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India - Media reports bird flu death (H5N1); AIIMS-Delhi staff placed under isolation - July 20, 2021 - sample confirmed positive for A/H5 and Type B Victoria lineage - H5N1

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  • India - Media reports bird flu death (H5N1); AIIMS-Delhi staff placed under isolation - July 20, 2021 - sample confirmed positive for A/H5 and Type B Victoria lineage - H5N1

    An 11-year-old boy who was undergoing treatment for Avian Influenza has died at the All India Institute of Medical Sciences (AIIMS) in New Delhi. This is the first bird flu death recorded in the country since the beginning of this year.

    The entire staff at AIIMS, New Delhi, has been placed in isolation as a preventative measure.

    According to the World Health Organisation (WHO), human cases of bird flu (Avian Influenza) occur " occasionally" but when they do happen, the mortality rate is about 60 per cent.

    Bird flu outbreaks were reported across the country earlier this year, including in Haryana where experts detected the H5N8 subtype of the Avian Influenza virus. This strain is not known to infect humans.

    The central government had sounded an alert when cases of bird flu were confirmed in Delhi and at least ten states, including Kerala, Rajasthan, Madhya Pradesh, Himachal Pradesh, Gujarat, Maharashtra and Haryana. Culling of birds was carried out in large numbers across the country in a bid to counter the spread of infection.

  • #2

    Bird flu death at AIIMS: 11-year-old is first recorded casualty this year

    People who have come in close contact with infected birds, dead or alive, can contract the H5N1 flu but according to the WHO, it does not usually spread from person to person.(This is wrong. It can spread person-to-person. This is why staff is isolated. ss)

    An 11-year-old boy died of H5N1 avian influenza Tuesday, making this the first recorded death due to the bird flu in India this year.

    An AIIMS official stated that the boy had been admitted to the hospital on July 2 and that he died on Tuesday. The official added that all staff who had been in contact with the patient are under isolation.


    People who have come in close contact with infected birds, dead or alive, can contract the H5N1 flu but according to the WHO, it does not usually spread from person to person.


    • #3
      I added this case to our list because there are two generally reliable media reporting it:

      FluTrackers 2016+ Global H5N1 Human Cases List (with link to previous years)


      W.H.O. case list

      Click image for larger version  Name:	whoh5n1cumlist.JPG Views:	2 Size:	149.8 KB ID:	919880


      • #5
        12-year-old boy suffering from bird flu succumbs at AIIMS in Delhi

        Human-to-human transmission of bird flu rare, no need to panic: AIIMS chief

        ?Addressing chronic disease is an issue of human rights ? that must be our call to arms"
        Richard Horton, Editor-in-Chief The Lancet

        ~~~~ Twitter:@GertvanderHoek ~~~ ~~~


        • #6
          Ministry of Health and Family Welfare

          IDSP State Surveillance Unit (SSU), Haryana to initiate an epidemiological investigation into the first documented human case of Bird Flu

          Close contacts of the patient under surveillance for any symptoms

          No suspected case of bird flu in the area

          Awareness building activities being carried out to report any other symptomatic case

          Posted On: 21 JUL 2021 8:10PM by PIB Delhi

          An 11 year old child has been reported as the first human case of H5Nx from Gurugram, Haryana.

          The male child was diagnosed with AML in Paediatrics department, AIIMS, Delhi on June 2021. He developed symptoms of fever, cough, coryza, and breathing difficulty, soon after induction therapy for AML. He was diagnosed as AML with febrile neutropenia with pneumonia and shock, which progressed to ARDS. He was admitted to AIIMS, New Delhi on 2nd July, 2021. The boy suffered from multi organ dysfunction and died on 12 July 2021.

