Worldwide: 24 confirmed cases due to novel animal nCoV coronavirus - 16 fatalities - September 20, 2012 - May 2, 2013

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Re: Saudi Arabia, Qatar: 6 confirmed cases (2 fatal) due to novel animal coronavirus

Well, some of the reporting above is bad. WHO is now reporting 7 confirmed and 1 probable case, confirming the third case in the cluster:

http://www.flutrackers.com/forum/showthread.php?t=195697

They are also only reporting one death total, which must be the Saudi man in June, so all four cases in the cluster are still alive? How could they have made this error? We had multiple sources mention two fatalities in the cluster. And the case that they just confirmed was previously reported to have died.

Or is the latest WHO report the incorrect one?

[sharon sanders]

Re: Saudi Arabia, Qatar: 6 confirmed cases (2 fatal) due to novel animal coronavirus

Well, some of the reporting above is bad. WHO is now reporting 7 confirmed and 1 probable case, confirming the third case in the cluster:

http://www.flutrackers.com/forum/showthread.php?t=195697

They are also only reporting one death total, which must be the Saudi man in June, so all four cases in the cluster are still alive? How could they have made this error? We had multiple sources mention two fatalities in the cluster. And the case that they just confirmed was previously reported to have died.

Or is the latest WHO report the incorrect one?

Unknown.

The latest official WHO GAR report dated November 23 says 2 deaths:

"Of the 6 laboratory confirmed cases reported to WHO, 4 cases (including 2 deaths) are from Saudi Arabia and 2 cases are from Qatar."

http://www.who.int/csr/don/2012_11_23/en/index.html

[alert]

Re: Saudi Arabia, Qatar: 7 confirmed cases due to novel animal coronavirus - unclear number of fatalities

http://www.cidrap.umn.edu/cidrap/content/other/sars/news/nov2912corona.html

[snip]

Details on third case
A team of Saudi and British authors provided details on the third novel coronavirus case, which was first announced by Saudi authorities Nov 4. The 45-year-old patient was hospitalized for 22 days and needed breathing support and hemodialysis before his eventual recovery, according to the report.

The article describes the patient as a heavy smoker who has type 2 diabetes, a history of ischemic heart disease, and only one functioning kidney.

Three days before his illness onset, the man visited a farm near his home and had brief contact with farm animals. The report does not mention any illness among the animals. The man had not traveled outside Riyadh before his illness, but he had been in contact with one of his children, who had a mild cold.

The patient fell ill on Oct 9, was seriously ill by Oct 12, and was moved to an intensive care unit (ICU) the next day. He needed breathing assistance for several days, and he received dialysis treatments for renal failure from Oct 15 to 23. He was finally released from the hospital Nov 4.

The man tested negative for a wide range of viruses and bacterial pathogens. But respiratory specimens tested positive for the novel coronavirus upE gene in two labs, a Saudi Arabian health ministry lab in Jeddah and the UK Health Protection Agency lab in Birmingham. The virus was not found in the patient's stool, plasma, or serum specimens.

The authors sequenced small pieces of two of the coronavirus genes from this case and the first case, which involved a Saudi Arabian man who died in June. They found that the sequences were identical to one another and to the same gene fragments from the second novel coronavirus case (the Qatari patient in London).

The authors comment that exposure to farm animals was identified as a risk factor in the first novel coronavirus case, but add that such exposures appear to be "an insignificant risk factor for cases 2 and 3."

[Gert van der Hoek]

Re: Saudi Arabia, Qatar: 7 confirmed cases due to novel animal coronavirus - 3 fatalities

The WHO-document has been corrected:

"Of the seven confirmed cases, five developed acute renal failure and three of these died".

http://www.who.int/csr/disease/coronavirus_infections/InterimRevisedSurveillanceRecommendations_nCoVinfection_28Nov12u.pdf

As of 28 November 2012, seven confirmed and one probable case of novel coronavirus infection in humans are known to have occurred. These cases range in time from June through November 2012 and occurred in the areas around Jeddah and Riyadh of Saudi Arabia (which are about 850 km apart), and in Doha, Qatar. Infection with the virus appears to have been acquired locally in each of these situations. All of the patients were male but the significance of this is unknown.

The clinical picture in all cases was an acute respiratory infection presenting with signs and symptoms of pneumonia. Of the seven confirmed cases, five developed acute renal failure and three of these died. The remaining two confirmed cases had pneumonia that required intensive support, without renal failure, and recovered. Three of the seven confirmed cases and the one probable case all belong to the same family and were living in the same household.

[Treyfish]

Re: Saudi Arabia, Qatar: 7 confirmed cases due to novel animal coronavirus - 3 fatalities

Changing all the time.

