Study reports recrudescent wave of influenza in Kashmir (Times of India, October 22 2013)

[Giuseppe]

[Source: Times of India, full text: (LINK).]


Study reports recrudescent wave of influenza in Kashmir

October 22 2013


A study published in a scientific journal PLOS ONE has reported about the recrudescent wave of influenza A/H1N1pdm09 in the winter of 2012-2013 in Kashmir and said there was need for a continued surveillance in order to understand the pattern of circulation and its clinical cost in the region.

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[Ronan Kelly]

Re: Study reports recrudescent wave of influenza in Kashmir (Times of India, October 22 2013)

Recrudescent Wave of A/H1N1pdm09 Influenza Viruses in Winter 2012-2013 in Kashmir, India
SEPTEMBER 26, 2013 ? RESEARCH

AUTHORS
Parvaiz Koul
Umar Khan
Khursheed Bhat
Siddhartha Saha
Shobha Broor
Renu Lal
Mandeep Chadha
ABSTRACT

Some parts of world, including India observed a recrudescent wave of influenza A/H1N1pdm09 in 2012. We undertook a study to examine the circulating influenza strains, their clinical association and antigenic characteristics to understand the recrudescent wave of A/H1N1pdm09 from November 26, 2012 to Feb 28, 2013 in Kashmir, India. Of the 751 patients (545 outpatient and 206 hospitalized) presenting with acute respiratory infection at a tertiary care hospital in Srinagar; 184 (24.5%) tested positive for influenza. Further type and subtype analysis revealed that 106 (58%) were influenza A (H1N1pdm09 =105, H3N2=1) and 78 (42%) were influenza B. The influenza positive cases had a higher frequency of chills, nasal discharge, sore throat, body aches and headache, compared to influenza negative cases. Of the 206 patients hospitalized for pneumonia/acute respiratory distress syndrome or an exacerbation of an underlying lung disease, 34 (16.5%) tested positive for influenza (22 for H1N1pdm09, 11 for influenza B). All influenza-positive patients received oseltamivir and while most patients responded well to antiviral therapy and supportive care, 6 patients (4 with H1N1pdm09 and 2 with influenza B) patients died of progressive respiratory failure and multi-organ dysfunction. Following a period of minimal circulation, H1N1pdm09 re-emerged in Kashmir in 2012-2013, causing serious illness and fatalities. As such the healthcare administrators and policy planners need to be wary and monitor the situation closely.
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http://currents.plos.org/outbreaks/article/resurgence-of-ah1n1pdm09-influenza-viruses-in-winter-2012-2013in-kashmir-india/