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Influenza: Random Thoughts and Comments

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  • #16
    Re: Influenza: Random Thoughts and Comments

    Emily,
    I did not see that staph vax news; that's great!

    This is from your Berkeley report, in case we ever want it for comparisons

    For example, because of wood availabilities, Finland, Sweden, and Canada burn more biomass fuel per capita than other countries and South Korea and Singapore burn less [2].
    On a personal level, I'm very allergic to smoke; too much will send me to the doctor. Unfortunately, I have a neighbor who burns everything he possibly can plus he has a wood stove. The wind blows it all in my direction. I'm not associated with air purifier companies in any way; but the one I have works well.
    The salvage of human life ought to be placed above barter and exchange ~ Louis Harris, 1918

    Comment


    • #17
      Re: Influenza: Random Thoughts and Comments

      I'm sorry to hear that you're impacted by bad air quality, mixin. You aren't alone. I was really sick for about 3 weeks over the holidays & it all started with an exposure to something that smelled really toxic while out driving. It smelled like someone was burning creosote treated wood. While recovering from that, we got some sort of upper respiratory illness and someone in the local neighborhood was generating HUGE amounts of smoke at night during this time, likely from banking the stove at night, or burning unseasoned wood. (Couldn't figure out who it even was.) So I kept going downhill. I was really disappointed that the natural remedies I started since 2009 and measures I've taken to reduce smoke exposure didn't prevent this illness. The smoke was so intense this year that it overwhelmed my HEPA's and heavy-duty charcoal/potassium permanganate filter, (all freshly replace this year, too).
      Even if someone doesn't have a classical allergy to smoke, they can be killed or sickened by reactions to it. I think overexposure causes immune dysregulation, and I've seen research that supports that. What is happening is more of an autoimmune reaction, and it is hard to treat.

      I'm not sure of what the mechanism is with the problems that children are having here in the Puget Sound region, but it is really sad:
      http://www.npr.org/templates/story/s...ryId=143842355
      Where There's Smoke, There's Sickness: Wood Smoke now a major Northwest air polluter

      by Robert McClure, InvestigateWest and Katie Campbell, EarthFix/KCTS 9
      December 16, 201112:26 PM
      ...
      David Ricker is a lung doctor who treats children at the Mary Bridge Children's Hospital in Tacoma, where the most common diagnosis of kids admitted is bronchialitis, constriction of the small lung airways that leaves children wheezing and in need of oxygen in the hospital for several days. Ricker says that his caseload goes up in the fall and winter, and he's sure wood smoke contributes.

      On a recent day Ricker treated a two-year-old boy who had been brought into the emergency room coughing and wheezing so hard that the skin at the bottom of his throat and on his ribcage was sucked in on each breath. A tube attached to a breathing machine had to be put down his windpipe. The same boy had been to Mary Bridge in the same condition multiple times.
      We can save the lives of children sickened by smoke exposure here, but the suffering is hidden from public view. In a refugee camp, however, nothing can be hidden. Someone from Syria posted a very disturbing photo of a little child killed by wood smoke in recently:

      https://twitter.com/RevolutionSyria/...208192/photo/1
      Suffered cold, hunger & bombing; then suffocated by the smoke of wood-burning stove
      _____________________________________________

      Ask Congress to Investigate COVID Origins and Government Response to Pandemic H.R. 834

      i love myself. the quietest. simplest. most powerful. revolution ever. ---- nayyirah waheed

      "...there’s an obvious contest that’s happening between different sectors of the colonial ruling class in this country. And they would, if they could, lump us into their beef, their struggle." ---- Omali Yeshitela, African People’s Socialist Party

      (My posts are not intended as advice or professional assessments of any kind.)
      Never forget Excalibur.

      Comment


      • #18
        Re: Influenza: Random Thoughts and Comments

        Gs and I have been having a rather long, rambling conversation about the pneumonia vaccine; I was wondering if that is giving the protection against death for those under the age of 24 and 65+. I've done quite a bit of searching and cannot find the number of years the childhood vax is good for. Since it's recommended that adults with underlying health conditions get vaxed, I'm assuming the protection is limited to X number of years.

        We wondered if H1N1 opens the door for Pneumococcal infection (refers to an infection caused by Streptococcus pneumoniae), which is mostly covered by the pneumonia vax; and H3 somehow opens the door to those which aren't covered.

        Gs also questions why we don't have pneumonia vax for those bacterial strains which are becoming antibiotic resistant. I've read that as one strain of bacteria is covered by the vax, others take its place.

        I was curious about the causes of pneumonia deaths so gs went through the records and gave me this for 2010. I re-formatted it a bit; if anyone wants to see the codes, etc, I can post them. I also question what "unspecified" means; did they not test to see or did they just omit that info from the death certificate? The number of unspecified cases is quite large.

