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Situational assessment for SARS-CoV-2 variant V-23AUG-01 (BA.2.86). Updated 1 September 2023 - UK Health Security Agency

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  • Situational assessment for SARS-CoV-2 variant V-23AUG-01 (BA.2.86). Updated 1 September 2023 - UK Health Security Agency

    Updated 1 September 2023
    Applies to England

    Part 1. Context and UK cases

    As of 10am, 31 August 2023, 25 BA.2.86 genome sequences are available on the international genomic data-sharing platform, GISAID. These originate in 8 different countries:
    • 10 in Denmark
    • 4 in Sweden
    • 4 in USA
    • 2 in Portugal
    • 2 in South Africa
    • 1 in Canada
    • 1 in Israel
    • 1 in UK
    Two further UK cases, one in England and one in Scotland, have been identified and genome sequence data will be available on GISAID shortly. This is a dynamic situation changing daily.

    Sample dates, where known, range from 24 July 2023 (Denmark, South Africa) to 22 August 2023 (USA) (Figure 1).

    The first UK case was reported in the previous risk assessment, published 18 August 2023. All UK cases were identified through hospital testing and have no known recent travel history through routinely collected data.

    The first UK case was mildly unwell and the second UK case (England) did not have respiratory symptoms. The third UK case (Scotland) was symptomatic. The samples for the 2 new cases were sequenced through routine surveillance of hospital test-positive cases.

    A number of additional countries have also made formal or informal announcements of BA.2.86 detection in wastewater. There is no internationally consistent repository for wastewater genomic data. ...


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