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Discussion thread VI - COVID-19 (new coronavirus)

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  • #61
    ColdZyme containes glycerol, water, cod trypsin, ethanol, calcium chloride, tris and menthol.

    The Journal of Medical Virology has peer reviewed, approved and published the results of Enzymatica’s in vitro study on SARS-CoV-2

    On July 20 Enzymatica announced the preliminary results from the in vitro study, showing that the mouth spray ColdZyme? deactivates SARS-CoV-2, the virus causing the COVID-19 pandemic. The results of the study, which also includes the common cold virus HCoV-229E, have now been published in the Journal of Medical Virology in the article “Inactivation of SARS-CoV-2 and HCoV-229E in vitro by a medical device mouth spray”.

    The conclusion of the study is that the mouth spray ColdZyme can inactivate the respiratory coronaviruses SARS‐CoV‐2 and HCoV‐229E in vitro, by 98.3% and 99.9% respectively. Although the in vitro results presented cannot be directly translated into clinical efficacy, the study indicates that ColdZyme might offer a protective barrier against SARS‐CoV‐2 and a decreased risk of COVID‐19 transmission.



    Comment


    • #62
      Mask litter is an overlooked risk for spreading coronavirus, Air Force official says

      By ERICA EARL | STARS AND STRIPES
      Published: October 8, 2020

      YOKOTA AIR BASE, Japan — They are everywhere in the coronavirus pandemic and easily spotted almost any place in Japan: face masks.

      They fall from pockets or are callously discarded; they lie limp in parking lots or collect in gutters.

      At Yokota, the home of U.S. Forces Japan in western Tokyo, littered and improperly discarded masks are an overlooked risk for spreading the coronavirus, said Senior Master Sgt. Charles Patterson, the superintendent for operations and engineering for the 374th Civil Engineering Squadron, on Tuesday.

      “Anyone on quarantine who has either tested positive or may potentially have coronavirus creates a contact hazard for anything they have touched,” he said.

      ... Yokota is one of only a few U.S. installations in the region to have an incinerator on base
      Not just masks, but all garbage generated by quarantined personnel is burned; none of it is recycled, Patterson said. Incinerating all that trash protects the base population from viruses present even on plastic, he said.

      Properly disposing of masks can help stem the coronavirus' spread, according to the superintendent for operations and engineering for the 374th Civil Engineering Squadron.

      Comment


      • #63
        Bill Gates says that monoclonal antibodies like Regeneron, (med that Trump credits being so helpful), are the most exciting interventions his foundation has been looking at. He also was hopeful they might be able to get the cost of treatment down to around $100, if they can use low doses. (Though that is the best case scenario.)
        Last edited by Emily; October 9, 2020, 03:38 AM. Reason: Added price info.
        _____________________________________________

        Ask Congress to Investigate COVID Origins and Government Response to Pandemic.

        i love myself. the quietest. simplest. most powerful. revolution ever. ---- nayyirah waheed

        "...there’s an obvious contest that’s happening between different sectors of the colonial ruling class in this country. And they would, if they could, lump us into their beef, their struggle." ---- Omali Yeshitela, African People’s Socialist Party

        (My posts are not intended as advice or professional assessments of any kind.)
        Never forget Excalibur.

        Comment


        • JJackson
          JJackson commented
          Editing a comment
          The problem with Mabs and anitvirals is the lack of rapid testing. For most people if you get tested shortly after getting symptoms and it takes a few days to get back your results then the viral phase is already waning. The President may get regular fast testing but not many others do.

        • Emily
          Emily commented
          Editing a comment
          I thought we were able to get faster turn-around on testing now, but I'm not up on the testing. About 3 min in is when Gates talks about all this. He said a positive test plus and oxygen dip plus age of 60+ was a good target for starting Regeneron. The Foundation has factories set to go already. If they think this might work in less privileged places, then we should be able to pull it off in the US.

      • #64
        Moved to another thread

        The Coronavirus Unveiled: Microscopic Images of SARS-CoV-2
        By Carl Zimmer (https://www.nytimes.com/by/carl-zimmer) Oct. 9, 2020 Dr. Li, a structural biologist at Tsinghua University in Beijing, joined forces with virologists who were rearing the virus in a biosafety lab in the city of Hangzhou. Those researchers doused the viruses with chemicals to render them harmless and then sent

        Comment


        • #65
          obviously COVID is seasonal. Why didn't we figure that out earlier.
          Maybe misguided by the USA-South-wave in hot summer. I assume, tht would have been much worse in winter.
          Flu and other respiratory viruses also sometimes hit in summer,
          remember the 2009-NYC-wave, 1918 in summer ; but usually it's worse in winter.
          In ancient times we had flu in summer more often, maybe because of reduced traveling in winter.

