Source: https://journals.plos.org/plosmedici...l.pmed.1002726
Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua
Aubree Gordon, Lionel Gresh , Sergio Ojeda, Leah C. Katzelnick, Nery Sanchez, Juan Carlos Mercado, Gerardo Chowell, Brenda Lopez, Douglas Elizondo, Josefina Coloma,
Raquel Burger-Calderon, Guillermina Kuan, Angel Balmaseda,
Eva Harris
PLOS
Published: January 22, 2019
Abstract
Background
Zika virus (ZIKV) emerged in northeast Brazil in 2015 and spread rapidly across the Americas, in populations that have been largely exposed to dengue virus (DENV). The impact of prior DENV infection on ZIKV infection outcome remains unclear. To study this potential impact, we analyzed the large 2016 Zika epidemic in Managua, Nicaragua, in a pediatric cohort with well-characterized DENV infection histories...
Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua
Aubree Gordon, Lionel Gresh , Sergio Ojeda, Leah C. Katzelnick, Nery Sanchez, Juan Carlos Mercado, Gerardo Chowell, Brenda Lopez, Douglas Elizondo, Josefina Coloma,
Raquel Burger-Calderon, Guillermina Kuan, Angel Balmaseda,
Eva Harris
PLOS
Published: January 22, 2019
Abstract
Background
Zika virus (ZIKV) emerged in northeast Brazil in 2015 and spread rapidly across the Americas, in populations that have been largely exposed to dengue virus (DENV). The impact of prior DENV infection on ZIKV infection outcome remains unclear. To study this potential impact, we analyzed the large 2016 Zika epidemic in Managua, Nicaragua, in a pediatric cohort with well-characterized DENV infection histories...