India malaria deaths hugely underestimated, says report

[Ronan Kelly]

20 October 2010 Last updated at 19:28 ET
India malaria deaths hugely underestimated, says report
By Ania Lichtarowicz

Health reporter, BBC News


Malaria can be cured easily if diagnosed and treated quickly The number of people dying from malaria in India has been hugely underestimated, according to new research.

The data, published in the Lancet, suggests there are 13 times more malaria deaths in India than the World Health Organization (WHO) estimates.

The authors conclude that more than 200,000 deaths per year are caused by malaria.
The WHO said the estimate produced by this study appears too high.
continues at;

http://www.bbc.co.uk/news/health-11588212

[Ronan Kelly]

Re: India malaria deaths hugely underestimated, says report

The Lancet, Early Online Publication, 21 October 2010doi:10.1016/S0140-6736(10)60831-8Cite or Link Using DOI
Adult and child malaria mortality in India: a nationally representative mortality survey

Neeraj Dhingra MD a b, Prof Prabhat Jha DPhil b , Vinod P Sharma DPhil c, Alan A Cohen PhD b, Raju M Jotkar MD b d, Peter S Rodriguez MSA b, Diego G Bassani PhD b, Wilson Suraweera MSc b, Ramanan Laxminarayan PhD e, Prof Richard Peto FRS f, for the Million Death Study Collaborators?

Summary
Background
National malaria death rates are difficult to assess because reliably diagnosed malaria is likely to be cured, and deaths in the community from undiagnosed malaria could be misattributed in retrospective enquiries to other febrile causes of death, or vice-versa. We aimed to estimate plausible ranges of malaria mortality in India, the most populous country where the disease remains common.

Methods
Full-time non-medical field workers interviewed families or other respondents about each of 122 000 deaths during 2001?03 in 6671 randomly selected areas of India, obtaining a half-page narrative plus answers to specific questions about the severity and course of any fevers. Each field report was sent to two of 130 trained physicians, who independently coded underlying causes, with discrepancies resolved either via anonymous reconciliation or adjudication.

Findings
Of all coded deaths at ages 1 month to 70 years, 2681 (3?6%) of 75 342 were attributed to malaria. Of these, 2419 (90%) were in rural areas and 2311 (86%) were not in any health-care facility. Death rates attributed to malaria correlated geographically with local malaria transmission ratesderived independently from the Indian malaria control programme. The adjudicated results show 205 000 malaria deaths per year in India before age 70 years (55 000 in early childhood, 30 000 at ages 5?14 years, 120 000 at ages 15?69 years); 1?8% cumulative probability of death from malaria before age 70 years. Plausible lower and upper bounds (on the basis of only the initial coding) were 125 000?277 000. Malaria accounted for a substantial minority of about 1?3 million unattended rural fever deaths attributed to infectious diseases in people younger than 70 years.

Interpretation
Despite uncertainty as to which unattended febrile deaths are from malaria, even the lower bound greatly exceeds the WHO estimate of only 15 000 malaria deaths per year in India (5000 early childhood, 10 000 thereafter). This low estimate should be reconsidered, as should the low WHO estimate of adult malaria deaths worldwide.

Funding
US National Institutes of Health, Canadian Institute of Health Research, Li Ka Shing Knowledge Institute.

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)60831-8/abstract