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Discussion: Chinese Academy of Sciences (CAS) in Wuhan has been working with bats and coronavirus for many years - DNA manipulations, cloning....

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  • JJackson
    replied
    Virus Researchers Cast Doubt On Theory Of Coronavirus Lab Accident
    https://www.google.com/url?sa=t&rct=...Qv8mrfHarsyXkI

    By Geoff Brumfiel and Emily Kwong

    NPR.org, April 23, 2020 ? Virus researchers say there is virtually no chance that the new coronavirus was released as result of a laboratory accident in China or anywhere else.

    The assessment, made by more than half-a-dozen scientists familiar with lab accidents and how research on coronaviruses is conducted, casts doubt on recent claims that a mistake may have unleashed the coronavirus on the world.

    Leave a comment:


  • JJackson
    replied
    Claim That Coronavirus Came from a Lab in China Completely Unfounded, Scientists Say
    https://www.newsweek.com/claim-that-...ts-say-1498308

    There is no evidence to back claims the coronavirus that has caused the COVID-19 pandemic emerged from a lab in China, scientists have told Newsweek.

    Adam Lauring, an associate professor at the University of Michigan Medical School and an expert in the evolution of viruses, told Newsweek: "This claim is a conspiracy theory and it is not supported at all by the available data."

    Alexandre Hassanin, a lecturer at France's Sorbonne University National Museum of Natural History department of origins and evolution, similarly highlighted to Newsweek: "Even if it is difficult to prove that a laboratory accident did not take place, you should know that SARS-CoV-2 is not closely related to any previous viruses; it was never sequenced (even partially) in previous studies, and the COVID-19 outbreak began in November/December, as in previous SARS epidemic events (2002 and 2003)."

    Hassanin said: "These two points suggest therefore that the current outbreak was not the consequence of a laboratory accident."


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  • JJackson
    replied
    Did COVID-19 escape from a lab?
    https://allianceforscience.cornell.e...pe-from-a-lab/

    A frenzy of speculation has arisen around the idea that the novel coronavirus responsible for the global COVID-19 pandemic might originally have escaped from a laboratory in the Chinese city of Wuhan.

    While there is so far no evidence being offered to support this suggestion, the fact that the mere possibility is being reported in mainstream media outlets like the Washington Post and Yahoo News might seem to give credence to earlier conspiracy theories about the virus being engineered in a biowarfare laboratory and deliberately released into the human population.

    But don’t be fooled. Whether the virus first infected humans at the infamous Wuhan “wet market” or somehow took a more complicated route via a so far unidentified Chinese laboratory, the ultimate source of the novel coronavirus is still the same: wild populations of bats.
    The bat connection


    None of the current speculation changes the one fact that is established beyond reasonable doubt — SARS-CoV-2 is a zoonotic virus, meaning it came from an animal and jumped into the human population.

    It appears that the Wuhan Institute of Virology is currently under suspicion because its scientists were studying bat coronaviruses in order to evaluate the possibility of the emergence of just such a pandemic as is currently underway.

    Indeed, it is thanks to their work that we know that SARS-CoV-2 is 96 percent “identical at the whole-genome level to a bat coronavirus” (to quote from a Feb. 3 Nature paper co-authored by the institute’s scientists) and that its most likely original host is the horseshoe bat.


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  • JJackson
    replied
    Coronavirus: False claims by politicians debunked


    Stolen face masks, an effective cure and biological weaponry: Reality Check’s Chris Morris takes a look at some of the false coronavirus claims made by leading politicians.

    https://www.bbc.co.uk/news/av/522996...cians-debunked

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  • JJackson
    replied
    Coronavirus: US and China trade conspiracy theories

    https://www.bbc.co.uk/news/world-52224331

    From the early stages of the coronavirus outbreak, conspiracy theories about the origin and scale of the disease were spread on online platforms.

    Among these were the false claim that the virus was part of a Chinese "covert biological weapons programme", and a baseless claim that a Canadian-Chinese spy team had sent coronavirus to Wuhan.

    The claim that the virus was man-made has been pushed by numerous conspiracy groups on Facebook, obscure Twitter accounts and even found its way on to primetime Russian state TV.

