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how to find the optimal vaccine

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  • how to find the optimal vaccine

    http://www.sciencedirect.com/science...fe5242fe4475fc

    Received 17 March 2003; accepted 10 August 2004. Available online 22 September 2004.
    ...We use a theory from statistical mechanics to quantify the non-monotonic immune response
    that results from antigenic drift in the epitopes of the hemagglutinin and neuraminidase proteins.
    The results explain the ineffectiveness of the 2003?2004 influenza vaccine in the United States
    and provide an accurate measure by which to optimize the effectiveness of future annual
    influenza vaccines.
    Keywords: Influenza vaccine; Original antigenic sin; Antigenic drift
    I'm interested in expert panflu damage estimates
    my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

  • #2
    Re: how to find the optimal vaccine

    Paper can be downloaded at:

    http://arxiv.org/abs/q-bio?papernum=0408016

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