Announcement

**AlaskaDenise** · December 15, 2009, 06:51 AM

Re: interesting recent avian viruses

Why are they interesting? or significant?

.

**gsgs** · February 8, 2010, 04:06 AM

Re: interesting recent avian viruses

A/chicken/Beijing/1/1994(H9N2)

several strains (~5 ?) of H9N2 are circulating in Asian poultry
presumably from different introductions from wild birds.
From 2002 on there were several reassortments with H5N1 and
H5N1 acquired segments from H9N2 and H6N1, although the
"genotype Z" dominant since 2003 presumably got it from
wild birds with H9N2, not poultry. (Not so HK 1997)

When and how these introductions happened (and how to prevent them)
is an intereting question.

The Beijing chicken is the earliest record so far from one of the strains.

It already has 19,15,18,-,15,-,19,17 amino-acid differences from the index.
So I assume the introduction happened in the 80s or 70s or even
earlier.

To compare:
the related A/chicken/Yokohama/aq45/2002(H9N2) has 22,21,19,-,15,-,14,21 differences
(apparantly another segment 7 through reassortment)

genotype Z/2002(H5N1) has 3,6,7,-,5,-,12,11 differences
the descendent A/bar-headed goose/Mongolia/X53/2009(H5N1) has 11,7,6,-,7,-,13,23 differences
A/Ck/Egypt/0891/2008(H5N1) has 15,13,15,-,11,-,15,20 differences

10 differences in 8 years in segments 1,2,3,5 in chicken
11 differences in 7 years in segments 1,2,3,5 in wild birds
26 differences in 6 years in segments 1,2,3,5 in chicken

**gsgs** · April 9, 2010, 07:08 AM

Re: interesting recent avian viruses

38 new genomes from Netherlands,Sweden !

not yet available through the main genbank search page, maybe tomorrow...

A/common teal/Netherlands/10/2000(H1N1)
A/common teal/Netherlands/9/2000(H11N9)
A/common teal/Sweden/1/2003(H3N3)
A/greylag goose/Netherlands/4/1999(H6N1)
A/mallard/Netherlands/1/1999(H4N6)
A/mallard/Netherlands/1/2002(H4N6)
A/mallard/Netherlands/10/1999(H1N8)
A/mallard/Netherlands/12/2001(H4N2)
A/mallard/Netherlands/15/1999(H11N9)
A/mallard/Netherlands/2/1999(H3N5)
A/mallard/Netherlands/5/2001(H3N6)
A/mallard/Sweden/110/2002(H11N7)
A/mallard/Sweden/24/2002(H8N4)
A/mallard/Sweden/25/2002(H11N3)
A/mallard/Sweden/3/2002(H1N2)
A/mallard/Sweden/4/2002(H10N2)
A/mallard/Sweden/41/2002(H10N6)
A/mallard/Sweden/45/2002(H11N8)
A/mallard/Sweden/46/2002(H4N3)
A/mallard/Sweden/48/2002(H11N9)
A/mallard/Sweden/50/2002(H3N8)
A/mallard/Sweden/52/2003(H6N2)
A/mallard/Sweden/55/2002(H11N2)
A/mallard/Sweden/57/2003(H1N1)
A/mallard/Sweden/58/2003(H11N1)
A/mallard/Sweden/6/2002(H2N3)
A/mallard/Sweden/62/2003(H4N6)
A/mallard/Sweden/65/2002(H10N9)
A/mallard/Sweden/7/2003(H10N8)
A/mallard/Sweden/8/2003(H8N4)
A/mallard/Sweden/81/2002(H6N1)
A/mallard/Sweden/86/2003(H12N5)
A/mallard/Sweden/88/2002(H2N1)
A/mallard/Sweden/98/2002(H1N6)
A/northern pintail/Sweden/1/2003(H2N3)
A/northern shoveler/Netherlands/18/1999(H11N9)
A/whitefronted goose/Netherlands/1/1999(H6N1)
A/whitefronted goose/Netherlands/2/1999(H6N2)

**gsgs** · April 10, 2010, 03:22 AM

Re: interesting recent avian viruses

now 110 genomes from Netherlands and Sweden are availabe at genbank.

These are mainly mallards from 1999-2007.

