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St. Jude scientists produce vaccine that could fight bird flu

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  • St. Jude scientists produce vaccine that could fight bird flu

    A center that does primary research in cancer in the news again on the Bird Flu frontlines... maybe those researchers are willing to look outside the box?.... who knows but the research is promising.

    St. Jude scientists produce vaccine that could fight bird flu
    Memphis Business Journal - 11:16 AM CDT Tuesday


    Scientists at St. Jude Children's Research Hospital have hit the Holy Grail of flu vaccines, successfully protecting mice and ferrets with a commercial product expected to also protect humans against bird flu.

    Richard Webby, Ph.D., assistant member of Infectious Diseases at St. Jude, will present the findings Wednesday at the U.S. Public Health Service Professional Conference in Denver.

    A St. Jude scientist, Erich Hoffmann, developed a technique to reverse engineer viruses, breaking them down into eight pieces. From there it's a simple process to reassemble the virus but swap out some of the components, and create a perfect vaccine.

    That technology was central to developing the vaccine, by Vical Inc. (NASDAQ: VICL) of San Diego.

    Researchers used two versions of Vical's vaccine. One targets three distinct proteins, the other targets two of those proteins. By disrupting the proteins' ability to mutate, the virus is unable to morph into new versions. One reason avian flu is so vicious is that it can change constantly, dodging the immune system.

    Researchers tested the vaccines against the most virulent version of bird flu virus, which has killed people in Vietnam.

    By targeting the proteins common to different versions of the virus, the vaccines provide cross-protection.

    "Such cross-protection against bird and human influenza is considered by researchers to be the Holy Grail of flu vaccines," Webby said in a statement. "Even if the bird flu virus mutates so it becomes adapted to humans, this kind of cross protection will allow the immune system to track and attack such an emerging new variant without missing a beat."
    "Predictable is Preventable" by Safety Expert Dr. Gordon Graham.

  • #2
    Re: St. Jude scientists produce vaccine that could fight bird flu

    I think this may have been brought up in some form - do you have any info on testing or estimated production dates?
    .
    "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

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    • #3
      Re: St. Jude scientists produce vaccine that could fight bird flu

      "A St. Jude scientist, Erich Hoffmann, developed a technique to reverse engineer viruses, breaking them down into eight pieces. From there it's a simple process to reassemble the virus but swap out some of the components, and create a perfect vaccine."

      A simple process? Right. Does anyone else find it strange they discovered this "simple" process right before a possible pandemic? This will be a fun story to watch unfold. The outcome is predictable.

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      • #4
        Re: St. Jude scientists produce vaccine that could fight bird flu

        The actions of many people, when evolving research and technology is introduced, is predicatable and preventable through knowledge and education on the subject....
        "Predictable is Preventable" by Safety Expert Dr. Gordon Graham.

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        • #5
          Re: St. Jude scientists produce vaccine that could fight bird flu

          Originally posted by Roman
          .......find it strange they discovered this "simple" process right before a possible pandemic? ........
          I'd say they probably have increased motivation (like their families well being) .....backed by more $$$$

          The process has been used before and the theory has been discussed before.

          They are imitating the human cell-mediated immune system - the part that targets the conserved proteins.

          With the right incentives you can accomplish miracles.

          .
          "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

          Comment


          • #6
            Re: St. Jude scientists produce vaccine that could fight bird flu

            "With the right incentives you can accomplish miracles"
            or With the right incentives the public/governemnt will spend billions on a "simple" vaccine.
            This whole "St. Jude" situation doesn't feel right.

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            • #7
              Re: St. Jude scientists produce vaccine that could fight bird flu

              "The actions of many people, when evolving research and technology is introduced, is predicatable and preventable through knowledge and education on the subject...."

              Lobo, give it a rest. Your pretense is, once again, on the rise. You see the medical community as a knight in shining armor, with the single goal of saving man. I believe the situation is "evolving" and more complex. This view did not arise from a lack of "knowledge and education."

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              • #8
                Re: St. Jude scientists produce vaccine that could fight bird flu

                Roman,

                Great hypothesis...

                Please expand critically on your thoughts and research.
                "Predictable is Preventable" by Safety Expert Dr. Gordon Graham.

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                • #9
                  Re: St. Jude scientists produce vaccine that could fight bird flu

                  Here's some good info:

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                  • #10
                    Re: St. Jude scientists produce vaccine that could fight bird flu

                    Here is a very interesting story. Please read:

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                    • #11
                      Re: St. Jude scientists produce vaccine that could fight bird flu

                      St. Jude Study, apparently, may?<o:p></o:p>


                      Tamiflu may help prevent death of animals in bird flu

                      5/3/2006
                      (WROC-TV)

                      The antiviral drug Tamiflu apparently is able to prevent death in animals infected with the deadly bird flu virus.

                      A group of researchers from St. Jude Children's Research Hospital in Memphis announced the results of their study on ferrets at a two-day bird flu conference in Singapore run by "The Lancet" medical journal.

                      The group of ferrets given Tamiflu had the virus present only in their brains several hours after the treatment.

                      The ferrets who did not get the treatment, all died with their brains, lungs, intestines and spleens all infected with the virus.

                      The researchers say more study is needed.



                      And they making a vacine ????

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                      • #12
                        Re: St. Jude scientists produce vaccine that could fight bird flu

                        They knew this with the Thailand tigers and mice.

                        .
                        "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

                        Comment

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