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Mexico - Possible case of Tamiflu Resistance and also Possible 222 (225) Change to H1N1 Virus
Possible case of mutation of A H1N1
By Gabriela Gonzalez, Wednesday, February 10th, 2010
They believe that the 275 mutation may have occurred for one patient, who was in the hospital of the IMSS
NUEVO LAREDO .- The mutation 222 and 275 of the influenza A virus H1N1, which caused health specialists again ignite the hot spots to the suspicion that this mutation is recorded in patients who are affected by the H1N1 strain A 2009.
222 is the mutation rate refers to patients with influenza A H1N1, which show no resistance to antiviral traditionally fight this disease.
The type 275 of the virus occurs in patients who are resistant to oseltamivir (brand name Tamiflu) and has already been reported in isolation in several countries.
Locally, although not confirmed officially, it is suspected that the 275 mutation has already been registered in a patient, who in the last quarter of 2009, was admitted to the Hospital de Zona No. 11 del IMSS.
Dr. Angel Contreras Gutierrez, the hospital epidemiologist, explained that this case occurred in less unresponsive to treatment, within the space of 12 hours on average is recorded in patients affected by influenza A H1N1.
"This patient was taken from its cultivation (sample) and sent to INDRE and there we said it was susceptible mycobacterial, while it was changed by one traditional medicine for injection and responded favorably, this medicine is used in very serious and delicate as it is also a control treatment, "he said.
Contreras Gutierrez said that while decreased considerably currently suspected influenza A H1N1, with this mutation of the virus, the first protocol of actions to be performed is a constant monitoring of each new suspected cases.
"Since we started the year until this week five, were two to a case which had been reported as suspicious of influenza A H1N1 in terms of seven days, but now they will have to make monitoring by which to enact if the patient shows resistance to drugs, "he said.
Of the suspected cases of human influenza, he said, the latest occurred last week in a child who spent time in Laredo, Texas.
The epidemiologist said that even with this new warning issued by the Ministry of Health by these mutations of the A H1N1, the IMSS is considered ready to face the new cases of this virus.
"To cope with the influenza virus, we have thousand 500 treatments of Tamiflu, but we also have the Senavivir, and what's new and effective Panavivir, this is an injectable solution that applies only to patients who are resistant to traditional medicine that are considered very serious cases.
"With these mutations, people should not be alarmed and should continue to expectation, fighting this disease now even with the implementation of the A H1N1 vaccine and following the hygiene measures to prevent universal," he said.
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