American mallards (plus pintails,shovelers,turnstones) are also
available (1975-2008) give a similar result, maybe I can post it later.
Unfortunately there are only few examples from other continents

**gsgs** · May 11, 2010, 10:13 AM

Re: interesting recent avian viruses

An avian influenza A(H11N1) virus from a wild aquatic bird revealing a unique Eurasian-American genetic reassortment - PubMed

http://www.ncbi.nlm.nih.gov/pubmed/20440548

Influenza surveillance in different wild bird populations is critical for understanding the persistence, transmission and evolution of these viruses. Avian influenza (AI) surveillance was undertaken in wild migratory and resident birds during the period 2007-2008, in view of the outbreaks of highly …

LP H11N1 from India.
HA like A/shorebird/Delaware/236/2003(H11N9)
NA like A/duck/Mongolia/540/2001(H1N1)
other six genes Eurasian

**gsgs** · June 22, 2010, 07:35 AM

Re: interesting recent avian viruses

new genomes with protein differences to the bird-index:
A/mallard/NL/3/1999/10/09(H5N2) 1,1,2,-,8,-,5,*16
A/mallard/NL/5/1999/10/18(H2N9) 1,0,4,-,0,-,5,5

**gsgs** · July 29, 2010, 03:30 PM

Re: interesting recent avian viruses

rosy billed pochard from Argentina

apparantly South American avian flu evolves separately in segments
1,3,5 at least since >100 years

the equine flu H3N8 since 1983 is closest to
South American flu in segments 3,5

~20 avian genomes from South America and Africa would be useful.
And of course anything from before 1960

**gsgs** · August 27, 2010, 10:51 AM

Re: interesting recent avian viruses

pig with H11N6 !

CY073449 Swine 1 H11N6 South Korea 2001 2341 Influenza A virus (A/swine/KU/2/2001(H11N6)) yes

**gsgs** · September 5, 2010, 08:15 AM

Re: interesting recent avian viruses

flu from surface water

Influenza A virus (A/surface water/Minnesota/NW1-T/2006(H4N6)) segment - Nucleotide - NCBI

http://www.ncbi.nlm.nih.gov/nuccore/306022255?report=genbank

A/surface water/Minnesota/NW1-T/2006(H4N6)
TITLE Direct Submission
JOURNAL Submitted (03-SEP-2010) Department of Veterinary Population
Medicine, University of Minnesota, 1354 Eckles Avenue, Saint Paul,
MN 55108, USA

Influenza A virus (A/surface water/Minnesota/W07-2241/2007(H3N8)) poly - Nucleotide - NCBI

http://www.ncbi.nlm.nih.gov/nuccore/306022281?report=genbank

A/surface water/Minnesota/W07-2241/2007(H3N8)
Yang,M., Wang,P., Enomoto,S., Ramakrishnan,M.A., Lebarbenchon,C.,
Stallknecht,D.E. and Sreevatsan,S.

------------------------------------------------------------------------------
0 0 2280 2363 >A/surface water/Minnesota/NW1-T/2006(H4N6)
114 26 2280 1963 >A/blue-winged teal/Manitoba/13436/05(H3N8),2005,8,4,0
135 31 2280 1827 >A/mallard/Ohio/1851/05(H11N1),2005,3,4,0
135 31 2280 1846 >A/blue-winged teal/Ohio/1387/05(H6N2),2005,8,4,0
135 31 2280 1976 >A/snow Gs/Maryland/410/05(H6N1),2005,15,4,0
144 33 2280 1977 >A/snow Gs/Maryland/353/05(H6N1),2005,15,4,0
149 34 2280 1978 >A/snow Gs/Maryland/364/05(H6N1),2005,15,4,0
171 39 2280 1584 >A/mallard/Minnesota/249/00(H11N9),2000,3,4,0
175 40 2280 1586 >A/mallard/Minnesota/31/00(H2N9),2000,3,4,0
175 40 2280 2075 >A/blue-winged teal/Minnesota/Sg-00229/06(H4N6),2006,8,4,0

0 0 2274 2675 >A/surface water/Minnesota/NW1-T/2006(H4N6)
285 65 2274 1614 >A/pintail/ALB/275/96(H4N6)08,1996,6,4,0
330 75 2267 1020 >A/guillemot/Sweden/3/00(H6N2),2000,0,3,0
386 88 2274 1748 >A/mallard/MN/42/00(H11N9),2000,3,4,0

