Mexico - 4 new outbreaks of highly pathogenic avian influenza H7N3 in birds (OIE, March 3, 2016)

[Pathfinder]

Highly pathogenic avian influenza, Mexico

Information received on 03/03/2016 from Dr Joaqu?n Braulio Delgadillo ?lvarez, Director General de Salud Animal, Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA) Secretar?a de Agricultura, Ganader?a, Desarrollo Rural, Pesca y Alimentaci?n, Ministerio de Agricultura, Ganader?a, Desarrollo rural, Pesca y Alimentaci?n, Mexico, Mexico

Summary Report type Follow-up report No. 1 Date of start of the event 09/03/2015 Date of confirmation of the event 09/03/2015 Report date 03/03/2016 Date submitted to OIE 03/03/2016 Reason for notification Reoccurrence of a listed disease Date of previous occurrence 09/2014 Manifestation of disease Clinical disease Causal agent Highly pathogenic avian influenza virus Serotype H7N3 Nature of diagnosis Clinical, Laboratory (basic) This event pertains to a defined zone within the country Related reports Immediate notification (08/04/2015) Follow-up report No. 1 (03/03/2016)

New outbreaks (4)

Outbreak 1 Tehuacan, Tehuacan, PUEBLA Date of start of the outbreak 14/08/2015 Outbreak status Resolved (17/08/2015) Epidemiological unit Farm Affected animals Species Susceptible Cases Deaths Destroyed Slaughtered Birds 145 20 15 130 0 Affected population Commercial layers

Outbreak 2 San Ignacio Cerro Gordo, San Ignacio Cerro Gordo, JALISCO Date of start of the outbreak 22/10/2015 Outbreak status Resolved (25/10/2015) Epidemiological unit Backyard Affected animals Species Susceptible Cases Deaths Destroyed Slaughtered Birds 3100 3095 3095 5 0 Affected population Backyard poultry

Outbreak 3 Lagos de Moreno, Lagos de Moreno, JALISCO Date of start of the outbreak 26/01/2016 Outbreak status Continuing (or date resolved not provided) Epidemiological unit Farm Affected animals Species Susceptible Cases Deaths Destroyed Slaughtered Birds 413086 15 0 0 0 Affected population Commercial layers

Outbreak 4 Tochtepec, Tochtepec, PUEBLA Date of start of the outbreak 15/02/2016 Outbreak status Resolved (22/02/2016) Epidemiological unit Farm Affected animals Species Susceptible Cases Deaths Destroyed Slaughtered Birds 119016 1000 1000 118016 0 Affected population Commercial layers

Summary of outbreaks Total outbreaks: 4 Total animals affected Species Susceptible Cases Deaths Destroyed Slaughtered Birds 535347 4130 4110 118151 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Birds 0.77% 0.77% 99.52% 22.84% *Removed from the susceptible population through death, destruction and/or slaughter

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments After 27/03/2015, fallowing of the affected production unit in the state of Oaxaca was carried out for 21 days and subsequently sentinel birds were introduced, these same birds were tested on 23 April and 4 May 2015, results were negative. Sentinel birds were destroyed and finally the quarantine on the production unit was lifted on 12 May 12 2015.Regarding the outbreak of the state of Puebla (backyard), all the birds and the risk materials (eggs, food, poultry litter and packaging) were destroyed on 27/03/2015 by burial. Cleaning and disinfection of the premises and fallowing for 21 days were performed. The quarantine on the production unit was lifted on 22 September 2015.In the framework of active surveillance at national level, highly pathogenic avian influenza (HPAI) subtype H7N3 was identified with viral isolation in a production unit of layers located in Lagos de Moreno, Jalisco. The birds showed no clinical signs suggestive of avian influenza, possibly as they were part of a vaccination programme. Therefore to confirm the diagnosis, the intravenous pathogenicity index test (IVPI) was performed and a title of 2.85 was confirmed. .The farm has been put under quarantine, the epidemiological investigation started as well as the diagnosis of situation in the perifocal area. So far, five additional positive viral isolates have identified in farms located in the municipality of Encarnacion de Diaz, however they belong to the same company of the index outbreak. Confirmation of these diagnoses by the official laboratory of SENASICA is awaited. Following a notification from a producer, highly pathogenic avian influenza (HPAI) subtype H7N3 was identified by positive virus isolation as well as the intravenous pathogenicity index (IVPI) test with a title of 2.92 in an agricultural production unit located in the municipality of Tochpec, Puebla. The farm has been put under quarantine and the corresponding epidemiological investigation has begun.More information about these health events will be provided to this organization as advances obtained in the investigation

Control measures Measures applied Movement control inside the country Screening Disinfection / Disinfestation Quarantine Zoning Vaccination prohibited No treatment of affected animals Measures to be applied Stamping out Official disposal of carcasses, by-products and waste

Diagnostic test results Laboratory name and type Species Test Test date Result Level 3 Biosecurity Laboratory, SENASICA (National laboratory) Birds intravenous pathogenicity index (IVPI) test 29/01/2016 Positive Level 3 Biosecurity Laboratory, SENASICA (National laboratory) Birds intravenous pathogenicity index (IVPI) test 29/02/2016 Positive Level 3 Biosecurity Laboratory, SENASICA (National laboratory) Birds virus isolation 26/01/2016 Positive Level 3 Biosecurity Laboratory, SENASICA (National laboratory) Birds virus isolation 15/02/2016 Positive Level 3 Biosecurity Laboratory, SENASICA (National laboratory) Birds virus isolation 09/03/2015 Positive

Future Reporting The event is continuing. Weekly follow-up reports will be submitted.

.../

http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review?page_refer=MapFullEventReport&reportid=19565