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H1N1 Russia 2008 (Tamiflu Resistant)

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  • H1N1 Russia 2008 (Tamiflu Resistant)

    LOCUS FJ456890 484 bp cRNA linear VRL 30-NOV-2008
    DEFINITION Influenza A virus (A/Grodno/108/2008(H1N1)) segment 6 neuraminidase
    (NA) gene, partial cds.
    ACCESSION FJ456890
    VERSION FJ456890.1 GI:214011894
    KEYWORDS .
    SOURCE Influenza A virus (A/Grodno/108/2008(H1N1))
    ORGANISM Influenza A virus (A/Grodno/108/2008(H1N1))
    Viruses; ssRNA negative-strand viruses; Orthomyxoviridae;
    Influenzavirus A.
    REFERENCE 1 (bases 1 to 484)
    AUTHORS Shmialiova,N., Gribkova,N., Yatsyshina,S. and Minenko,A.
    TITLE Oseltamivir and remantadine sensitivity of influenza A viruses
    isolated in Belarus
    JOURNAL Med Zhurnal (2009) In press
    REFERENCE 2 (bases 1 to 484)
    AUTHORS Shmialiova,N., Gribkova,N., Yatsyshina,S. and Minenko,A.
    TITLE Direct Submission
    JOURNAL Submitted (01-NOV-2008) Influenza and Influenza-Like Illnesses,
    Research Institute for Epidemiology and Microbiology, Filimonova
    Street, 23, Minsk 220114, Belarus
    FEATURES Location/Qualifiers
    source 1..484
    /organism="Influenza A virus (A/Grodno/108/2008(H1N1))"
    /mol_type="viral cRNA"
    /strain="A/Grodno/108/2008"
    /serotype="H1N1"
    /host="Homo sapiens"
    /db_xref="taxon:574257"
    /segment="6"
    /country="Belarus"
    /collection_date="23-Jan-2008"
    gene <1..>484
    /gene="NA"
    CDS <1..>484
    /gene="NA"
    /codon_start=3
    /product="neuraminidase"
    /protein_id="ACJ61694.1"
    /db_xref="GI:214011895"
    /translation="GWLTIGISGPDNGAVAVLKYNGIITGTIKSWKKQILR TQESECV
    CMNGSCFTIMTDGPSNKAASYKIFKIEKGKVTKSIELNAPNFYYEECSCY PDTGIVMC
    VCRDNWHGSNRPWVSFNQNLDYQIGYICSGVFGDNPRPEDGEGSCNPVTV DGANGVKG"
    ORIGIN
    1 tgggctggtt aacaatcgga atttctggtc cagacaatgg agctgtggct gtactaaaat
    61 acaacggaat aataactgga accataaaaa gttggaaaaa gcaaatatta agaacacaag
    121 agtctgaatg tgtctgtatg aacgggtcat gtttcaccat aatgaccgat ggcccgagta
    181 ataaggccgc ctcgtacaaa attttcaaga tcgaaaaggg gaaggttact aaatcaatag
    241 agttgaatgc acccaatttt tattatgagg aatgctcctg ttacccagac actggcatag
    301 tgatgtgtgt atgcagggac aactggcatg gttcaaatcg accttgggtg tcttttaatc
    361 aaaacttgga ttatcaaata ggatacatct gcagtggagt gtttggtgac aatccgcgtc
    421 ccgaagatgg agagggcagc tgcaatccag tgactgttga tggagcaaac ggagtaaaag
    481 ggtt

  • #2
    Re: H1N1 Russia 2008 (Tamiflu Resistant)