        Code:
        numbers of deaths, causes:
          227: Influenza due to identified avian influenza virus
           30: Influenza with pneumonia, influenza virus identified
           27: Influenza with other respiratory manifestations, influenza virus identified
            3: Influenza with other manifestations, influenza virus identified
          112: Influenza with pneumonia, virus not identified
           92: Influenza with other respiratory manifestations, virus not identified
           10: Influenza with other manifestations, virus not identified
           14: Adenoviral pneumonia
           
           18: J121 (I'm not sure what this little group is)
            3: J122
            3: J128
          133: J129
        
        43864: Pneumonia, [B]unspecified[/B]
         1775: Lobar pneumonia, unspecified
          955: Bronchopneumonia, unspecified
        
          625: Pneumonia due to staphylococcus
          
          277: Pneumonia due to Streptococcus pneumoniae
            2: Pneumonia due to streptococcus, group B 
          189: Pneumonia due to other streptococci
         
           31: Pneumonia due to Haemophilus influenzae 
           88: Pneumonia due to Klebsiella pneumoniae
          231: Pneumonia due to Pseudomonas
        
           25: Pneumonia due to Escherichia coli
           24: Pneumonia due to other aerobic Gram-negative bacteria
           24: Pneumonia due to Mycoplasma pneumoniae
           39: Other bacterial pneumonia
         1264: Bacterial pneumonia, unspecified
        
           64: Hypostatic pneumonia, unspecified
           12: Other pneumonia, organism unspecified
        In the United States, the most common viral causes of pneumonia are influenza and respiratory syncytial virus (RSV), and the most common bacterial cause is Streptococcus pneumoniae (pneumococcus). In children younger than 1 year of age, RSV is the most common cause of pneumonia.
        http://www.cdc.gov/features/pneumonia/

        Prevnar 13? is a vaccine approved for children 6 weeks through 17 years of age for the prevention of invasive disease caused by 13 Streptococcus pneumoniae strains (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F), and for children 6 weeks through 5 years for the prevention of otitis media caused by 7 of the 13 strains (4, 6B, 9V, 14, 18C, 19F, and 23F)
        http://www.prevnar13.com/
        The salvage of human life ought to be placed above barter and exchange ~ Louis Harris, 1918

        Comment


        • #19
          Re: Influenza: Random Thoughts and Comments

          I've seen several reports of people being ill with pneumonia prior to getting the flu & the article below indicates there is a synergy between bacteria and the flu virus.

          Secondary Bacterial Pneumonia
          Bacterial pneumonia complicating viral influenza was reported
          during the pandemic of 1918 and multiple subsequent
          epidemic and inter-epidemic periods.22,23 Typical viral
          influenza infection is followed by near resolution of
          symptoms, subsequently complicated 4 to 14 days later by
          a recurrence of fever, dyspnea, productive cough, and pulmonary
          consolidation.28 The most common pathogens are
          Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus
          influenzae, and occasionally other gram-negative
          bacilli.
          29
          S. aureus pneumonia following influenza was first described
          during the 1918 pandemic.
          Striking features included
          a fulminant course, unusual cyanosis (?cherry-red
          indigo-blue?), lack of consolidation on pulmonary examination,
          dirty salmon-pink purulent sputum, leucopenia, multiple
          micro-abscesses on autopsy, and a near-universal fatality.
          30 Subsequent reports confirmed an increased incidence
          of S. aureus pneumonia during the epidemic of 1968 to
          1969
          .29 Staphylococcal toxic shock syndrome arising from
          the respiratory tract during influenza infection also has been
          described.31 During the 2003 to 2004 and 2006 to 2007
          influenza seasons, cases of severe community-acquired
          pneumonia due to methicillin-resistant S. aureus (MRSA)
          were reported with 33% mortality.32,33
          The mechanisms by which bacteria act synergistically
          with influenza virus include increased binding and invasion
          of bacteria, increased viral replication, and modification of
          the host inflammatory response. The interactions between
          influenza virus and bacteria have most thoroughly been
          established with streptococcus pneumoniae. As the viral
          neuraminidase cleaves sialic acid to release new viral particles
          from host cells, damage to the epithelial layer of the
          airways occurs, exposing binding sites necessary for adherence
          of the pneumococcus.34
          Pulmonary Complications with Unusual
          Pathogens

          Multiple reports describe secondary pneumonia caused by
          less common microorganisms. These include Aspergillus
          sp., Chlamydia pneumoniae, B-hemolytic streptococci, and
          Legionella pneumophila.35-38 Six cases of invasive aspergillosis
          have been reported, all in immunocompetent persons,
          with 5 deaths.