          Department of Microbiology AIIMS received the Bronchoalveolar lavage (BAL) for respiratory panel testing on 7 and 11 July 2021. The sample has tested Positive for both Influenza A and Influenza B. It was also negative for SARS COV-2 and other respiratory viruses. Subtyping for Influenza A remained inconclusive with available reagents for H1N1 and H3N2 at AIIMS. So, the samples were sent to NIV on 13 July, 2021

          At NIV, both the samples were tested for Influenza A and Influenza B along with Influenza A seasonal (H1N1, H1N1 pdm09 and H3N2), non-seasonal avian subtypes (H5, H7, H9 and H10) by Real time PCR. The result showed that the sample is positive for A/H5 and Type B Victoria lineage. Whole genome sequencing and Virus isolation is in process.

          NCDC, Delhi received information on Friday July 16th, 2021 from AIIMS, Delhi along with a lab report from NIV Pune. The information was communicated to the IDSP State Surveillance Unit (SSU), Haryana to initiate an epidemiological investigation into the case. The matter was also reported to the Animal Husbandry Department. A team from NCDC composed of Epidemiologists & Microbiologists was constituted and the team immediately visited AIIMS, New Delhi and Gurugram for undertaking an epidemiological assessment. The State health department and the animal husbandry department officials are also involved in the investigation.

          Based on the available information, the team of doctors and nurses treating the patient are being monitored since 16th July 2021 for development of any influenza like illness with no one reported symptomatic till date. Contact tracing was undertaken and family members, close contacts and health care workers are under close surveillance. None of the close contacts have any symptoms. Contact tracing, an active search for any symptomatic case has been carried out in the hospital and area where the case resided. IEC activities carried out for the general public with an advice to report any symptomatic case to the health authorities. There are no symptomatic individuals in the area at present.

          The Animal Husbandry Department has not found any suspected cases of bird flu in the area and has enhanced surveillance in a 10 km zone as a precautionary measure. Further, epidemiological investigation by NCDC, involving animal husbandry department and State government surveillance unit, is underway and appropriate public health measures have been instituted.



          HFW-Bird Flu case/21st July2021-5

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          • #7
            The boy had acute myloid leukemia:


            • #8
              Thank you to everyone who remembers us with a mention and link. We really appreciate it since we are all volunteers.

              We will remember who supports our efforts by referring to us.


              • #9

                Human infection with avian influenza A(H5N1) ー India

                16 August 2021

                On 21 July 2021, the National IHR focal point of India notified WHO of one human case of avian Influenza A(H5N1) from Haryana state, northern India. This is the first reported case of human infection of influenza A(H5N1) virus in India.
                The patient was a boy under 18 years of age with a recently diagnosed underlying illness in June 2021. Shortly after immunosuppressive treatment was initiated at the hospital, he presented with fever, cough, upper respiratory symptoms and breathing difficulty on 12 June. His condition progressed to acute respiratory distress syndrome and he was mechanically ventilated but died on 12 July. In the past year, the boy resided with a family member who owned a butchery in Haryana state. Based on initial investigations, there were no reports of poultry sickness or deaths from a nearby poultry farm in the village where he resided. The source of infection is unknown at this time and none of his family members have shown similar symptoms thus far.
                On 7 and 11 July 2021, respiratory samples from the patient tested positive by reverse transcriptase -polymerase chain reaction (RT-PCR) at the All India Institute of Medical Science hospital for influenza A and influenza B viruses but negative for SARS-CoV-2 and other respiratory viruses. On 13 July, the samples were sent to National Institute of Virology, a WHO reference laboratory for influenza, for subtyping. Samples were tested for seasonal viruses of influenza A and influenza B, as well as avian influenza subtypes H5, H7, H9 and H10 by RT-PCR. On 15 July, the samples tested positive for influenza A(H5N1) and influenza B/Victoria lineage viruses. Whole genome sequencing and virus isolation is ongoing.