    Partial NA sequence (484 BP) is IDENTICAL to the following:

    gb|FJ456890.1| Influenza A virus (A/Grodno/108/2008(H1N1)) se... 894 0.0
    gb|FJ445031.1| Influenza A virus (A/England/557/2007(H1N1)) s... 894 0.0
    gb|FJ445029.1| Influenza A virus (A/England/26/2008(H1N1)) se... 894 0.0
    gb|FJ445020.1| Influenza A virus (A/Netherlands/159/2008(H1N1... 894 0.0
    gb|FJ403583.1| Influenza A virus (A/Denmark/27/2007(H1N1)) se... 894 0.0
    gb|FJ403582.1| Influenza A virus (A/Luxembourg/116/2008(H1N1)... 894 0.0
    gb|FJ403580.1| Influenza A virus (A/Austria/406109/2008(H1N1)... 894 0.0
    gb|FJ403575.1| Influenza A virus (A/Parma/34/08(H1N1)) segmen... 894 0.0
    gb|FJ403574.1| Influenza A virus (A/Geneva/9296/2008(H1N1)) s... 894 0.0
    gb|FJ403570.1| Influenza A virus (A/Canarias/RR-2915/2007(H1N... 894 0.0
    gb|FJ403568.1| Influenza A virus (A/Berlin/47/2008(H1N1)) seg... 894 0.0
    gb|FJ403563.1| Influenza A virus (A/Slovenia/123/2008(H1N1)) ... 894 0.0
    gb|FJ403562.1| Influenza A virus (A/Belgium/G257/08(H1N1)) se... 894 0.0
    gb|FJ403561.1| Influenza A virus (A/Kiev/313/2008(H1N1)) segm... 894 0.0
    gb|FJ403558.1| Influenza A virus (A/Lisbon/3/2008(H1N1)) segm... 894 0.0
    gb|FJ403555.1| Influenza A virus (A/Lyon/1337/07(H1N1)) segme... 894 0.0
    gb|FJ403554.1| Influenza A virus (A/Athens/41/2008(H1N1)) seg... 894 0.0
    gb|FJ403548.1| Influenza A virus (A/Bucuresti/229/2008(H1N1))... 894 0.0
    gb|FJ380948.1| Influenza A virus (A/Finland/11/2008(H1N1)) se... 894 0.0
    gb|FJ360527.1| Influenza A virus (A/Ireland/69/2008(H1N1)) se... 894 0.0
    gb|FJ360526.1| Influenza A virus (A/Ireland/68/2008(H1N1)) se... 894 0.0
    gb|FJ360525.1| Influenza A virus (A/Ireland/24/2008(H1N1)) se... 894 0.0
    gb|FJ360524.1| Influenza A virus (A/Ireland/27/2008(H1N1)) se... 894 0.0
    gb|FJ360523.1| Influenza A virus (A/Ireland/43/2008(N1)) segm... 894 0.0
    gb|FJ227687.1| Influenza A virus (A/HongKong/942/2008(H1N1)) ... 894 0.0
    gb|EU914908.1| Influenza A virus (A/Johannesburg/45/2008(H1N1... 894 0.0
