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Mexico uses genomic technology in new wave of influenza A/H1N1

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  • Mexico uses genomic technology in new wave of influenza A/H1N1

    Source: http://www.jornada.unam.mx/2009/07/1...ticle=035n1soc

    Singapore scientists analyzed platform and chip samples collected during the emergency
    Mexico uses genomic technology in new wave of influenza A/H1N1

    Bilateral support to prevent complications such as that caused dozens of deaths


    Directors of the Genomics Institute of Singapore are visiting Mexico to make available to health authorities the technology platform that performs the complete genetic sequencing of influenza A/H1N1 virus, determine its origin, mutations and eventual resistance to antivirals.

    The above, so that the complications that the country faced during the pandemic, with the death of young adults and the possibility, not yet confirmed, that these deaths are caused by infection of the additional strain A/H1N1 , can be avoided in the second "wave" of infection, which is expected to happen from next October.

    T. Edison Liu, executive director of the Genomics Institute of the Asian nation, whom he had led the scientific team that made four years ago against the epidemic of severe acute respiratory syndrome (SARS), explained that the new tool, in just 24 hours information can be A/H1N1 virus, which would be helpful if during the winter when the expected increase in the number of sick-presented with different situations that occur between March and May 2009.

    That is explained in an interview, which was observed in hospitals where patients do not respond to therapy and complications were not provided by physicians. In this regard, Gerardo Jimenez Sanchez, director of the National Institute of Genomic Medicine (INMEGEN), commented that the new strain of influenza contains between 13 thousand and 15 thousand words. While in Mexico we have the technology to record and identify the type of influenza virus that affects humans, the scientists proposed that Singapore is facing the possibility that the strain changes, in the shortest time possible have verification of that mutation, and even the exact site where it occurred.

    "Patch" of three viruses

    Liu said that viruses are transformed by nature. He recalled that the A/H1N1 strain, responsible for the pandemic is a "patch" of three influenza viruses, which can be identified with laboratory equipment available, which was acquired by Mexico and began to operate for about 10 days after of the health emergency declared. However, mutations go unnoticed for these instruments, the scientist said.

    Experts from Singapore also brought a chip that identifies 700 varieties of viruses that affect humans and that may be present in people with the A/H1N1 strain. Has the advantage of requiring only collect the sample or nasal pharyngeal exudate and put in these chips, which are popular with high-tech equipment. Eventually she says could pinpoint the cause of complications and to avoid a high mortality.

    Scientists in Singapore have brought both technological tools, and since they arrived last Monday, was tested by INMEGEN with samples supplied by the Institute of Epidemiological Diagnosis and Reference (Indre).

    Jim?nez S?nchez said that this Friday will be the results, as the level of virus concentration and samples can be analyzed with tools in Asia. It also ensured that the technology has identified that this is a new strain, among others.

    The scientist stressed that Singapore has invested in technology development, but "has no samples or the experience of Mexico in the management of the pandemic." That is the basis for collaboration between the two nations for this project. Liu reported that an agreement of support between the Institute of Genomic Medicine of Singapore and Mexico as part of which the team of six doctors and scientists from the Asian country this week visiting the Indre, the National Institutes of Respiratory Diseases (INER) of Medical Sciences and Nutrition (INCMN) of Pediatrics (INP) and the National Center of Epidemiological Surveillance and Disease Control.

    The manager said they are interested in learning from the Mexican experience with the influenza A/H1N1, particularly on the most serious cases, and will jointly prepare for the second "wave" of the pandemic.

    Moreover, the Health Secretariat (SSA) reported that before the outbreaks of the disease in Chiapas and Yucatan, was sent brigades and epidemiological expertise to help prevent the spread of the virus.

    In a statement, said that in Yucatan infection was stabilized, but in Chiapas are recorded daily between 100 and 130 new cases.

  • #2
    Re: Mexico uses genomic technology in new wave of influenza A/H1N1

    > make available to health authorities the technology platform that performs the complete
    > genetic sequencing

    good !
    If health authorities have it, there is a chance that we will get (parts of) it too, after some delay.
    But apparantly they only want to use it for th 2nd wave, not for the old samples,
    not to explore the origin and whether it may happen again.

    >[Singapore} "has no samples ...

    ohh

    > agreement of support

    ...and secrecy, presumably
    I'm interested in expert panflu damage estimates
    my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

    Comment


    • #3
      Re: Mexico uses genomic technology in new wave of influenza A/H1N1

      Anything is better than nothing,
      so if they realy wants to slow the second wave, come on.

      The problem is they worldwide continue to not slow the first wave, don't provide real time vaccines, and antivirals mostly late or only if confirmed.

      Comment

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