    And months into the outbreak, not only have these theories not faded away, but new, unverified claims have been promoted by government officials, senior politicians and media outlets in China and the US.

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  • bertrand789
    replied
    Merci, c'est un honneur d'?tre un lecteur de ce lieu. Je retiens de ce texte, que le probl?me n'est pas chinois, mais mondial. Si la crise coronavirus pose des probl?mes, il peut y en avoir bien d'autres. Mon p?re a fait une m?ningite herp?tique suite ? un mauvais usage, notamment de cortico?des. Les herpes me semble de bons candidats pour faire bien des b?tises.
    Que les Chinois actent que la d?marche ONE HEALTH prenne une vraie place est le pr?alable. Je suis totalement contre la suppression de certaines pratiques culturelles alimentaires, si les ?tats ou cela se pratique font ce qui se doit. Mais, l'ensemble des scientifiques, qui travaillent sur les dangers microbiologiques, seraient bien inspir?s de faire leur part du travail... Je doute que l'O.M.S, vu son organisation actuelle, soit le bon lieu pour cela, mais je suis int?ress? de lire toutes les propositions positives pour faire ?merger ce qu'il faut pour maintenir les activit?s scientifiques et respecter la Vie... A ce stade ces solutions ne peuvent qu'?tre mondiale, c'est un sacr? d?fi...

    Leave a comment:


  • Kathy
    replied
    A very informative site on the topic possible genetic manipolation of SARS-CoV-2:

    https://medium.com/@yurideigin/lab-m...h-f96dd7413748

    Leave a comment:


  • bertrand789
    replied
    Je ne n'ai jamais fait la moindre critique des scientifiques chinois, je ne dispose pas des faits. Mais je connais les possibles et sans vraie r?ponse ? une question pos?e avec courtoisie, je reste dans le doute...

    C'est quand m?me plus simple pour permettre le passage, avec des animaux fait pour cela, que des sauvages. Mais ensuite cela va en bien des lieux, l'exemple du jour :

    Coronavirus : des visons d’?levage infect?s aux Pays-Bas, premier cas av?r? au monde

    https://www.sudouest.fr/2020/04/26/c...0976-10997.php

    Leave a comment:


  • sharon sanders
    commented on 's reply
    We should keep open minds on all issues about SARS-CoV-2. Science will lead us to the truth.

  • sharon sanders
    replied
    I disagree with JJackson's comment above. I think it is possible that what we know as COVID-19 is the result of the manipulation of genetic material. I personally do not know but I am keeping an open mind. Time will tell. We should let the science develop. Read through this thread to see some of the published work from both the Wuhan BL 4 lab and the China CDC lab in Wuhan.

    One thing is for sure - through science we will know the origins of this pandemic disease. We owe the thousands who have died to find out.

    FluTrackers is committed to a search for the truth - wherever it leads.

    Leave a comment:


  • bertrand789
    replied
    j'ai une question :
    pour r?cup?rer des virus dans un lieu, il faut faire des pr?l?vements ou laisser se promener des lign?es animales con?ues pour cela, du type de celles d?crites dans ces articles:
    https://www.ncbi.nlm.nih.gov/pubmed/17222058

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787736/

    La sous question devient : quid de la r?glementation quant ? la d?tention et des usages de ce type de lign?e ?
    En management, on utilise parfois des animaux sentinelles, par exemple pour les influenza,on met des poules avec des canards. Les meilleurs animaux sentinelles, pour les coronavirus, ce ne sont pas alors ceux con?us en laboratoire, pour cela et mis ou il faut ?
    Je dis aussi cela car visiblement pour aller chercher des virus dans une grotte, vu les publications, cela a ?t? peut efficient et tr?s long. Faitre vivre des animaux sentinelles dans ces lieux, ce n'est pas plus simple ?

    Leave a comment:


  • JJackson
    commented on 's reply
    It is not a theory that must be censored, it is however a conspiracy theory that must be debunked and squashed as without scientific merit of any kind.

  • Kathy
    replied
    Is considering a genetic-manipulation origin for SARS-CoV-2 a conspiracy theory that must be censored?

    Rossana Segreto1#(Ph.D.)

