India Influenza 2015: 2,990 confirmed fatalities

[Ronan Kelly]

h/t tetano
Infect Dis Obstet Gynecol. 2016; 2016: 1248470.
Published online 2016 Jan 19. doi: 10.1155/2016/1248470

PMCID: PMC4745581

Influenza Illness in Pregnant Indian Women: A Cross-Sectional Study

Parvaiz A. Koul, 1 , * Nargis K. Bali, 2 Hyder Mir, 1 Farhat Jabeen, 3 and Abida Ahmad 4

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Abstract

Data about burden of influenza in pregnancy in India are scant. In order to assess the contribution of influenza to acute respiratory illness (ARI) in pregnancy, 266 north Indian pregnant females with febrile ARI were studied from December 2014 to May 2015. Twin nasopharyngeal/oropharyngeal swabs were obtained and tested for influenza viruses by RT-PCR. Fifty (18.8%) patients tested positive for influenza (A/H1N1pdm09 in 41, A/H3N2 in 8, and influenza B Yamagata in 1). Rigors, headache, and a family history of ARI were significantly more frequent in influenza positive patients. Oseltamivir and supportive therapy were administered to all confirmed cases. Nine influenza positive cases needed hospitalization for their respiratory illness, and 5 developed respiratory failure. Of these, 4 (3 in third trimester) succumbed to their illness. We conclude that influenza viruses are a cause of significant morbidity and mortality among pregnant females with ARI in north India. As such, appropriate preventive strategies of influenza vaccination and early initiation of antiviral therapy during illness are stressed.Abstract
Data about burden of influenza in pregnancy in India are scant. In order to assess the contribution of influenza to acute respiratory illness (ARI) in pregnancy, 266 north Indian pregnant females with febrile ARI were studied from December 2014 to May 2015. Twin nasopharyngeal/oropharyngeal swabs were obtained and tested for influenza viruses by RT-PCR. Fifty (18.8%) patients tested positive for influenza (A/H1N1pdm09 in 41, A/H3N2 in 8, and influenza B Yamagata in 1). Rigors, headache, and a family history of ARI were significantly more frequent in influenza positive patients. Oseltamivir and supportive therapy were administered to all confirmed cases. Nine influenza positive cases needed hospitalization for their respiratory illness, and 5 developed respiratory failure. Of these, 4 (3 in third trimester) succumbed to their illness. We conclude that influenza viruses are a cause of significant morbidity and mortality among pregnant females with ARI in north India. As such, appropriate preventive strategies of influenza vaccination and early initiation of antiviral therapy during illness are stressed.

full paper available from; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745581/

[Ronan Kelly]

h/t tetano Influenza A(H1N1)pdm09 cases in sub-Himalayan region, 2014-2015 India

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Indian J Pathol Microbiol. 2016 Jan-Mar;59(1):63-5. doi: 10.4103/0377-4929.178222.
Influenza A(H1N1)pdm09 cases in sub-Himalayan region, 2014-2015 India.

Sharma P¹, Gupta S, Singh D, Verma S, Kanga A.
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Abstract

Current influenza A(H1N1)pdm09 strain severely involved many parts of the country. The study was conducted to analyze the clinicoepidemiological trend of influenza A(H1N1)pdm09 cases from October 2014 to March 2015. Samples processing was done as per the Center for Disease Control guidelines. A total of 333 specimens were processed out of which influenza A(H1N1)pdm09 constituted 24% (81) of total, 5% (18) cases were seasonal influenza A virus strains. Mean age group involved was 49 years with case fatality rate of 20%. Patients died were 63% males and 44% had comorbidities, and among them, 38% patients died within 24 h of hospitalization. The mean age of comorbid patients who died was 59 years; whereas the mean age of patients died having no co-morbidities was 41 years (P < 0.005). Mortality was seen among 81% (13) of patients who were on ventilator support. Added mortality in specific human group demands continuous surveillance monitoring followed by the detection of mutation, even in susceptible animal population.


PMID: 26960638 [PubMed - in process]

[Ronan Kelly]

http://pib.nic.in/newsite/erelease.aspx?relid=154039

Annexure I Influenza A H1N1 (Swine Flu) ? Year-wise for affected States/UTs (2015-2016)
S. No.	State	Jan, 2015- 31st Dec, 2015		1st Jan,2016- 30th Oct,2016
Cases	Deaths	Cases	Deaths
1.	Andaman & Nicobar	4	0	0	0
2.	Andhra Pradesh	258	36	5	4
3.	Assam	31	4	0	0
4.	Bihar	352	6	0	0
5.	Chandigarh(UT)	23	7	6	0
6.	Chhattisgarh	239	53	6	4
7.	Dadra & Nagar Haveli	26	6	1	0
8.	Daman & Diu	5	1	0	0
9.	Delhi	4307	12	192	7
10.	Goa	193	19	3	0
11.	Gujarat	7180	517	411	55
12.	Haryana	433	58	68	5
13.	Himachal Pradesh	123	27	14	5
14.	Jammu & Kashmir	495	20	2	0
15.	Jharkhand	16	6	1	1
16.	Karnataka	3565	94	86	0
17.	Kerala	928	76	21	0
18.	Madhya Pradesh	2445	367	38	12
19.	Maharashtra	8583	905	80	25
20.	Manipur	5	2	0	0
21.	Meghalaya	1	0	0	0
22.	Mizoram	4	0	0	0
23.	Nagaland	4	0	0	0
24.	Odisha	76	13	1	0
25.	Pondicherry	57	4	0	0
26.	Punjab	300	61	177	64
27.	Rajasthan	6858	472	196	43
28.	Tamil Nadu	898	29	64	1
29	Telangana*	2956	100	126	8
30.	Uttarakhand	105	15	20	5
31.	Uttar Pradesh	1578	50	122	16
32.	West Bengal	544	30	7	2
Cumulative Total		42592	2990	1647	257