    gb|EU914907.1| Influenza A virus (A/Johannesburg/36/2008(H1N1... 894 0.0
    gb|EU914905.1| Influenza A virus (A/Johannesburg/33/2008(H1N1... 894 0.0
    gb|EU914904.1| Influenza A virus (A/Johannesburg/14/2008(H1N1... 894 0.0
    gb|EU914903.1| Influenza A virus (A/Johannesburg/21/2008(H1N1... 894 0.0
    gb|EU914902.1| Influenza A virus (A/CapeTown/26/2008(H1N1)) n... 894 0.0
    gb|EU685788.1| Influenza A virus (A/Paris/1170/2008(H1N1)) ne... 894 0.0
    gb|EU551826.1| Influenza A virus (A/Paris/749/2007(H1N1)) neu... 894 0.0
    gb|EU551824.1| Influenza A virus (A/Paris/847/2007(H1N1)) neu... 894 0.0
    gb|EU551813.1| Influenza A virus (A/Paris/1208/2008(H1N1)) ne... 894 0.0
    gb|EU551812.1| Influenza A virus (A/Paris/1154/2008(H1N1)) ne... 894 0.0
    gb|EU551811.1| Influenza A virus (A/Paris/341/2007(H1N1)) neu... 894 0.0
    gb|EU551810.1| Influenza A virus (A/Paris/910/2007(H1N1)) neu... 894 0.0
    gb|EU551809.1| Influenza A virus (A/Paris/644/2007(H1N1)) neu... 894 0.0
    gb|EU887035.1| Influenza A virus (A/South Carolina/01/2008(H1... 894 0.0
    gb|EU851980.1| Influenza A virus (A/Hawaii/01/2008(H1N1)) seg... 894 0.0
    gb|EU779643.1| Influenza A virus (A/New Jersey/10/2008(H1N1))... 894 0.0
    gb|EU702755.1| Influenza A virus (A/Hong Kong/17/2008(H1N1)) ... 894 0.0
    gb|EU716587.1| Influenza A virus (A/Washington/01/2008(H1N1))... 894 0.0
    gb|EU624316.1| Influenza A virus (A/England/557/2007(H1N1)) s... 894 0.0
    gb|EU567009.1| Influenza A virus (A/Arizona/13/2007(H1N1)) se... 894 0.0
    gb|EU567006.1| Influenza A virus (A/Arizona/14/2007(H1N1)) se... 894 0.0
    gb|EU566999.1| Influenza A virus (A/Wisconsin/01/2008(H1N1)) ... 894 0.0
    gb|EU566987.1| Influenza A virus (A/New Jersey/20/2007(H1N1))... 894 0.0
    gb|EU566983.1| Influenza A virus (A/New Jersey/05/2008(H1N1))... 894 0.0
    gb|EU566968.1| Influenza A virus (A/Arizona/15/2007(H1N1)) se... 894 0.0
    gb|EU516148.1| Influenza A virus (A/New Jersey/15/2007(H1N1))... 894 0.0

