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Synthetic carbohydrates against autoimmune diseases

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  • Synthetic carbohydrates against autoimmune diseases

    Researchers are developing an innovative approach for the treatment of a rare autoimmune disease of the peripheral nervous system, using a type of molecular sponge consisting of carbohydrates to remove pathogenic antibodies from the bloodstream. Developed to treat anti-MAG neuropathy, the approach also has potential applications for the treatment of other autoimmune diseases. Scientists from the University of Basel and University Hospital Basel have reported their findings in the scientific journal PNAS.

    Synthetic carbohydrates against autoimmune diseases

    April 17, 2017

    Researchers are developing an innovative approach for the treatment of a rare autoimmune disease of the peripheral nervous system, using a type of molecular sponge consisting of carbohydrates to remove pathogenic antibodies from the bloodstream. Developed to treat anti-MAG neuropathy, the approach also has potential applications for the treatment of other autoimmune diseases. Scientists from the University of Basel and University Hospital Basel have reported their findings in the scientific journal PNAS...

    More information: Ruben Herrendorff el al., "Selective in vivo removal of pathogenic anti-MAG autoantibodies, an antigen-specific treatment option for anti-MAG neuropathy," PNAS (2017). www.pnas.org/cgi/doi/10.1073/pnas.1619386114
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