strange sequences from Helsinki, 2013

similar to the vaccine strain from 1997 in some segments
but that's not all. Swine triple reassortant,
some segments like temporary seasonal flu, others (8)
just distant to any H3N2


closest neighbors from my list of human and swine H3N2-viruses:

Code:
 30 >KF805633,A/Helsinki/716/2013,2013/02/16,Finland,H3N2
  6: 27, 57, 13,  0,  4,  3, 57,129   A/Sydney/5/1997,1997//,Australia,H3N2
 16:134, 37,158, 39,164, 16,120, 77   A/Sw/Index/triple-reassortant/1998(H3N2)
 26: 53, 75, 31, 62, 33, 51, 51,137   Index/32g12f1.c2,10-37

 31 >KF805641,A/Helsinki/798/2013,2013/02/20,Finland,H3N2
  6: 24, 57, 17,  0, 15,  3, 40,107   A/Sydney/5/1997,1997//,Australia,H3N2
 16:136, 37,157, 39,169, 16,111, 97   A/Sw/Index/triple-reassortant/1998(H3N2)
 26: 49, 75, 32, 62, 27, 51, 31,103   Index/32g12f1.c2,10-37

 32 >KF805649,A/Helsinki/823/2013,2013/02/21,Finland,H3N2
  6: 37, 53, 46,  2, 35,  7, 27, 88   A/Sydney/5/1997,1997//,Australia,H3N2
 16:130, 36,149, 41,172, 20,111,116   A/Sw/Index/triple-reassortant/1998(H3N2)
 25: 53, 71, 36, 59,  8, 47, 22, 87   A/Czech Republic/121/2012,2012/03/06,Czech Republic
 13: 49, 68, 38, 51,  9, 44, 23, 87   Index/2009/Egypt/Iowa
 11: 47, 65, 42, 45, 12, 39, 22, 83   Index/Brisbane-like/2007
 26: 54, 71, 36, 61,  9, 48, 21, 90   Index/32g12f1.c2,10-37

 33 >KF805657,A/Helsinki/824/2013,2013/02/21,Finland,H3N2
 25: 11, 61, 10, 14,  4,  4, 22, 13   A/Czech Republic/121/2012,2012/03/06,Czech Republic
 16:152, 35,162, 90,176, 53,111,162   A/Sw/Index/triple-reassortant/1998(H3N2)
 26: 11, 61, 10, 11,  5,  4, 19, 14   Index/32g12f1.c2,10-37
 11: 17, 55, 18, 27,  9, 16, 20, 10   Index/Brisbane-like/2007

 34 >KF805665,A/Helsinki/879/2013,2013/02/24,Finland,H3N2
 26:  6,  2,  6,  3,  4,  4,  0,  2   Index/32g12f1.c2,10-37
 25:  6,  3,  5,  6,  3,  4,  3,  3   A/Czech Republic/121/2012,2012/03/06,Czech Republic

 35 >KF805673,A/Helsinki/897/2013,2013/02/26,Finland,H3N2
  6: 39, 54, 14,  0,  0,  0, 77,119   A/Sydney/5/1997,1997//,Australia,H3N2
 16:124, 34,159, 39,168, 14,130, 88   A/Sw/Index/triple-reassortant/1998(H3N2)
 25: 60, 72, 32, 61, 32, 53, 69,122   A/Czech Republic/121/2012,2012/03/06,Czech Republic

 36 >KF805681,A/Helsinki/941/2013,2013/02/27,Finland,H3N2
  6: 25, 54, 29,  7, 30, 21, 31, 79   A/Sydney/5/1997,1997//,Australia,H3N2
  5: 41, 53, 42, 38, 37, 45, 35, 81   1989//,7852,CHN,A/Beijing/353/89
 26: 36, 72, 27, 59, 14, 34, 27, 78   Index/32g12f1.c2,10-37
 25: 35, 72, 28, 58, 13, 33, 28, 77   A/Czech Republic/121/2012,2012/03/06,Czech Republic
 10: 33, 67, 29, 45, 16, 39, 30, 73   2007/02/06,14278,AUS,A/Brisbane/10/07