    Comment


    • #3
      Re: H1N1 Russia 2008 (Tamiflu Resistant)

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      <SCRIPT language=JavaScript1.2><!-- var Menu218848684 = [ ["UseLocalConfig", "jsmenu3Config", "", ""], ["Protein" , "window.top.location='/sites/entrez?Db=protein&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_protein&LinkReadableName=Protein&IdsFromR esult=218848684&ordinalpos=3&itool=EntrezSystem2.P Entrez.Nuccore.Sequence_ResultsPanel.Sequence_RVDo cSum' ", "", ""], ["Taxonomy" , "window.top.location='/sites/entrez?Db=taxonomy&DbFrom=nuccore&Cmd=Link&LinkNam e=nuccore_taxonomy&LinkReadableName=Taxonomy&IdsFr omResult=218848684&ordinalpos=3&itool=EntrezSystem 2.PEntrez.Nuccore.Sequence_ResultsPanel.Sequence_R VDocSum' ", "", ""], ["Related Sequences" , "window.top.location='/sites/entrez?Db=nuccore&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_nuccore&LinkReadableName=Related%20Sequen ces&IdsFromResult=218848684&ordinalpos=3&itool=Ent rezSystem2.PEntrez.Nuccore.Sequence_ResultsPanel.S equence_RVDocSum' ", "", ""] ] --></SCRIPT>Links</TD></TR><TR><TD style="PADDING-LEFT: 2.8em" vAlign=top align=left colSpan=3>Influenza A virus (A/Grodno/163/2008(H1N1)) segment 6 neuraminidase (NA) gene, partial cds
      gi|218848684|gb|FJ573481.1|[218848684]
      </TD></TR></TBODY></TABLE><!--docsumok 218848682 218848682 1 0 617-->
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      Reports<SCRIPT language=JavaScript1.2><!--var PopUpMenu2_LocalConfig_Reports218848682 = [ ["TitleText","Reports"]];var Reports218848682 = [ ["UseLocalConfig","Reports218848682","",""], ["ASN.1","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=as n'","",""], ["XML","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=xm l'","",""], ["Summary","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=do csum'","",""], ["Brief","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=br ief'","",""], ["FASTA","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=fa sta'","",""], ["TinySeq XML","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=fa sta_xml'","",""], ["GenBank","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=gb '","",""], ["INSDSeq XML","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=gb c_xml'","",""], ["GenBank(Full)","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=gb withparts'","",""], ["GI List","window.top.location='/entrez/viewer.fcgi?list_uids=218848682&db=nuccore&dopt=gi '","",""], ["Graphic","window.top.location='?cmd=Show&doptcmdl =graph&db=nuccore&term=FJ573480'","",""], ["Revision History","window.top.location='/entrez/sutils/girevhist.cgi?val=FJ573480'","",""]]--></SCRIPT> </TD><TD vAlign=top align=right>
      <SCRIPT language=JavaScript1.2><!-- var Menu218848682 = [ ["UseLocalConfig", "jsmenu3Config", "", ""], ["Protein" , "window.top.location='/sites/entrez?Db=protein&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_protein&LinkReadableName=Protein&IdsFromR esult=218848682&ordinalpos=4&itool=EntrezSystem2.P Entrez.Nuccore.Sequence_ResultsPanel.Sequence_RVDo cSum' ", "", ""], ["Taxonomy" , "window.top.location='/sites/entrez?Db=taxonomy&DbFrom=nuccore&Cmd=Link&LinkNam e=nuccore_taxonomy&LinkReadableName=Taxonomy&IdsFr omResult=218848682&ordinalpos=4&itool=EntrezSystem 2.PEntrez.Nuccore.Sequence_ResultsPanel.Sequence_R VDocSum' ", "", ""], ["Related Sequences" , "window.top.location='/sites/entrez?Db=nuccore&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_nuccore&LinkReadableName=Related%20Sequen ces&IdsFromResult=218848682&ordinalpos=4&itool=Ent rezSystem2.PEntrez.Nuccore.Sequence_ResultsPanel.S equence_RVDocSum' ", "", ""] ] --></SCRIPT>Links</TD></TR><TR><TD style="PADDING-LEFT: 2.8em" vAlign=top align=left colSpan=3>Influenza A virus (A/Minsk/211/2008(H1N1)) segment 6 neuraminidase (NA) gene, partial cds
      gi|218848682|gb|FJ573480.1|[218848682]
      </TD></TR></TBODY></TABLE></DT></DL>
      <!--docsumok 218848680 218848680 1 0 638--><DL><DT><TABLE cellPadding=0 width="100%"><TBODY><TR><TD style="WHITE-SPACE: nowrap" vAlign=top width="20%"><INPUT id=UidCheckBox type=checkbox value=218848680 name=EntrezSystem2.PEntrez.Nuccore.Sequence_Result sPanel.Sequence_RVDocSum.uid sid="5">5: FJ573479</TD><TD vAlign=top align=left>
