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H3N2 viruses mutate during vaccine production but new tech could fix it
April 29, 2019 By Kelly April Tyrrell
In late March 2019, the World Health Organization and a vaccine advisory committee of the Food and Drug Administration selected the final influenza strains to include in the vaccines produced for the next flu season. These include H1N1, influenza B, and H3N2 viruses.
The goal is to find the best match between the vaccine and the influenza strains most likely to be circulating in the environment, particularly because flu viruses frequently mutate and can differ across time and from region to region. One common problem, however, is that the viruses chosen for vaccines often mutate in the process of production, creating mismatches between seasonal flu viruses and the vaccine in any given flu season. This has been a particular problem with H3N2 viruses.
But a new technology developed by the University of Wisconsin??Madison?s Yoshihiro Kawaoka may make H3N2 vaccine development a bit easier. In Nature Microbiology today
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April 29, 2019 By Kelly April Tyrrell
In late March 2019, the World Health Organization and a vaccine advisory committee of the Food and Drug Administration selected the final influenza strains to include in the vaccines produced for the next flu season. These include H1N1, influenza B, and H3N2 viruses.
The goal is to find the best match between the vaccine and the influenza strains most likely to be circulating in the environment, particularly because flu viruses frequently mutate and can differ across time and from region to region. One common problem, however, is that the viruses chosen for vaccines often mutate in the process of production, creating mismatches between seasonal flu viruses and the vaccine in any given flu season. This has been a particular problem with H3N2 viruses.
But a new technology developed by the University of Wisconsin??Madison?s Yoshihiro Kawaoka may make H3N2 vaccine development a bit easier. In Nature Microbiology today
..
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