Germany reports 3rd imported MERS-CoV case - confirmed death June 2015

[Gert van der Hoek]

computertranslation

Information by the RKI regarding a disease case by the MERS coronavirus

Status: 03/07/2015

Situation in Germany

In Germany, for the third time occurred a MERS-CoV case, as in the two previous cases, the disease was brought by a patient who arrived from the Arabian Peninsula. It is a 65-year-old German who had traveled to the United Arab Emirates, and is currently being treated at a hospital in Lower Saxony. In the Lower Saxony Minsterium of Health has informed in a press release on 7 March 2015 (see link below, all links mentioned here can be found at the end of the text).

People with close contact with the patient were determined and monitored by the relevant health authorities, the authorities are at the local and state level in close contact with the Robert Koch Institute. Generally MERS-CoV is not easily transferable, so that even in the case of secondary cases can not be expected that longer chains of infection occur. In Germany, therefore, there is no increased risk of disease in the general population.

[sharon sanders]

The other 2 cases are:


#6 - Man, 45, onset date October 12, 2012, traveled to Germany for treatment - recovered - Qatar

#17 - Man, 73, hospitalized in Germany reported by infectious diseases chief Wendtner at Schwabing Hospital in Munich - UAE Death

[tetano]

100 people are tested for deadly MERS virus

100 people from the family and clinic environment of the patient on the deadly coronavirus MERs are tested according to the German third case of the disease. The 65-year-old had become infected during a holiday trip in the United Arab Emirates with the pathogen. His condition is critical. He is treated to an isolation ward of the Osnabr?ck Marie hospital.



http://www.t-online.de/nachrichten/p...-getestet.html

[sharon sanders]

Reportedly he died:

The 65-year-old man, who died of MERS-related complications in a hospital in Lower Saxony on June 6, was infected during a trip to Abu Dhabi in February.

http://rt.com/news/267487-mers-europe-germany-death/

[Ronan Kelly]

Germany has reported its first death from the MERS virus
Reuters
CAROLINE COPLEY, REUTERS
JUN. 16, 2015, 8:34 AM 197


BERLIN (Reuters) - A 65-year-old German man who was infected with the Middle East Respiratory Syndrome (MERS) virus earlier this year has died in hospital, the health ministry of the German state of Lower Saxony said on Tuesday.

The man died in the town of Ostercappeln, north-west Germany on June 6 from complications stemming from the virus, the ministry said in a statement.

...


Read more: http://www.businessinsider.com/r-ger...#ixzz3dGlveqkn
Information of the RKI to disease cases by theMERS -Coronavirus

Stand: 16.06.2015
MERS in the Arabian Peninsula and in other countries (change)
The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) has been known since April 2012. Clinically proven cases presenting at the beginning with an acute beginning, influenza-like illness. The incubation period is usually one to two weeks. In severe cases, a pneumonia may develop, which may turn into an acute respiratory distress syndrome. A frequent concomitant symptom is diarrhea; in severe cases even kidney failure may occur. Severe cases occur predominantly in persons with chronic medical conditions, such as , for example,diabetes, cancer or immune suppression.
Since the first appearance of MERS 2012 were WHO reported over a thousand laboratory confirmed cases, especially in the Arabian Peninsula, about 40% of them died. The current state of play for diseases at the World Health Organization (WHO) available (see link below, all links mentioned here can be found at the end of the text).
All previous cases were associated directly or via another patient with the Arabian Peninsula, or neighboring countries. Primary disease cases, ie cases with no prior exposure to human cases occurred mainly in Saudi Arabia, but also in other countries such as the United Arab Emirates, Iran, Jordan, Qatar, Oman and Kuwait. During March 2012-March 2013 to more than 5 cases were reported on a monthly basis, the monthly number of April 2013 for about a year rose toapproximately to 10 to 20. In April and May 2014, occurred several major hospital outbreaks, so a week up to 100 new cases were reported. From June 2014, the number of new cases is approximately returned to the state before April 2014.
Many of the substances classified as sporadic (or the case) cases had contact with dromedaries, but a significant proportion of these primary cases is currently not explainable through a zoonotic source. Important for the global risk assessment - but also for Germany - is that there are as yet no evidence of sustained transmission in the general population. However, imported cases of the disease are possible at any time, since about 1 million people fly annually from the countries of the Arabian Peninsula to Germany. In Europe, imported cases were or secondary cases of imported cases in small numbers from Germany, France, Greece, Great Britain, Italy the Netherlands, Austria and Turkey announced. About imported cases (Algeria, Tunisia), North America (the was also from Africa United States ) and Asia (Malaysia, the Philippines) reported. As part of the world intensified surveillance because of pilgrimages to Saudi Arabia (Hajj and Umrah) individual laboratory-confirmed MERS cases were possibly identified.
End in May 2015 reported the health authorities of South Korea an outbreak, which dates back to an imported case of MERS. The patient had previously toured several countries on the Arabian Peninsula. A high-risk exposure during his trip was not known, therefore the diagnosis MERS was not initially contemplated. There are among medical staff, family members, co-patients and their relatives more than 150 other diseases, even deaths can be reported. One of the previously identified in South Korea contact persons traveled to China, was there tested positive and isolated. Both South Korea and China have taken very far-reaching control measures. Nevertheless, it should be noted that given the late diagnosis, the multiple situations with possible transfers, and the incubation period up to 14 days definitely still more cases are expected. New to this situation is the emergence of a widespread outbreak outside the Arabian Peninsula, as well as the occurrence of a secondary case in another third country (here China). At least in two cases was also an infection of the "third generation" confirmed, ie that an infected person from the index case has infected another person who had no contact with the index case. A basis for further infection chain is not so far (see situation to the WHO, see link below).
There is increasing scientific evidence that dromedaries are the source of the human, zoonotic infections. This results in part from the discovery that when a large proportion of camels from Arab countries, but also African countries, antibodies against MERS-CoV were found, and the virus itself could also be isolated in dromedaries. From stored samples from 1983 and 1984, respectively antibodies against MERS-CoV was detected in the majority of posts originating from Somalia or the Sudan camels. As part of an investigation of a diseased to MERS (and previously serologically negative) owner of a small Dromedarherde a MERS-CoV could be identified whose gene sequences corresponded to 100% with the virus of one of its diseased camels. This is regarded as conclusive evidence that at least in this situation, a dromedary has transmit the virus to a human. Finally, an increased risk was in those who in their work related to camels found for MERS infection than people who do not work with dromedaries.
With regard to the risk of transmission there are conflicting experiences.Although it has been described that the morbidity and infection rate is low in household contacts of primary cases, on the other hand, more, have some great, nosocomial outbreaks occurred.
Situation in Germany (change)
In Germany had occurred in March 2015 the third time a MERS-CoV case, as in the two preceding cases, the disease was brought by a who entered from the Arabian Peninsula patients. There was a 65 year old German, who had traveled to the United Arab Emirates and was treated at a hospital in Lower Saxony.According to a press release of the Lower Saxony Ministry of Social, Health and Equality patient had overcome the actual MERS infection. However, it was the beginning of June died of other, subsequent lung disease, according to the Ministry with (see link below). People with close contact with the patients were monitored by the competent public health authorities; there were no other cases.
Previously each one patient were treated in 2012 and 2013 from Qatar or from the United Arab Emirates in Germany, one of the two patients was discharged recovered, died other. The investigation of contacts in both cases had no evidence of secondary infections arising (Buchholz et al. , Euro Surveillance02/21/2013; Epidemiological Bulletin . No. 31/2013, see below for references).
The risk assessment and indications of the RKI for travelers and medical personnel remain unchanged.
...

