic and pre-symptomatic transmission was initially underappreciated......

                  An earlier TASS article, on Dec. 16, had reported:

                  “The poultry population at the Vladimirovskaya poultry farm in the Akhtubinsky district of the Astrakhan region, numbering more than 800 thousand heads, will be completely eliminated due to an outbreak of bird flu . . . An outbreak of bird flu at the enterprise was detected on December 8. The poultry farm was quarantined, and the city of Akhtubinsk and the nearest village were also supervised.”....

                  ...Importantly, there are very likely more human infections with H5N8 avian flu if the genetic sequence of the H5N8 virus causing the infections in these seven humans is the same as the H5N8 virus outbreaks in some of the 17 other European and 4 Middle East nations reported since October 2020 by the UN Food and Agriculture Organization (FAO) (see Table for nation-by-nation listing). ....



                  • #11
                    THE PHILIPPINES has temporarily banned poultry imports from the Russian Federation after that country reported the world’s first case of human transmission of H5N8 highly pathogenic avian influenza (bird flu)...



                    • #12
                      Inside Lagos’ wet markets: where dead and alive pangolins, sea turtles and monkeys being sold as experts fear next virus could come from Nigeria

                      News Wire
                      February 28, 2021

                      GRAPHIC WARNING: Animals including pangolins, primates and sea turtles are seen at a Nigerian wet market
                      Wild animals that are thought to have been illegally killed are found both dead and alive at Oluwu fish market

                      Exclusive footage shows vendors keeping animals in unhygienic conditions and not wearing any form of PPE

                      Experts warn environments like these are a perfect melting pot for zoonotic diseases, such as SARS-CoV-2
                      Shocking footage seen by MailOnline reveals the appalling state of Nigerian wet markets which have the potential
                      to cause future disease outbreaks in humans....



                      • #13

                        MARCH 1, 2021ยท
                        Amid mutton shortage, camel meat tickles taste buds in Kashmir

                        Srinagar: Forget mutton, camel meat is tickling taste buds in Kashmir.
                        Demand for camel meat has witnessed an increase amid the ongoing mutton shortage in the Kashmir valley. Several mutton retailers are presently selling camel meat even as the deadlock between the dealers and government has not ended to date.

                        “Mutton retailers had earlier started selling chicken due to mutton shortage. And now I bought camel meat from a retailer at Natipora. I also noticed another retailer selling the same at Mehjoor Nagar, Batamaloo, Parimpora and a few other places in the city. Several people are scared to buy chicken due to bird flu and camel meat has come across as a good alternative to mutton,” said Omar Bhat, a customer....



                        • #14
                          EU must prepare for ‘era of pandemics’, von der Leyen says

                          Europe must prepare its medical sector to cope with an “era of pandemics”, the European Commission president said, as she warned the bloc was still in its most difficult period for Covid-19 vaccine deliveries. Ursula von der Leyen told the Financial Times that the EU could not afford to sit still even once Covid-19 has been overcome, as she described her plans for a Europewide fast-reaction system designed to respond more quickly to emerging medical threats.

                          “Europe is determined to enlarge its strength in vaccine production,” she said in a telephone interview. “It’s an era of pandemics we are entering. If you look at what has been happening over the past few years, I mean from HIV to Ebola to MERS to SARS, these were all epidemics which could be contained, but we should not think it is all over when we’ve overcome Covid-19. The risk is still there.” Von der Leyen last month unveiled plans for a biodefence preparedness plan called the HERA Incubator, which will combine researchers, biotech companies, manufacturers and public authorities to monitor emerging threats and work on adapting vaccines....



                          • #15
                            .....Two viral-vector Ebola vaccines have been cleared for use.

                            However, there is but one inhibition about the use of viral-vector technology. Some fear that people could develop an immunity to the vaccine itself, potentially making it less effective against new variants of the coronavirus or another type of outbreak.

                            A viral-vector Covid-19 vaccine developed in China didn’t perform as well in some people during testing because subjects had pre-existing immunity to the underlying virus that was used.

                            WSJ’s report states that one way around the challenge is to use a virus from another species. The viral-vector vaccine from AstraZeneca PLC and its partner University of Oxford, which is being tested in the U.S., uses a chimpanzee adenovirus.