    Abstract

    The origin of SARS-CoV-2 is still controversial. Comparative genomic analyses have shown that SARS-CoV-2 is likely to be chimeric, most of its sequence being very close to the CoV detected from a bat, whereas its receptor binding domain is almost identical to that of CoV obtained from pangolins. The furin cleavage site in the spike protein of SARS-CoV-2 was previously not identified in other SARS-like CoVs and might have conferred ability to cross species and tissue barriers. Chimeric viruses can be the product of natural recombination or genetic manipulations. The latter could have aimed to identify pangolins as possible intermediate hosts for bat-CoV potentially pathogenic for humans. Theories that consider a possible artificial origin for SARS-CoV-2 are censored as they seem to support conspiracy theories. Researchers have the responsibility to carry out a thorough analysis, beyond any personal research interests, of all possible causes for SARS-CoV-2 emergence for preventing this from happening in the future.


    (PDF) Is considering a genetic-manipulation origin for SARS-CoV-2 a conspiracy theory that must be censored?. Available from: https://www.researchgate.net/publica...st_be_censored [accessed Apr 26 2020].

    Leave a comment:


  • Emily
    replied
    Originally posted by Pathfinder View Post
    Translation Google

    EXCLUSIVE - The thesis of a manipulated virus escaped from a Chinese laboratory: the pavement in the pool of Pr Luc Montagnier

    By Th. B.
    ...
    Posted on 04/16/2020 at 6:00 p.m. | |

    THE ESSENTIAL

    Professor Luc Montagnier, 2008 Nobel Prize laureate, says that SARS-CoV-2 is a manipulated virus accidentally released from a laboratory in Wuhan, China
    Chinese researchers reportedly used this coronavirus as part of work to develop an AIDS vaccine
    HIV DNA fragments allegedly found in the SARS-CoV-2 genome

    We knew the Chinese version of the emergence of the coronavirus more and more undermined, but here is a thesis that tells a whole different story about the Covid-19 pandemic already responsible for more than 120,000 deaths in the world. According to Professor Luc Montagnier, 2008 Nobel Prize in Medicine for having "co-discovered" the HIV causing the AIDS epidemic with Fran?ois Barr?-Sinoussi today affirmed that SARS-CoV-2 is a manipulated virus and accidentally left a laboratory in Wuhan, China during the last quarter of 2019. This laboratory known to work on coronaviruses, according to Professor Montagnier, sought to use one of these viruses as an HIV vector as part of the looking for an AIDS vaccine!

    "With my colleague, the bio-mathematician Jean-Claude Perez, we looked closely at the description of the genome of this RNA virus," explained Luc Montagnier, interviewed by Dr. Jean-Fran?ois Lemoine for the daily audio journal of Pourquoi Doctor , adding that others had already explored this track: "Indian researchers had already tried to publish the results of analyzes showing that this genome harbored sequences of another virus which is ... HIV, the virus of AIDS, but they were forced to retract, the pressures were too strong! ".

    "To insert an HIV sequence into this genome, you need molecular tools"
    [snip]
    https://www.ncbi.nlm.nih.gov/pubmed/17162377
    Clin Dev Immunol. 2006 Jun-Dec;13(2-4):353-60.
    Towards a coronavirus-based HIV multigene vaccine.
    Eriksson KK1, Makia D, Maier R, Ludewig B, Thiel V.
    Author information

    Abstract

    Human immunodeficiency virus (HIV) infection represents one of the major health threats in the developing world. The costly treatment of infected individuals with multiple highly efficient anti-HIV drugs is only affordable in industrialized countries. Thus, an efficient vaccination strategy is required to prevent the further spread of the infection. The molecular biology of coronaviruses and particular features of the human coronavirus 229E (HCoV 229E) indicate that HCoV 229E-based vaccine vectors can become a new class of highly efficient vaccines. First, the receptor of HCoV 229E, human aminopeptidase N (hAPN or CD13) is expressed mainly on human dendritic cells (DCs) and macrophages indicating that targeting of HCoV 229E-based vectors to professional antigen presenting cells can be achieved by receptor-mediated transduction. Second, HCoV 229E structural genes can be replaced by multiple transcriptional units encoding various antigens. These virus-like particles (VLPs) containing HCoV 229E-based vector RNA have the ability to transduce human DCs and to mediate heterologous gene expression in these cells. Finally, coronavirus infections are associated with mainly respiratory and enteric diseases, and natural transmission of coronaviruses occurs via mucosal surfaces. In humans, HCoV 229E causes common cold by infecting the upper respiratory tract. HCoV 229E infections are mainly encountered in children and re-infection occurs frequently in adults. It is thus most likely that pre-existing immunity against HCoV 229E will not significantly impact on the vaccination efficiency if HCoV 229E-based vectors are used in humans.
    HIV gp120 and gag discussed above and in retracted study.

