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Study: Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua

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  • Study: Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua

    Source: https://journals.plos.org/plosmedici...l.pmed.1002726

    Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua

    Aubree Gordon, Lionel Gresh , Sergio Ojeda, Leah C. Katzelnick, Nery Sanchez, Juan Carlos Mercado, Gerardo Chowell, Brenda Lopez, Douglas Elizondo, Josefina Coloma,
    Raquel Burger-Calderon, Guillermina Kuan, Angel Balmaseda,
    Eva Harris

    PLOS
    Published: January 22, 2019
    https://doi.org/10.1371/journal.pmed.1002726

    Abstract
    Background

    Zika virus (ZIKV) emerged in northeast Brazil in 2015 and spread rapidly across the Americas, in populations that have been largely exposed to dengue virus (DENV). The impact of prior DENV infection on ZIKV infection outcome remains unclear. To study this potential impact, we analyzed the large 2016 Zika epidemic in Managua, Nicaragua, in a pediatric cohort with well-characterized DENV infection histories...


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