0 0 2151 2948 >A/surface water/Minnesota/NW1-T/2006(H4N6)
93 20 2135 2618 >A/mallard Dk/Minnesota/Sg-00100/07(H3N3)09/14, 2007 , 3 , 4 , 0
102 22 2151 2781 >A/mallard/Minnesota/Sg-00627/08(H1N1)07/29, 2008 , 3 , 0 , 0
102 22 2151 2782 >A/mallard/Minnesota/Sg-00628/08(H1N1)07/29, 2008 , 3 , 0 , 0
106 23 2151 2805 >A/N.shoveler/Minnesota/Sg-00651/08(H1N1)07/31, 2008 , 11 , 0 , 0
106 23 2151 2809 >A/N.shoveler/Minnesota/Sg-00655/08(H1N1)07/31, 2008 , 11 , 0 , 0

0 0 1497 2595 >A/surface water/Minnesota/NW1-T/2006(H4N6)
100 15 1497 2463 >A/mallard/Interior Alaska/2/07(H4N6)09/10, 2007 , 3 , 4 , 0
100 15 1497 2467 >A/mallard/Interior Alaska/7MP1050R1/07(H4N6)09/10, 2007 , 3 , 4 , 0
100 15 1497 2481 >A/American widgeon/CA/HKWF42/07(H6N1)10/21, 2007 , 16 , 4 , 0
106 16 1497 2445 >A/mallard/Interior Alaska/1/07(H4N5)09/03, 2007 , 3 , 4 , 0
106 16 1497 2471 >A/mallard/Interior Alaska/7MP1718/07(H4N5)09/16, 2007 , 3 , 4 , 0
113 17 1497 2444 >A/N.shoveler/Interior Alaska/1/07(H4N6)09/01, 2007 , 11 , 4 , 0
113 17 1497 2526 >A/green winged teal/CA/AKS1370/08(H7N3)01/27, 2008 , 8 , 4 , 0
126 19 1497 2396 >A/mallard/Quebec/11063/06(H2N3)08/19, 2006 , 3 , 4 , 0

0 0 759 2724 >A/surface water/Minnesota/NW1-T/2006(H4N6)
26 2 759 2253 >A/mallard/Ohio/363/03(H2N1),2003,3,4,0
26 2 759 2304 >A/mallard/Ohio/793/04(H11N2),2004,3,4,0
26 2 759 2493 >A/N.pintail/Illinois/464067-4/06(H5N9),2006,6,4,0
26 2 759 2503 >A/Muscovy Dk/NY/62095-1/06(H5N2)05/15,2006,10,4,0
26 2 759 2534 >A/mallard/Quebec/11247/06(H3N2)08/24,2006,3,4,0
39 3 759 2319 >A/american black Dk/Ohio/1823/05(H11N9),2005,10,4,0
39 3 759 2463 >A/mallard/Maryland/182/06(H5N2),2006,3,4,0
39 3 759 2527 >A/mallard/Quebec/11111/06(H11N9)08/20,2006,3,4,1
39 3 759 2533 >A/American black Dk/Quebec/11235/06(H3N2)08/24,2006,10,4,0
39 3 759 2605 >A/American widgeon/CA/HKWF41/07(H6N1)10/21,2007,16,4,1
39 3 759 2615 >A/American widgeon/CA/HKWF296/07(H6N1)10/31,2007,16,4,1
52 4 759 2235 >A/mallard/Maryland/750/02(H4N6)08/27,2002,3,4,0

0 0 838 3259 >A/surface water/Minnesota/NW1-T/2006(H4N6)
35 3 838 3064 >A/mallard/Quebec/11063/06(H2N3)08/19,2006,3,4,0
35 3 838 3077 >A/mallard/Quebec/11281/06(H2N3)08/25,2006,3,4,0
59 5 838 2841 >A/pintail/Alberta/49/03(H12N5)07/25,2003,6,4,0

-------------------------------------------------------------------------

0 0 2280 2364 >A/surface water/Minnesota/W07-2241/2007(H3N8)
175 40 2280 1574 >A/mallard/MN/109/00(H11N9),2000,3,4,0
179 41 2280 1579 >A/mallard/MN/479/00(H5N3),2000,3,4,0
188 43 2280 2185 >A/N.shoveler/CA/HKWF1026/07(H7N3),2007,11,4,0
206 47 2280 1673 >A/mallard/MD/403/02(H1N1),2002,3,4,0
228 52 2280 1580 >A/mallard/MN/113/00(H5N2),2000,3,4,0
228 52 2280 1940 >A/mallard/Alberta/11527/05(H3N8),2005,3,4,0
241 55 2280 1944 >A/pintail/Alaska/53/05(H3N6),2005,6,4,0