                Public health response

                Local and national health authorities have taken the following monitoring, prevention and control measures:
                • Conducting further epidemiological investigation on the origin of infection of the case, including a multidisciplinary rapid response team (comprising public health and animal health officials) supporting the state of Haryana;
                • Strengthened surveillance, including enhanced monitoring of febrile cases (house to house surveys for fever surveillance conducted by health care workers) within a 10 km radius of the patient’s residence;
                • Disinfected the patient’s residence and the surrounding environment;
                • Directed all health institutions in the district to report any suspected cases of human infection with avian influenza;
                • Closely traced and managed contacts of the case, including health care workers at the medical facility where the case was provided care;
                • Performed risk communication activities to heighten public awareness, including for personal protective measures;
                • Conducted animal surveillance by the animal husbandry department.

                WHO risk assessment

                Available information and initial field investigations suggest that no additional cases have been suspected, indicating a low likelihood of human-to-human transmission. Further sporadic cases of human infection with avian influenza A(H5) viruses may be reported because these viruses have been occasionally detected in poultry populations in India. The risk assessment will be reviewed as necessary, should further epidemiological or virological information become available.
                India has reported outbreaks of avian influenza A(H5N1) in poultry farms every year since it was first reported in a poultry farm in Maharashtra State in February 2006. In January and February 2021, Haryana state reported an outbreak of avian influenza A(H5N8) in Panchkula district, which severely affected poultry in the area. In that outbreak, samples collected from birds from four poultry farms tested positive for avian influenza A(H5N8).
                Should infected individuals from affected areas travel internationally, their infection may be detected in another country during travel or after arrival. If this were to occur, further community level spread is considered unlikely as this virus has not acquired the ability to transmit easily among humans.

                WHO advice

                The detection of this case does not change current WHO recommendations on public health measures and surveillance of influenza. The primary risk factor for human infection with avian influenza is direct or indirect exposure to infected poultry (live or dead) or wildlife, as well as contaminated environments such as live bird markets. Additional risk factors include slaughtering, defeathering, handling carcasses of infected poultry, and preparing poultry for consumption, especially in household settings.
                As at all times, the public should avoid contact with high-risk environments such as live animal markets/farms and live poultry, or surfaces that might be contaminated by poultry or bird faeces. Hand hygiene with frequent handwashing with soap and water or use of alcohol-based hand sanitizer is recommended.
                Good food safety practices such as keeping cooking environments clean, separating raw and cooked food, and cooking food thoroughly, should also be followed. There is no evidence to suggest that influenza A(H5), A(H7N9) or other avian influenza viruses can be transmitted to humans through properly cooked poultry. There is no epidemiological evidence to suggest that people have been infected with avian influenza by consumption of eggs or egg products. However, eggs from areas with outbreaks in poultry should not be consumed raw or partially cooked (with runny yolk).
                Health care workers preforming aerosol-generating procedures should use airborne precautions. Standard contact and droplet precautions and appropriate personal protective equipment should be made available and used during epidemics.
                Due to the constantly evolving nature of influenza viruses, WHO continues to stress the importance of global surveillance to detect virological, epidemiological and clinical changes associated with circulating influenza viruses that may affect human or animal health, as well as timely sharing of viruses to inform risk assessments.
                In the case of a confirmed or suspected human infection caused by a novel influenza virus with pandemic potential, including avian influenza or variant viruses, a thorough epidemiologic investigation should be conducted (even while awaiting the confirmatory laboratory results) on the history of exposure to animals, of travel, and contact tracing. The epidemiologic investigation should include early identification of unusual respiratory events that could signal human-to-human transmission of the novel virus. Additionally, clinical samples collected from the time and place that the case occurred should be tested and sent to a WHO Collaboration Centre for further characterization.
                All human infections caused by a novel influenza subtype are notifiable under the International Health Regulations [IHR (2005)] and State Parties to the IHR (2005) are required to immediately notify WHO of any laboratory-confirmed case of a recent human infection caused by an influenza A virus with the potential to cause a pandemic. Evidence of illness is not required for this report. WHO does not recommend any specific measures for travellers, and advises against the application of any travel or trade restrictions in relation to this event based on the currently available information.

                Further information