 37 >KF805689,A/Helsinki/942/2013,2013/02/27,Finland,H3N2
 25: 12, 67,  6, 26,  4,  7, 16, 30   A/Czech Republic/121/2012,2012/03/06,Czech Republic
 16:151, 35,163, 79,176, 50,109,151   A/Sw/Index/triple-reassortant/1998(H3N2)
 26: 12, 68,  7, 24,  5,  7, 13, 32   Index/32g12f1.c2,10-37
 11: 17, 62, 15, 34,  9, 17, 14, 28   Index/Brisbane-like/2007

 38 >KF805697,A/Helsinki/951/2013,2013/03/01,Finland,H3N2
 26:  3,  1,  6,  7,  5,  5,  2,  3   Index/32g12f1.c2,10-37


------------------------------------------------------
 40 >A/******/index/2009/02/01                              2280 2274 2151 1701 1497 1410  982  838   

 30:135,  7,155,722,168,630, 89, 63   KF805633,A/Helsinki/716/2013,2013/02/16,Finland,H3N2 
 31:137,  7,153,722,171,630,108, 91   KF805641,A/Helsinki/798/2013,2013/02/20,Finland,H3N2 
 32:129,  9,142,721,174,629,110,106   KF805649,A/Helsinki/823/2013,2013/02/21,Finland,H3N2 
 33:154, 15,162,714,180,632,116,175   KF805657,A/Helsinki/824/2013,2013/02/21,Finland,H3N2 
 34:159, 67,168,717,178,632,130,189   KF805665,A/Helsinki/879/2013,2013/02/24,Finland,H3N2 
 35:123,  4,155,722,171,630, 69, 75   KF805673,A/Helsinki/897/2013,2013/02/26,Finland,H3N2 
 36:143,  6,151,719,172,628,106,113   KF805681,A/Helsinki/941/2013,2013/02/27,Finland,H3N2 
 37:154,  8,164,715,180,632,122,159   KF805689,A/Helsinki/942/2013,2013/02/27,Finland,H3N2 
 38:160, 69,164,713,180,633,132,188   KF805697,A/Helsinki/951/2013,2013/03/01,Finland,H3N2 
 39:156, 29,167,717,178,631,126,181   KF805705,A/Helsinki/991/2013,2013/03/02,Finland,H3N2
-------------------------------------------------------------


Submitted (05-NOV-2013) Institute for Molecular Medicine Finland
(FIMM), P.O. Box 20, Helsinki, Uusimaa FI-00014, Finland
Assembly Method :: Interactive Genome Viewer IGV v. 2.0
Sequencing Technology :: Illumina
nasopharyngeal swab"
/country="Finland: Helsinki"
/collection_date="26-Feb-2013"
/note="passage details: MDCK 4"

--------------------------------------------------------------

looking at segment 8 ... it's so different from any other known segment 8
best match in flu,segment 8,full length,outside Helsinki is Texas,H1N1,Dec.2012
with 56(!) differences, the ****** index has 63 differences, 1918 Spainflu has
120 differences. The differences are not concentrated in some region
as in recombination, but scattered through the whole 838 nucleotides
of the coding region of segment 8.

The best explanation that I can find is, that they have some systematic error
that produces incorrect mutations, some severe confusion/mixing maybe, with
other sequences from the same run.

makes the other segments also dubitious, Sydney/1997
----------------------------------------------

genbank classifies these 11 Finnish H3N2-segments as pH1N1=******:
(thus making it H3N2-H1N1 reassortments)
8 times segment 2, 2 times segment 8, 1 time segment 7

>KF805634,A/Helsinki/716/2013,2013/02/16,Finland,H3N2,Human,2
>KF805636,A/Helsinki/716/2013,2013/02/16,Finland,H3N2,Human,8
>KF805642,A/Helsinki/798/2013,2013/02/20,Finland,H3N2,Human,2
>KF805650,A/Helsinki/823/2013,2013/02/21,Finland,H3N2,Human,2
>KF805658,A/Helsinki/824/2013,2013/02/21,Finland,H3N2,Human,2
>KF805674,A/Helsinki/897/2013,2013/02/26,Finland,H3N2,Human,2
>KF805676,A/Helsinki/897/2013,2013/02/26,Finland,H3N2,Human,8
>KF805679,A/Helsinki/897/2013,2013/02/26,Finland,H3N2,Human,7
>KF805682,A/Helsinki/941/2013,2013/02/27,Finland,H3N2,Human,2
>KF805690,A/Helsinki/942/2013,2013/02/27,Finland,H3N2,Human,2
>KF805706,A/Helsinki/991/2013,2013/03/02,Finland,H3N2,Human,2