          Noninfectious mimics of infection that may be incited by
          influenza include..
          The American Journal of Medicine (2008) 121, 258-264
          _____________________________________________

          Ask Congress to Investigate COVID Origins and Government Response to Pandemic H.R. 834

          i love myself. the quietest. simplest. most powerful. revolution ever. ---- nayyirah waheed

          "...there’s an obvious contest that’s happening between different sectors of the colonial ruling class in this country. And they would, if they could, lump us into their beef, their struggle." ---- Omali Yeshitela, African People’s Socialist Party

          (My posts are not intended as advice or professional assessments of any kind.)
          Never forget Excalibur.

          Comment


          • #20
            Re: Influenza: Random Thoughts and Comments

            comparing strep and staph pneumonia deaths gives nothing
            remarkable at first sight

            http://www.icd10data.com/Convert/482.39

            http://www.icd10data.com/ICD10CM/Cod...J18/J15-/J15.2
            http://www.icd10data.com/ICD10CM/Cod...J18/J15-/J15.4
            http://www.icd10data.com/ICD10CM/Cod...9-J18/J13-/J13


            ICD7:1959-1967 bacteria not distinguished
            ICD8:1968-1978
            ICD9:1979-1998
            ICD10:1999-

            specifications changed in 1979 and 1999, so changes in those years are
            probably due to changes in reporting guidelines


            Code:
            reported US-pneumonia-deaths 1999-2010
            
                staph strep  ratio
            ---------------------
            Jan  1407  1475  1.0483 
            Feb  1549  1155   .7455 
            Mar  1505  1105   .7342 
            Apr  1200   831   .6925 
            May   989   682   .6895 
            Jun   897   495   .5518 
            Jul   887   337   .3799 
            Aug   796   255   .3203 
            Sep   770   359   .4657 
            Oct   872   476   .5458 
            Nov   921   691   .7508 
            Dec  1176  1041   .8852
            Code:
            by 20 age5groups
            
             J13 J152 J154
            ----------------
              71   75  157 
              12   14   24 
               *   39   17 
              16   30   17 
              25   54   17 
              41   56   30 
              77   74   66 
             158  128   99 
             272  196  159 
             325  277  223 
             375  417  227 
             452  518  227 
             360  636  243 
             349  843  199 
             395 1348  235 
             540 1878  311 
             612 2315  359 
             657 2171  382 
             413 1173  246 
             175  454  102
            streptococci and staphylococci also cause deaths from other diseases,
            tabulated elsewhere. Septicaemia,meningitis,pharyngitis,tonsillitis
            bronchitis,scalded skin,arthritis,


            ICD9 had a large group 481 with 52635 deaths from "pneumococcal pneumonia"

            ICD-9-CM 481 converts approximately to:
            ?2014 ICD-10-CM J13 Pneumonia due to Streptococcus pneumoniae
            or:
            ?2014 ICD-10-CM J18.1 Lobar pneumonia, unspecified organism

