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New Israeli drug cured 29 of 30 moderate/serious COVID cases in days in Phase one trial — hospital

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  • New Israeli drug cured 29 of 30 moderate/serious COVID cases in days in Phase one trial — hospital

    Source: https://www.timesofisrael.com/new-is...days-hospital/


    New Israeli drug cured 29 of 30 moderate/serious COVID cases in days — hospital
    Medicine developed at Ichilov moderates immune response, helps prevent deadly cytokine storm, researchers say; 29 of 30 phase 1 trial patients left hospital within 3-5 days
    By TOI staff Today, 3:29 pm 9

    A new coronavirus treatment being developed at Tel Aviv’s Ichilov Medical Center has successfully completed phase 1 trials and appears to have helped numerous moderate-to-serious cases of COVID-19 quickly recover from the disease, the hospital said Friday.

    Hailing a “huge breakthrough,” the hospital said Prof. Nadir Arber’s EXO-CD24 substance had been administered to 30 patients whose conditions were moderate or worse, and all 30 recovered — 29 of them within three to five days.

    The medicine fights the cytokine storm — a potentially lethal immune overreaction to the coronavirus infection that is believed to be responsible for much of the deaths associated with the disease.

    It uses exosomes — tiny carrier sacs that shuttle materials between cells — to deliver a protein called CD24 to the lungs, which Arber has spent decades researching.

    “This protein is located on the surface of cells and has a well known and important role in regulating the immune system,” said researcher Shiran Shapira of Arber’s lab.

    The protein helps calm down the immune system and curb the storm...
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