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Risk Factors for Middle East Respiratory Syndrome Coronavirus Infection among Healthcare Personnel

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  • Risk Factors for Middle East Respiratory Syndrome Coronavirus Infection among Healthcare Personnel

    Source: http://wwwnc.cdc.gov/eid/article/22/11/16-0920_article

    Volume 22, Number 11óNovember 2016

    Research

    Risk Factors for Middle East Respiratory Syndrome Coronavirus Infection among Healthcare Personnel

    Basem M. Alraddadi, Hanadi S. Al-Salmi, Kara Jacobs-Slifka, Rachel B. Slayton, Concepcion F. Estivariz, Andrew I. Geller, Hanan H. Al-Turkistani, Sanaa S. Al-Rehily, Haleema A. Alserehi, Ghassan Y. Wali, Abeer N. Alshukairi, Esam I. Azhar, Lia Haynes, David L. Swerdlow, John A. Jernigan1, and Tariq A. Madani1
    Author affiliations: King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia (B.M. Alraddadi, H.S. Al-Salmi, H.H. Al-Turkistani, S.S. Al-Rehily, H.A. Alserehi, G.Y. Wali, A.N. Alshukairi); Ministry of Health, Jeddah (B.M. Alraddadi, E.I. Azhar, T.A. Madani); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (K. Jacobs-Slifka, R.B. Slayton, C.F. Estivariz, A.I. Geller, L. Haynes, D.L. Swerdlow, J.A. Jernigan); King Abdulaziz University, Jeddah (E.I. Azhar, T.A. Madani)
    Suggested citation for this article
    Abstract

    Healthcare settings can amplify transmission of Middle East respiratory syndrome coronavirus (MERS-CoV), but knowledge gaps about the epidemiology of transmission remain. We conducted a retrospective cohort study among healthcare personnel in hospital units that treated MERS-CoV patients. Participants were interviewed about exposures to MERS-CoV patients, use of personal protective equipment, and signs and symptoms of illness after exposure. Infection status was determined by the presence of antibodies against MERS-CoV. To assess risk factors, we compared infected and uninfected participants. Healthcare personnel caring for MERS-CoV patients were at high risk for infection, but infection most often resulted in a relatively mild illness that might be unrecognized. In the healthcare personnel cohort reported here, infections occurred exclusively among those who had close contact with MERS-CoV patients...

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