    https://www.biorxiv.org/content/10.1...01.30.927871v1
    "Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV-1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature."

    It would be a total screw-up to mix up a common cold virus and a novel bat virus.

    Leave a comment:


  • sharon sanders
    replied
    posted with permission

    hat tip Jason Gale


    Chinese Ambassador to U.S. Urges ‘Serious Rethinking’ of Ties
    2020-04-22 06:09:29.947 GMT


    By Bloomberg News
    (Bloomberg) -- The Chinese ambassador to the U.S. called
    for a “serious rethinking” of relations between the world’s
    biggest economies in the face of the global coronavirus
    pandemic.
    “I think I should be hoping for more than just a pause in
    tensions, but really a serious rethinking of the very
    foundations of this important relationship,” Cui Tiankai said in
    response to a question on U.S.-China ties during a Bloomberg New
    Economy webcast on Tuesday.
    Relations between the countries have continued to
    deteriorate even after President Donald Trump and his Chinese
    counterpart Xi Jinping agreed last month in a phone call to dial
    down hostilities.
    The U.S. leader, who is facing re-election this year, again
    fanned speculation about the origins of the virus last weekend
    when he said China should face consequences if it was “knowingly
    responsible” for the outbreak. Missouri this week sued the
    Chinese government for what it alleged was covering up the
    extent of the coronavirus epidemic. China has denied those
    claims, saying it has been transparent about the virus all
    along.

    Cui defended China’s record on transparency, saying the
    country has shared all information it has with the World Health
    Organization. He went on to criticize some U.S. politicians for
    not paying enough attention to views from scientists, instead
    being “preoccupied in their efforts for stigmatization and
    groundless accusation.” He added that he’s concerned with the
    “anything but China” mindset, in response to criticism that
    Beijing has used medical donations for geopolitical purposes.

    ‘Shared Vulnerability’

    Cui also rejected the idea that U.S.-China ties should be
    defined as a strategic rivalry, particularly as the countries
    are now faced with “shared vulnerability” amid the virus.
    “Hopefully this pandemic will teach all of us a good lesson,” he
    said, adding that the relationship should “be based on a more
    realistic, forward-looking foundation.”
    Cui said that China has done its best to achieve trust with
    the U.S., and stands for dialogue as more discussion is needed.
    “Fortunately at the top level, there has been a good working
    relationship between the two presidents,” Cui said. “But of
    course we have to do more at lower levels.”
    Cui has emerged as a voice of caution on U.S.-China
    relations. In March, he distanced himself from tweets by foreign
    ministry spokesman Zhao Lijian, who speculated that the U.S.
    Army may have brought the virus to Wuhan. Cui described such
    speculation as “very harmful” and said investigations of the
    virus’s origin were best left to scientists. Zhao has since
    stopped promoting such claims.

    Rare Spat Between Chinese Diplomats Signals Split Over
    Trump
    Cui added that China’s development has not come at the
    expense of the U.S., saying China wants “nothing to do with U.S.
    domestic politics, we can’t even make sense of it,” in response
    to a question on who China would prefer to win the presidential
    election in November.
    “American people are most concerned about their own daily
    lives, and don’t want to make China the centerpiece of their
    domestic political debate,” he said.

    To contact Bloomberg News staff for this story:
    Sharon Chen in Beijing at schen462@bloomberg.net;
    Jing Li in Beijing at jli1638@bloomberg.net;
    Peter Martin in Beijing at pmartin138@bloomberg.net
    To contact the editors responsible for this story:
    Brendan Scott at bscott66@bloomberg.net
    Jodi Schneider, Daniel Ten Kate

    Leave a comment:

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