http://www.rki.de/DE/Content/InfAZ/M/MERS_Coronavirus/MERS-CoV.html

Dear Sirs,
the 65-year-old, who had been infected in February in the Arabian Peninsula with the MERS virus, has now died in hospital in Ostercappeln. The share the Niels Stensen-Kliniken with. According to the hospital network of the patient had already overcome the actual MERS infection in Marienhospital Osnabr?ck. He died in the night of 6 June, another, subsequent lung disease. Infected, the 65-year-old had his journey probably visiting a pet market - it is believed that most dromedaries transfer the MERS virus.
"We regret the death of this patient very, our sympathy goes out to the families, who had hoped for an improvement in the condition and now have to cope with this great loss," said Lower Saxony's social and health minister Cornelia Rundt. In Osnabr?ck case was a transfer of MERS- virus be prevented to contact persons, the Minister sees this as a great success of the medical personnel and the authorities involved.
Currently a MERS infection wave in South Korea provides international concern;there diagnosis MERS was initially not considered in a patient. There are in South Korea under medical staff, family members, co-patients and their families more than a hundred other diseases, even deaths can be reported. One of the previously identified in South Korea contact persons traveled to China, was there tested positive and isolated.
Against this background, Minister Cornelia Rundt expressly praised the highly qualified and committed action by all those involved in the Osnabr?ck case: "The local players have taken this MERS-case seriously immediately, the hospital and the local health authority have the necessary protective measures such as the identification and isolation started suspicions. More than 200 people were examined for MERS, it fell ill no other person. Our thanks also go to the partners of the Ministry of Social Affairs as the country's public health department, the Robert Koch Institute and the University of Bonn. The example shows South Korea sadly that this coordinated management in terms of MERS is absolutely necessary. "
Travelers visiting the Arabian Peninsula, are particularly warned against contact with dromedaries or with funds emanating from these products. In Germany there is no risk of infection. The current wave of infection in South Korea has broken out after the return of an infected person from the Arabian Peninsula. The Robert Koch Institute monitors the development and informed as follows: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) has been known since April 2012. Clinically proven cases presenting at the beginning with an acute beginning, influenza-like illness. The incubation period is usually one to two weeks. In severe cases, a pneumonia may develop, which may turn into an acute respiratory distress syndrome. A frequent concomitant symptom is diarrhea; in severe cases even kidney failure may occur. Severe cases occur predominantly in persons with chronic medical conditions such as diabetes, cancer or immune suppression. Since the first appearance of MERS 2012 WHO reported 1,300 laboratory-confirmed cases, especially in the Arabian Peninsula, about 40% of the affected people of them died.

http://www.ms.niedersachsen.de/aktue...s--134542.html