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In Australia, patients who were vaccinated against influenza during the current and previous season were less likely to develop severe illnesses requiring hospitalization compared with patients who were vaccinated during only a single season, according to recent study findings.
Previously, several studies predominantly conducted in North America and Europe have suggested that serial vaccination may attenuate vaccine effectiveness (VE), particularly against influenza A(H3N2) and B strains, which raises questions regarding optimal vaccination strategies, according to Allen C. Cheng, PhD, MPH, of the Infection Prevention and Healthcare Epidemiology Unit at Monash University?s School of Public Health and Preventative Medicine, and colleagues. However, the effects of serial vaccination on VE remain uncertain in the Southern Hemisphere.
Cheng and colleagues examined data from the Influenza Complications Alert Network, a surveillance program that monitors hospitalizations with laboratory-confirmed influenza in Australia, to determine whether VE was similar among patients who received a vaccine during two or more seasons and patients who received a vaccine during one season. The analysis included 3,821 patients aged 9 years or older who were hospitalized with influenza from 2010 to 2015 and 4,115 matched controls.
Previously, several studies predominantly conducted in North America and Europe have suggested that serial vaccination may attenuate vaccine effectiveness (VE), particularly against influenza A(H3N2) and B strains, which raises questions regarding optimal vaccination strategies, according to Allen C. Cheng, PhD, MPH, of the Infection Prevention and Healthcare Epidemiology Unit at Monash University?s School of Public Health and Preventative Medicine, and colleagues. However, the effects of serial vaccination on VE remain uncertain in the Southern Hemisphere.
Cheng and colleagues examined data from the Influenza Complications Alert Network, a surveillance program that monitors hospitalizations with laboratory-confirmed influenza in Australia, to determine whether VE was similar among patients who received a vaccine during two or more seasons and patients who received a vaccine during one season. The analysis included 3,821 patients aged 9 years or older who were hospitalized with influenza from 2010 to 2015 and 4,115 matched controls.
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