          Now, the deathrates are currently low, but they were much higher in March, may they rise again
          during winter with less vit.D, other viruses around ?


          I'm interested in expert panflu damage estimates
          my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

          Comment


          • #66

            China - COVID-19 - 1st known case traces back to November 2019 - FluTrackers documentation of possible early 2019 outbreak trend

            Comment


            • #67

              "UW Medicine is running a trial for those who have not already been infected, but who have been exposed, to find out if the drug can prevent people from getting coronavirus.

              Swedish is also testing the drug on patients who already have COVID-19 to see if the drug can slow symptoms."
              _____________________________________________

              Ask Congress to Investigate COVID Origins and Government Response to Pandemic.

              i love myself. the quietest. simplest. most powerful. revolution ever. ---- nayyirah waheed

              "...there’s an obvious contest that’s happening between different sectors of the colonial ruling class in this country. And they would, if they could, lump us into their beef, their struggle." ---- Omali Yeshitela, African People’s Socialist Party

              (My posts are not intended as advice or professional assessments of any kind.)
              Never forget Excalibur.

              Comment


            • #68

              WHO - David Nabarro: "We believe lock downs only serve one purpose, and that is to give you a bit of breathing space......" - October 8, 2020
              Last edited by sharon sanders; October 11, 2020, 07:06 PM. Reason: typo in name

              Comment


              • cartski
                cartski commented
                Editing a comment
                But does “lockdown” mean “stay inside” when there’s evidence that sunlight is effective at destroying the virus.

                Sunlight is effective in destroying the virus, both airborne and fomites:

                Ratnesar-Shumate S, Williams G, Green B, Krause M, Holland B, Wood S, et al. Simulated sunlight rapidly inactivates SARS-CoV-2 on surfaces. J Infect Dis. 2020;222(2):214–22.

                CAS Article Google Scholar
                31.

                Schuit M, Ratnesar-Shumate S, Yolitz J, Williams G, Weaver W, Green B, et al. Airborne SARS-CoV-2 is rapidly inactivated by simulated sunlight. J Infect Dis. 2020;222(4):564–71.

                CAS Article Google Scholar

              • flatlander
                flatlander commented
                Editing a comment
                I thought the lockdown/mask data was actually all over the place. It looked as though in someplace it may have worked but in others the virus still spread. I haven't dug completely into the WHOs reasonings but my understanding of the cliff notes version is that they are concerned about the harm lockdowns are doing to less advantaged people. I believe that indicates they must feel that the harm is out weighing the believed benefits of locking down whole societies. The increase in poverty, hunger, suicide all are going up in many places add to those the projected deaths in people who are not being treated for treatable illnesses right now and you can see the concern. In the end the cure can't be worse than the disease.

              • gsgs
                gsgs commented
                Editing a comment
                well, I've learned over the decades that much what the doctor's and pharmacists' groups say are mainly
                motivated by their own finances (which they won't say) and only secondary by public health issues
                (what they highlight).

                And with people avoiding doctor visits and hospitals during lockdown this could also be bad for doctor's finances

                It's not a useful discussion when one group just mentions the pros and another group the cons.
                You must weight them. Make lists, assign numbers to the points, discuss the single numbers.

            • #69


              SAGE advised a 2-week-lockdown in UK 3 weeks ago "circuit-breaker"
              also restrictions for household-mixing,bars,restaurants
              but Johnson ignored it

              newspaper story :
              https://www.businessinsider.com/bori...0-10?r=DE&IR=T

              SAGE-documents :
              https://assets.publishing.service.go...n_Covid-19.pdf

              on Sep.21 , when the UK had _5000 cases/day,40deaths/day they recommended :
              a) A circuit-breaker (short period of lockdown) to return incidence to low levels
              b) Advice to work from home for those for all those that can
              c) Banning all contact within the home with members of other households
              (except members of a support bubble)
              d) closure of all bars, restaurants, cafes, indoor gyms, and personal servies
              (e.g. hairdressers)
              e) all university and college teaching to be online unless face-to-face teaching
              is absolutely essential.

