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Indonesia - Dengue down with 77% in local trial with Wolbachia infected mosquitoes

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  • Indonesia - Dengue down with 77% in local trial with Wolbachia infected mosquitoes

    Breakthrough In Eliminating Dengue, Other Mosquito-Borne Diseases

    UNIVERSITY OF CALIFORNIA - BERKELEY 23 SEPTEMBER 2020
    A 27-month trial in Indonesia of a unique method of mosquito control shows that the strategy can reduce the incidence of dengue.


    A 27-month trial in Indonesia of a unique method of mosquito control shows that the strategy can reduce the incidence of dengue — a mosquito-borne viral disease of the tropics that threatens nearly half the world’s population — by 77%.

    The method, which employs Aedes aegypti mosquitoes infected by bacteria called Wolbachia, effectively prevents dengue-infected mosquitoes from passing on the virus when they bite people. The study, the preliminary results of which were released today (Wednesday, Aug. 26), looked only at dengue, but the mosquito control strategy may likely work for other viruses carried by A. aegypti mosquitoes, including Zika, chikungunya and yellow fever.

    “It is a huge breakthrough,” said Nicholas Jewell, a Professor of the Graduate School at the University of California, Berkeley, who designed the study and led the statistical analysis. “We’ve now shown that it works in one city. If this can be replicated and used widely, it could eradicate dengue from several parts of the world for many years.”

    More than two years after completion of mosquito releases in the city of Yogyakarta, on the island of Java, Wolbachia remains at a very high level in the local mosquito population, the researchers noted.

    “This exciting result of the trial is a great success for the people of Yogyakarta,” said Adi Utarini from the University of Gadjah Mada in Indonesia, co-principal Investigator of the trial. “Indonesia has 7 million dengue cases every year. This trial result shows the significant impact the Wolbachia method can have in reducing dengue in urban populations.”
    Release of mosquitoes infected with a bacterium called Wolbachia slashes transmission of dengue by more than 75%
    “Addressing chronic disease is an issue of human rights – that must be our call to arms"
    Richard Horton, Editor-in-Chief The Lancet

    ~~~~ Twitter:@GertvanderHoek ~~~ GertvanderHoek@gmail.com ~~~
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