            Code:
            ICD9 , 1979-1998
                  480   Viral pneumonia
              134 480.0 Pneumonia due to adenovirus
              499 480.1 Pneumonia due to respiratory syncytial virus
               22 480.2 Pneumonia due to parainfluenza virus
               67 480.8 Pneumonia due to other virus not elsewhere classified
            11758 480.9 Viral pneumonia, unspecified
            52635 481   Pneumococcal pneumonia
                  482   Other bacterial pneumonia
             5746 482.0 Pneumonia due to Klebsiella pneumoniae
             9191 482.1 Pneumonia due to Pseudomonas
             1690 482.2 Pneumonia due to Haemophilus influenzae [H. influenzae]
             5571 482.3 Pneumonia due to Streptococcus
                  482.30 Streptococcus, unspecified
                  482.31 Group A
                  482.32 Group B
                  482.39 Other Streptococcus
            13978 482.4 Pneumonia due to Staphylococcus
             4490 482.8 Pneumonia due to other specified bacteria
                  482.81 Anaerobes
                  482.82 Escherichia coli [E. coli]
                  482.83 Other gram-negative bacteria
                  482.89 Other specified bacteria
            20295 482.9 Bacterial pneumonia unspecified
             2391 483   Pneumonia due to other specified organism
                  483.0 Mycoplasma pneumoniae
                  483.8 Other specified organism
                  484   Pneumonia in infectious diseases classified elsewhere
                  484.0 Pneumonia in measles
                  484.1 Pneumonia in cytomegalic inclusion disease
                  484.2 Pneumonia in ornithosis
                  484.3 Pneumonia in whooping cough
                  484.4 Pneumonia in tularaemia
                  484.5 Pneumonia in anthrax
                  484.6 Pneumonia in aspergillosis
                  484.7 Pneumonia in other systemic mycoses
                  484.8 Pneumonia in other infectious diseases classified elsewhere
            148575 485   Bronchopneumonia, organism unspecified
            1116365 486   Pneumonia, organism unspecified
                  487   Influenza
            12931 487.0 With pneumonia
            14424 487.1 With other respiratory manifestations
              636 487.8 With other manifestations
            Code:
            ICD10, 1999-
                  J12   Viral pneumonia, not elsewhere classified
              132 J12.0 Adenoviral pneumonia
              263 J12.1 Respiratory syncytial virus pneumonia
               29 J12.2 Parainfluenza virus pneumonia
               24 J12.8 Other viral pneumonia
             2894 J12.9 Viral pneumonia, unspecified
             5328 J13   Pneumonia due to Streptococcus pneumoniae
              490 J14   Pneumonia due to Haemophilus influenzae
                  J15   Bacterial pneumonia, not elsewhere classified
             1459 J15.0 Pneumonia due to Klebsiella pneumoniae
             3602 J15.1 Pneumonia due to Pseudomonas
            12696 J15.2 Pneumonia due to staphylococcus
               45 J15.3 Pneumonia due to streptococcus, group B
             3340 J15.4 Pneumonia due to other streptococci
              305 J15.5 Pneumonia due to Escherichia coli
              368 J15.6 Pneumonia due to other aerobic Gram-negative bacteria
              322 J15.7 Pneumonia due to Mycoplasma pneumoniae
              443 J15.8 Other bacterial pneumonia
            19605 J15.9 Bacterial pneumonia, unspecified
                  J16   Pneumonia due to other infectious organisms, not elsewhere classified
               24 J16.0 Chlamydial pneumonia
               39 J16.8 Pneumonia due to other specified infectious organisms
                  J17   Pneumonia in diseases classified elsewhere
                  J17.0 Pneumonia in bacterial diseases classified elsewhere
                  J17.1 Pneumonia in viral diseases classified elsewhere
                  J17.2 Pneumonia in mycoses
                  J17.3 Pneumonia in parasitic diseases
                  J17.8 Pneumonia in other diseases classified elsewhere
                  J18   Pneumonia, organism unspecified
            17197 J18.0 Bronchopneumonia, unspecified
            19242 J18.1 Lobar pneumonia, unspecified
              688 J18.2 Hypostatic pneumonia, unspecified
              428 J18.8 Other pneumonia, organism unspecified
            609982 J18.9 Pneumonia, unspecified
            Attached Files
            I'm interested in expert panflu damage estimates
            my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

            Comment


            • #21
              Re: Influenza: Random Thoughts and Comments

              I'm putting your chart here. What happened in 2000 that made Strep increase?

              Strep and Staph Comparison.jpg

              This is from your CDC link. Notice that same age group that we've discussed (5-24) has the lowest mortality. Look at how it increases beginning with the 25-34 group. Do we have that same link for staph so we can compare ages?

              Strep Pneumonia CDC Code.jpg
              The salvage of human life ought to be placed above barter and exchange ~ Louis Harris, 1918

              Comment


              • #22
                Re: Influenza: Random Thoughts and Comments

                Emily, thanks for your link. It has a lot of good info.

                I always wondered how the flu opened the door for bacteria; this from your quote explains it.

                The interactions between influenza virus and bacteria have most thoroughly been established with streptococcus pneumoniae. As the viral neuraminidase cleaves sialic acid to release new viral particles from host cells, damage to the epithelial layer of the airways occurs, exposing binding sites necessary for adherence of the pneumococcus.
                The salvage of human life ought to be placed above barter and exchange ~ Louis Harris, 1918

                Comment


                • #23
                  Re: Influenza: Random Thoughts and Comments

                  update



                  (sorry, I had to correct the earlier version from about 1 hour ago)



                  see the (positive) effect of Christmas holiday in the 5-14 agegroup
                  Attached Files
                  I'm interested in expert panflu damage estimates
                  my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

                  Comment


                  • #24
                    Re: Influenza: Random Thoughts and Comments

                    Air Pollution and Health - Google Books
                    Holgate

                    google links are awful , use search engine
                    Attached Files
                    I'm interested in expert panflu damage estimates
                    my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

                    Comment


                    • #25
                      Re: Influenza: Random Thoughts and Comments

                      while examining deaths from cold-spells
                      I found the London fogs from 1880,1873,1863

                      http://archive.spectator.co.uk/artic...g-is-well-illu
                      Attached Files
                      I'm interested in expert panflu damage estimates
                      my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

                      Comment

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