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Circulating vaccine-derived poliovirus type 2 (cVDPV2) - Algeria - WHO

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  • Circulating vaccine-derived poliovirus type 2 (cVDPV2) - Algeria - WHO

    13 September 2022

    Outbreak at a glance

    On 8 July 2022, WHO was notified of a case of circulating vaccine-derived poliovirus type 2 (cVDPV2) with acute flaccid paralysis (AFP) from Tamanrasset province, southern Algeria. This represents the first cVDPV2 case identified in the country. Local public health authorities are conducting a field investigation, and an active search for additional AFP cases; a reactive Immunization campaign is also planned.

    Description of the outbreak

    On 8 July 2022, a case of circulating vaccine-derived poliovirus type 2 (cVDPV2) in Algeria was notified to WHO through the Global Polio Laboratory Network (GPLN). The case is a child under two years old from Tamanrasset province, southern Algeria, with onset of acute flaccid paralysis (AFP) on 11 April 2022. Stool specimens tested positive for cVDPV2 by the Pasteur Institute of Algeria and were confirmed by Pasteur Institute of Paris. Genomic sequencing analysis indicates that the isolated virus is genetically linked to a virus previously isolated in Kano, Nigeria. The child had not received any polio vaccine doses and has no history of travel outside Tamanrasset province.

    This represents the first cVDPV2 case identified in Algeria, where, according to the 2021 WHO-UNICEF immunization coverage estimates, Pol3 (3rd dose of polio-containing vaccine) coverage was 91% and IPV1 (one dose of the inactivated polio vaccine) coverage was 94%.

    ... WHO’s International travel and health recommends that all travellers to polio-affected areas be fully vaccinated against polio. Residents (and visitors for more than 4 weeks) from infected areas should receive an additional dose of oral polio vaccine (OPV) or inactivated polio vaccine (IPV) within four weeks to 12 months of travel.

    Based on the advice of an Emergency Committee convened under the International Health Regulations (2005), the risk of international spread of poliovirus remains a Public Health Emergency of International Concern (PHEIC). Countries affected by poliovirus transmission are subject to Temporary Recommendations. To comply with the Temporary Recommendations issued under the PHEIC, any country infected by poliovirus should declare the outbreak as a national public health emergency, ensure the vaccination of residents and long-term visitors and restrict at the point of departure travel of individuals, who have not been vaccinated or cannot prove the vaccination status.

    On 8 July 2022, WHO was notified of a case of circulating vaccine-derived poliovirus type 2 (cVDPV2) with acute flaccid paralysis (AFP) from Tamanrasset province, southern Algeria. This represents the first cVDPV2 case identified in the country. Local public health authorities are conducting a field investigation, and an active search for additional AFP cases; a reactive Immunization campaign is also planned.


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