Re: (almost) no recombination in flu-B
No it can't. G743A is silent and appeared on multiple genetic backgrounds.
Each of these backgrounds picked up 2-6 changes and one was G743A and they all happened at the same time. Random mutation / selection doesn't explain this, which is why I use it as an example. Most of the time the data is not quite this dramatic, but I use G743A to eliminate the error/selection argument (but as noted above, it is still cited).
The random muttaion / selection mantra also gets very old very fast.
Originally posted by Hanshilinzuo
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Each of these backgrounds picked up 2-6 changes and one was G743A and they all happened at the same time. Random mutation / selection doesn't explain this, which is why I use it as an example. Most of the time the data is not quite this dramatic, but I use G743A to eliminate the error/selection argument (but as noted above, it is still cited).
The random muttaion / selection mantra also gets very old very fast.
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