According quoted Network (IRIN), a spokesman for the World Health Organization Thomas Glynn that and who said: It is based on our understanding of the virus so far, due to the strengthening of controls, we expect to report more cases, and confirm HIV infection. "
and added, "We also expect to see more cases in other countries.
explained that scientists organization working on a cause of the infection, and to ascertain whether the virus is transmitted from one person to another or not. http://dostor.org/%D8%A7%D9%84%D8%A3...A7%D8%B1%D8%B3

[Treyfish]

Re: Saudi Arabia, Qatar: 7 confirmed cases due to novel animal coronavirus - 3 fatalities

New SARS-related coronavirus claims a third life

The recommendations were revised two days later to say that five of the seven confirmed cases had ?developed acute renal failure and three of these died.?

According to Thomas, the surveillance recommendations are in the process of being updated with clarifications on the number of cases. ?Significant information? about the novel coronavirus will be announced on the WHO?s website, under the Disease Outbreak News section, Thomas said in an email Friday morning.

The WHO recommendations describe the clinical picture of the new coronavirus as an acute respiratory infection. All of the confirmed cases showed signs of pneumonia..
http://www.thestar.com/news/world/ar...s-a-third-life

[Treyfish]

Re: Saudi Arabia, Qatar: 7 confirmed cases due to novel animal coronavirus - 3 fatalities

Novel coronavirus infection - update

30 NOVEMBER 2012 - In addition to the fatal case of novel coronavirus in Saudi Arabia reported to WHO on 28 November, two fatal cases in Jordan have been reported to WHO today, bringing the total of laboratory-confirmed cases to nine.

The latest confirmed case from Saudi Arabia occurred in October 2012 and is from the family cluster of the two cases confirmed earlier.

The two cases from Jordan occurred in April 2012. At that time, a number of severe pneumonia cases occurred in the country and the Ministry of Health (MOH) Jordan promptly requested a WHO Collaborating Centre for Emerging and Re-emerging Infectious Diseases (NAMRU – 3) team to immediately assist in the laboratory investigation. The NAMRU-3 team went to Jordan and tested samples from this cluster of cases.

On 24 April 2012 the NAMRU-3 team informed the MOH that all samples had tested negative for known coronaviruses and other respiratory viruses. As the novel coronavirus had not yet been discovered, no specific tests for it were available.

In October 2012, after the discovery of the novel coronavirus, stored samples were sent by MOH Jordan to NAMRU-3. In November 2012 NAMRU-3 provided laboratory results that confirmed two cases of infection with the novel coronavirus.

The MOH Jordan has requested WHO assistance in investigating these infections. A mission from WHO Eastern Mediterranean Regional Office (EMRO) and headquarters arrived in Amman on 28 November 2012 to assist in further epidemiological surveillance and to strengthen the sentinel surveillance systems for severe acute respiratory infections (SARIs).

In summary, to date a total of nine laboratory-confirmed cases of infection with the novel coronavirus have been reported to WHO – five cases (including 3 deaths) from Saudi Arabia, two cases from Qatar and two cases (both fatal) from Jordan.http://www.who.int/csr/don/2012_11_30/en/index.html

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Re: Saudi Arabia, Qatar: 7 confirmed cases due to novel animal coronavirus - 3 fatalities

Amazing find, Treyfish. I have copied the article to the Jordan thread, and am in the process of moving it and renaming both threads.

It is unclear the status of the fatalities in Saudi Arabia at this point; by my count, there have now been 5 fatalities in 9 cases.

[Treyfish]

Re: Saudi Arabia, Qatar, Jordan: 9 confirmed cases due to novel animal coronavirus - 3-5 fatalities

At least 5 dead. The way the reporting is, we should hear of 5 more within a month or 2

[alert]

Re: Saudi Arabia, Qatar, Jordan: 9 confirmed cases due to novel animal coronavirus - 3-5 fatalities

At least 5 dead. The way the reporting is, we should hear of 5 more within a month or 2

Let us not forget that there are at least nine additional hospitalized contacts in the Jordan outbreak, that should now be considered probable infections.

This also moves the earliest onset in the outbreak back from June to early April, meaning this virus has been around for nearly 8 months, longer than the entire 2003 SARS outbreak.

[Giuseppe]

Re: Saudi Arabia, Qatar, Jordan: 9 confirmed cases due to novel animal coronavirus - 5 fatalities

It should be noted that SARS CoV was poorly transmissible, thus it was contained so easily.

This new nCoV has an unknown Reproductive Number as well as mode of transmission.

In hospital setting, it is likely that viral particles went airborne through aerosolization instruments or through biological fluids.

