Tweet
Euro Surveill. Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada?s sentinel surveillance network, January 2014
[Source: Eurosurveillance, full page: (LINK). Abstract, edited.]
Eurosurveillance, Volume 19, Issue 5, 06 February 2014
Rapid communications
Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada?s sentinel surveillance network, January 2014
D M Skowronski <SUP>1</SUP><SUP>,2</SUP>, C Chambers<SUP>1</SUP>, S Sabaiduc<SUP>1</SUP>, G De Serres<SUP>3</SUP><SUP>,4</SUP><SUP>,5</SUP>, J A Dickinson<SUP>6</SUP>, A L Winter<SUP>7</SUP>, K Fonseca<SUP>6</SUP><SUP>,8</SUP>, J B Gubbay<SUP>7</SUP><SUP>,9</SUP>, H Charest<SUP>3</SUP>, M Petric<SUP>1</SUP><SUP>,2</SUP>, M Krajden<SUP>1</SUP><SUP>,2</SUP>, S M Mahmud<SUP>10</SUP><SUP>,11</SUP>, P Van Caeseele<SUP>11</SUP><SUP>,12</SUP>, T L Kwindt<SUP>1</SUP><SUP>,2</SUP>, A Eshaghi<SUP>7</SUP>, N Bastien<SUP>13</SUP>, Y Li<SUP>11</SUP><SUP>,13</SUP>
<SUP></SUP>
<SUP>1</SUP>British Columbia Centre for Disease Control, Vancouver, Canada - 2 University of British Columbia, Vancouver, Canada - 3 Institut National de Sant? Publique du Qu?bec (National Institute of Health of Quebec), Qu?bec, Canada - 4 Laval University, Quebec, Canada - 5 Centre Hospitalier Universitaire de Qu?bec (University Hospital Centre of Quebec), Qu?bec, Canada - 6 University of Calgary, Calgary, Canada - 7 Public Health Ontario, Toronto, Canada - 8 Alberta Provincial Laboratory, Calgary, Canada - 9 University of Toronto, Toronto, Canada - 10 Winnipeg Regional Health Authority, Winnipeg, Canada - 11 University of Manitoba, Winnipeg, Canada - 12 Cadham Provincial Laboratory, Winnipeg, Canada - 13 National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada
_____
Citation style for this article: Skowronski DM, Chambers C, Sabaiduc S, De Serres G, Dickinson JA, Winter AL, Fonseca K, Gubbay JB, Charest H, Petric M, Krajden M, Mahmud SM, Van Caeseele P, Kwindt TL, Eshaghi A, Bastien N, Li Y. Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada?s sentinel surveillance network, January 2014. Euro Surveill. 2014;19(5):pii=20690. Available online: http://www.eurosurveillance.org/View...rticleId=20690
Date of submission: 29 January 2014
_________
The 2013/14 influenza season to date in Canada has been characterised by predominant (90%) A(H1N1)pdm09 activity. Vaccine effectiveness (VE) was assessed in January 2014 by Canada?s sentinel surveillance network using a test-negative case?control design. Interim adjusted-VE against medically-attended laboratory-confirmed influenza A(H1N1)pdm09 infection was 74% (95% CI: 58?83). Relative to vaccine, A(H1N1)pdm09 viruses were antigenically similar and genetically well conserved, with most showing just three mutations across the 50 amino acids comprising antigenic sites of the haemagglutinin protein.
-
-------
Eurosurveillance, Volume 19, Issue 5, 06 February 2014
Rapid communications
Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada?s sentinel surveillance network, January 2014
D M Skowronski <SUP>1</SUP><SUP>,2</SUP>, C Chambers<SUP>1</SUP>, S Sabaiduc<SUP>1</SUP>, G De Serres<SUP>3</SUP><SUP>,4</SUP><SUP>,5</SUP>, J A Dickinson<SUP>6</SUP>, A L Winter<SUP>7</SUP>, K Fonseca<SUP>6</SUP><SUP>,8</SUP>, J B Gubbay<SUP>7</SUP><SUP>,9</SUP>, H Charest<SUP>3</SUP>, M Petric<SUP>1</SUP><SUP>,2</SUP>, M Krajden<SUP>1</SUP><SUP>,2</SUP>, S M Mahmud<SUP>10</SUP><SUP>,11</SUP>, P Van Caeseele<SUP>11</SUP><SUP>,12</SUP>, T L Kwindt<SUP>1</SUP><SUP>,2</SUP>, A Eshaghi<SUP>7</SUP>, N Bastien<SUP>13</SUP>, Y Li<SUP>11</SUP><SUP>,13</SUP>
<SUP></SUP>
<SUP>1</SUP>British Columbia Centre for Disease Control, Vancouver, Canada - 2 University of British Columbia, Vancouver, Canada - 3 Institut National de Sant? Publique du Qu?bec (National Institute of Health of Quebec), Qu?bec, Canada - 4 Laval University, Quebec, Canada - 5 Centre Hospitalier Universitaire de Qu?bec (University Hospital Centre of Quebec), Qu?bec, Canada - 6 University of Calgary, Calgary, Canada - 7 Public Health Ontario, Toronto, Canada - 8 Alberta Provincial Laboratory, Calgary, Canada - 9 University of Toronto, Toronto, Canada - 10 Winnipeg Regional Health Authority, Winnipeg, Canada - 11 University of Manitoba, Winnipeg, Canada - 12 Cadham Provincial Laboratory, Winnipeg, Canada - 13 National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada
_____
Citation style for this article: Skowronski DM, Chambers C, Sabaiduc S, De Serres G, Dickinson JA, Winter AL, Fonseca K, Gubbay JB, Charest H, Petric M, Krajden M, Mahmud SM, Van Caeseele P, Kwindt TL, Eshaghi A, Bastien N, Li Y. Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada?s sentinel surveillance network, January 2014. Euro Surveill. 2014;19(5):pii=20690. Available online: http://www.eurosurveillance.org/View...rticleId=20690
Date of submission: 29 January 2014
_________
The 2013/14 influenza season to date in Canada has been characterised by predominant (90%) A(H1N1)pdm09 activity. Vaccine effectiveness (VE) was assessed in January 2014 by Canada?s sentinel surveillance network using a test-negative case?control design. Interim adjusted-VE against medically-attended laboratory-confirmed influenza A(H1N1)pdm09 infection was 74% (95% CI: 58?83). Relative to vaccine, A(H1N1)pdm09 viruses were antigenically similar and genetically well conserved, with most showing just three mutations across the 50 amino acids comprising antigenic sites of the haemagglutinin protein.
-
-------
Comment