              SAGE , 58th meeting
              27 Scientific experts
              10 Observers
              14 secretariat


              https://en.wikipedia.org/wiki/Scient...or_Emergencies

              ================================================== =
              I'm interested in expert panflu damage estimates
              my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

              Comment


              • #70

                "It's not a useful discussion when one group just mentions the pros and another group the cons.
                You must weight them. Make lists, assign numbers to the points, discuss the single numbers."
                VERY WISE WORDS

                Comment


                • #71
                  Extra safety scrutiny planned as virus vaccine worries grow

                  By LAURAN NEERGAARD
                  today

                  Facing public skepticism about rushed COVID-19 vaccines, U.S. health officials are planning extra scrutiny of the first people vaccinated when shots become available — an added safety layer experts call vital.
                  A new poll suggests those vaccine fears are growing. With this week’s pause of a second major vaccine study because of an unexplained illness ...

                  ... On top of rigorous final testing in tens of thousands of people, any COVID-19 vaccines cleared for widespread use will get additional safety evaluation as they’re rolled out. Among plans from the Centers for Disease Control and Prevention: Texting early vaccine recipients to check how they’re feeling, daily for the first week and then weekly out to six weeks.

                  Dr. Anthony Fauci, the top U.S. infectious diseases expert, says that should be reassuring because it means scientists like himself will see all the evidence.

                  Facing public skepticism about rushed COVID-19 vaccines, U.S. health officials are planning extra scrutiny of the first people vaccinated when shots become available — an added safety layer experts call vital.

                  Comment


                  • #72
                    W.H.O. Europe chief: "this is the time to step up the restrictive measures ... with lockdowns as a very, very last resort." - October 15, 2020

                    Comment


                    • gsgs
                      gsgs commented
                      Editing a comment
                      why did you lockdown ?
                      Madrid : WHO recommended it.

                  • #73
                    How Does a Pandemic End? Here's What We Can Learn From the 1918 Flu

                    BY OLIVIA B. WAXMAN
                    UPDATED: OCTOBER 7, 2020 4:52 PM EDT | ORIGINALLY PUBLISHED: OCTOBER 6, 2020 5:07 PM EDT

                    More than six months after the World Health Organization declared COVID-19 a pandemic, as scientific understanding of the novel coronavirus continues to evolve, one question remains decidedly unanswered. How will this pandemic come to an end?

                    Current scientific understanding is that only a vaccine will put an end to this pandemic, but how we get there remains to be seen. It seems safe to say, however, that some day, somehow, it will end. After all, other viral pandemics have. Take, for example, the flu pandemic of 1918-1919.

                    That pandemic was the deadliest in the 20th century; it infected about 500 million people and killed at least 50 million, including 675,000 in the United States.



                    Comment


                    • Mary Wilson
                      Mary Wilson commented
                      Editing a comment
                      Just a side-note: A story from my Mom, at the start of this pandemic.
                      Her father's brother was stationed on the East coast at a US military base.
                      My grandpa was notified that his brother had come done with the (1918) flu.
                      He immediately left home to see his sick brother. When he arrived his brother had died.
                      Family stories are meant to be treasured, listen to your elders.

                    • JJackson
                      JJackson commented
                      Editing a comment
                      Not convinced by her argument. The 1918 pandemic did end when it was displaced in 1957. It did make a comeback about twenty years later but was again displaced in 2009 by our current flavour of H1N1. HIV is a classic pandemic and is doing fine. The colds we get in winter came from animals and have not ended they are just endemic diseases. I see no reason why this corona virus should not follow the same path. Unless the vaccines produced a much more potent immune response than a natural infection then we should expect to be susceptible to reinfection within a couple of years. Even if it was 100% effective at stopping infection and shedding we would need to produce and distribute about 3 billion doses annually to maintain herd immunity. I see no likely route to eradication we are going to have to live with this for a while and hope the vaccines can give a good level of protection for some years against severe disease and a new host/pathogen equilibrium can be reached that is less painful to the host.

                    • sharon sanders
                      sharon sanders commented
                      Editing a comment
                      Coronavirus is a different virus than influenza virus.

                  • #74
                    I just wanted to say that I am not spending much time on the US because it is so widely published that we are screwed. I try to spend my time on lessor known situations, like China developments. The combination of the US media and the various tracking sites do a good job of letting everyone know where the hot spots are and what the general situation is. Please refer to your local news frequently to see what is happening in your local area.

                    If you are in the US just assume you are living in an environment where COVID-19 is prevalent. Act accordingly. As this site said in the spring - you are responsible for protecting yourself. Do not wait for the government. I related several times on previous threads my experiences with hurricane relief (not). I also said not to wait for vaccines.

                    So, bottom line, no matter what the government does, it is spread so thin that you personally will barely feel any results of their efforts. Establish your own "flu friend" network and support group.

                    Take care everyone.

                    Comment

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