It remains highly questionable that the Jordan institutional outbreak was almost completely missed by Western media outlets despite local news coverage and the panic it caused.

[Treyfish]

Re: Saudi Arabia, Qatar, Jordan: 9 confirmed cases due to novel animal coronavirus - 5 fatalities

WHO confirms 2 more fatal cases of new virus in Jordan, possible virus spread between people
..The two cases date back to April and are part of a cluster of a dozen people who fell sick in Zarqa, Jordan. Officials are investigating whether the 10 other people sick in Zarqa also were infected and how it might have spread. Other cases of the virus have been spotted in Saudi Arabia and Qatar.

WHO doesn?t know exactly how the virus spreads but said it couldn?t exclude the possibility it was being transmitted from person to person.http://www.washingtonpost.com/world/...80_story.html?

AS MANY THAT WERE SICK THEN, THERE IS NO QUESTION IT WAS H2H imo

[Treyfish]

Re: Saudi Arabia, Qatar, Jordan: 9 confirmed cases due to novel animal coronavirus - 5 fatalities

WHO: 2 MORE CASES OF NEW VIRUS IN JORDAN

LONDON (AP) -- International health officials have confirmed two more fatal cases of a mysterious respiratory virus in the Middle East.

The virus has so far sickened nine people and killed five of them. The virus is related to SARS, which killed some 800 people in a global epidemic in 2003.

The two cases date back to April and are part of a cluster of a dozen people who fell sick in Zarqa, Jordan. Officials are investigating whether the 10 other people sick in Zarqa also were infected and how it might have spread. Other cases of the virus have been spotted in Saudi Arabia and Qatar.

WHO doesn't know exactly how the virus spreads but said it couldn't exclude the possibility it was being transmitted from person to person.

http://hosted.ap.org/dynamic/stories...MPLATE=DEFAULT

[Treyfish]

Re: Saudi Arabia, Qatar, Jordan: 9 confirmed cases due to novel animal coronavirus - 5 fatalities

WHO confirms 2 more fatal cases of new virus in Jordan, possible virus spread between people
By: Maria Cheng, The Associated Press
LONDON - International health officials have confirmed two more fatal cases of a mysterious respiratory virus in the Middle East.
The virus has so far sickened nine people and killed five of them. The new disease is a coronavirus related to SARS, which killed some 800 people in a global epidemic in 2003, and belongs to a family of viruses that most often causes the common cold.
The two cases date back to April and are part of a cluster of a dozen people, mostly health workers, who fell sick in an intensive care unit at a hospital in Zarqa, Jordan. Officials are investigating whether the 10 other people who grew sick in Zarqa also were infected and how the virus might have spread.
"It's too early to say whether human-to-human transmission occurred or not, but we certainly can't rule it out," said WHO spokesman Gregory Hartl.
One of the Jordanian cases was a 40-year-old female. All of the other patients to date have been men. The new virus has so far been identified in patients from Saudi Arabia and Qatar.
Scientists haven't found any links between the sporadic cases of the coronavirus so far, first detected in September. "We don't know how the virus gets around and there are more questions than answers right now," Hartl said.
Several of the patients sickened by the new coronavirus have had rapid kidney failure and others have suffered severe pneumonia and respiratory illnesses. The virus is most closely related to a bat virus and scientists are also considering whether bats or animals like camels or goats are a possible source of infection.
Scientists are also considering whether fruit contaminated by animal droppings may have spread the virus.
Still, not all of the cases had contact with animals and WHO said it was possible the virus was spread between humans in the Jordan hospital and in a cluster of cases in Saudi Arabia, where four members of the same family fell ill and two died.
WHO says the virus is probably more widespread than just the Middle East and recommended that countries test any people with unexplained pneumonia.http://www.winnipegfreepress.com/bre...181561141.html

[Treyfish]

Re: Saudi Arabia, Qatar, Jordan: 9 confirmed cases due to novel animal coronavirus - 5 fatalities

The WHO said the two latest deaths were in Jordan. The disease had previously been detected only in Saudi Arabia and Qatar, although one patient was transferred to the UK for treatment.

It brings the total number of cases of the infection to nine.

There may also be evidence of human to human spread of the virus.

It causes pneumonia and sometimes kidney failure.

There was a series of severe cases of pneumonia in Jordan earlier in the year. However, the novel coronavirus had not been discovered at the time so did not appear in routine tests...
..How readily the virus spreads will be important for assessing how great a threat it poses.

The WHO said that, unlike Sars, the new coronavirus, "does not appear to transmit easily between people".

However, it warns that two clusters in Saudi Arabia and Jordan, "raise the possibility of limited human-to-human transmission" or they could have been exposed to the same source of the infection.http://www.bbc.co.uk/news/health-20554760