      Reports<SCRIPT language=JavaScript1.2><!--var PopUpMenu2_LocalConfig_Reports218848680 = [ ["TitleText","Reports"]];var Reports218848680 = [ ["UseLocalConfig","Reports218848680","",""], ["ASN.1","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=as n'","",""], ["XML","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=xm l'","",""], ["Summary","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=do csum'","",""], ["Brief","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=br ief'","",""], ["FASTA","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=fa sta'","",""], ["TinySeq XML","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=fa sta_xml'","",""], ["GenBank","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=gb '","",""], ["INSDSeq XML","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=gb c_xml'","",""], ["GenBank(Full)","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=gb withparts'","",""], ["GI List","window.top.location='/entrez/viewer.fcgi?list_uids=218848680&db=nuccore&dopt=gi '","",""], ["Graphic","window.top.location='?cmd=Show&doptcmdl =graph&db=nuccore&term=FJ573479'","",""], ["Revision History","window.top.location='/entrez/sutils/girevhist.cgi?val=FJ573479'","",""]]--></SCRIPT> </TD><TD vAlign=top align=right>
      <SCRIPT language=JavaScript1.2><!-- var Menu218848680 = [ ["UseLocalConfig", "jsmenu3Config", "", ""], ["Protein" , "window.top.location='/sites/entrez?Db=protein&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_protein&LinkReadableName=Protein&IdsFromR esult=218848680&ordinalpos=5&itool=EntrezSystem2.P Entrez.Nuccore.Sequence_ResultsPanel.Sequence_RVDo cSum' ", "", ""], ["Taxonomy" , "window.top.location='/sites/entrez?Db=taxonomy&DbFrom=nuccore&Cmd=Link&LinkNam e=nuccore_taxonomy&LinkReadableName=Taxonomy&IdsFr omResult=218848680&ordinalpos=5&itool=EntrezSystem 2.PEntrez.Nuccore.Sequence_ResultsPanel.Sequence_R VDocSum' ", "", ""], ["Related Sequences" , "window.top.location='/sites/entrez?Db=nuccore&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_nuccore&LinkReadableName=Related%20Sequen ces&IdsFromResult=218848680&ordinalpos=5&itool=Ent rezSystem2.PEntrez.Nuccore.Sequence_ResultsPanel.S equence_RVDocSum' ", "", ""] ] --></SCRIPT>Links</TD></TR><TR><TD style="PADDING-LEFT: 2.8em" vAlign=top align=left colSpan=3>Influenza A virus (A/Minsk/142/2008(H1N1)) segment 6 neuraminidase (NA) gene, partial cds
      gi|218848680|gb|FJ573479.1|[218848680]
      </TD></TR></TBODY></TABLE></DT></DL>
      <!--docsumok 218848678 218848678 1 0 638--><DL><DT><TABLE cellPadding=0 width="100%"><TBODY><TR><TD style="WHITE-SPACE: nowrap" vAlign=top width="20%"><INPUT id=UidCheckBox type=checkbox value=218848678 name=EntrezSystem2.PEntrez.Nuccore.Sequence_Result sPanel.Sequence_RVDocSum.uid sid="6">6: FJ573478</TD><TD vAlign=top align=left>
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      <SCRIPT language=JavaScript1.2><!-- var Menu218848678 = [ ["UseLocalConfig", "jsmenu3Config", "", ""], ["Protein" , "window.top.location='/sites/entrez?Db=protein&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_protein&LinkReadableName=Protein&IdsFromR esult=218848678&ordinalpos=6&itool=EntrezSystem2.P Entrez.Nuccore.Sequence_ResultsPanel.Sequence_RVDo cSum' ", "", ""], ["Taxonomy" , "window.top.location='/sites/entrez?Db=taxonomy&DbFrom=nuccore&Cmd=Link&LinkNam e=nuccore_taxonomy&LinkReadableName=Taxonomy&IdsFr omResult=218848678&ordinalpos=6&itool=EntrezSystem 2.PEntrez.Nuccore.Sequence_ResultsPanel.Sequence_R VDocSum' ", "", ""], ["Related Sequences" , "window.top.location='/sites/entrez?Db=nuccore&DbFrom=nuccore&Cmd=Link&LinkName =nuccore_nuccore&LinkReadableName=Related%20Sequen ces&IdsFromResult=218848678&ordinalpos=6&itool=Ent rezSystem2.PEntrez.Nuccore.Sequence_ResultsPanel.S equence_RVDocSum' ", "", ""] ] --></SCRIPT>Links</TD></TR><TR><TD style="PADDING-LEFT: 2.8em" vAlign=top align=left colSpan=3>Influenza A virus (A/Minsk/124/2008(H1N1)) segment 6 neuraminidase (NA) gene, partial cds
      gi|218848678|gb|FJ573478.1|[218848678] </TD></TR></TBODY></TABLE></DT></DL>

      Comment


      • #4
        Re: H1N1 Russia 2008 (Tamiflu Resistant)

        All have H274Y and related to the earlier release.

        Comment

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