0 0 2274 2676 >A/surface water/Minnesota/W07-2241/2007(H3N8)
162 37 2274 2387 >A/N.pintail/CA/HKWF151/07(H6N1)10/24,2007,6,4,0
171 39 2274 2383 >A/American widgeon/CA/HKWF41/07(H6N1)10/21,2007,16,4,0
171 39 2274 2393 >A/American widgeon/CA/HKWF296/07(H6N1)10/31,2007,16,4,0

0 0 2151 2949 >A/surface water/Minnesota/W07-2241/2007(H3N8)
60 13 2142 2560 >A/blue-winged teal/Minnesota/Sg-00043/07(H4N6)08/03, 2007 , 8 , 4 , 0
60 13 2151 2540 >A/mallard/Minnesota/Sg-00230/06(H7N3)09/30, 2006 , 3 , 4 , 0
61 13 2130 2565 >A/mallard Dk/Minnesota/Sg-00053/07(H4N6)08/03, 2007 , 3 , 4 , 0
61 13 2131 2559 >A/blue-winged teal/Minnesota/Sg-00030/07(H4N6)08/03, 2007 , 8 , 4 , 0

0 0 1497 2596 >A/surface water/Minnesota/W07-2241/2007(H3N8)
33 5 1497 2440 >A/mallard/Interior Alaska/7MP0372/07(H4N6)08/17, 2007 , 3 , 4 , 0
40 6 1497 2431 >A/N.pintail/Interior Alaska/1/07(H4N6)08/08, 2007 , 6 , 4 , 0
40 6 1497 2436 >A/N.pintail/Alaska/7MP1393/07(H4N6)08/14, 2007 , 6 , 4 , 0
73 11 1497 2502 >A/American green-winged teal/CA/HKWF609/07(H5N2)11/10, 2007 , 8 , 4 , 0
100 15 1497 2479 >A/American widgeon/CA/HKWF371/07(H6N5)10/07, 2007 , 16 , 4 , 0
113 17 1497 2387 >A/shorebird/Delaware/249/06(H9N2)05/22, 2006 , 12 , 4 , 0
120 18 1497 2330 >A/snow Gs/Maryland/364/05(H6N1)12/13, 2005 , 15 , 4 , 0
120 18 1497 2500 >A/American widgeon/CA/HKWF541/07(H6N5)11/07, 2007 , 16 , 4 , 0
126 19 1497 1889 >A/blue-winged teal/Ohio/31/99(H3N2)10/16, 1999 , 8 , 4 , 0
146 22 1497 1867 >A/mallard/MN/160/99(H4N6), 1999 , 3 , 4 , 0
153 23 1497 1830 >A/mallard/Minnesota/114/98(H4N8), 1998 , 3 , 4 , 0

0 0 759 2725 >A/surface water/Minnesota/W07-2241/2007(H3N8)
52 4 759 2135 >A/mallard/Alberta/156/01(H3N8)08/06,2001,3,4,0
65 5 759 2003 >A/mallard/Alberta/125/99(H11N6)08/04,1999,3,4,0
92 7 759 1897 >A/mallard/MN/7/98(H11N2),1998,3,4,0
92 7 759 1928 >A/mallard/Minnesota/153/98(H9N2),1998,3,4,0
92 7 759 2274 >A/blue-winged teal/Alberta/293/03(H4N6)08/13,2003,8,4,0
92 7 759 2577 >A/N.shoveler/Interior Alaska/4/07(H3N8)09/05,2007,11,4,0
105 8 759 1841 >A/mallard/ALB/206/96(H6N8)08,1996,3,4,0
105 8 759 2271 >A/mallard/Alberta/209/03(H10N7)08/07,2003,3,4,0
105 8 759 2421 >A/mallard/Alberta/11527/05(H3N8)08/03,2005,3,4,0
105 8 759 2726 >A/bird/Alaska/Index/2006(H3N8)

0 0 838 3260 >A/surface water/Minnesota/W07-2241/2007(H3N8)
59 5 838 2980 >A/N.pintail/Alberta/11701/05(H3N8)08/05,2005,6,4,0
59 5 838 3114 >A/N.shoveler/Interior Alaska/1/07(H4N6)09/01,2007,11,4,0
71 6 838 3128 >A/mallard/Interior Alaska/4/07(H4N6)09/07,2007,3,4,0
83 7 838 3157 >A/N.pintail/CA/HKWF151/07(H6N1)10/24,2007,6,4,0

differences from the bird-index:

A/surface water/Minnesota/W07-2241/2007(H3N8)
6,5,13,6,2,9,1,3

>A/surface water/Minnesota/NW1-T/2006(H4N6)
3,2,5,-,2,-,2,2

paper:

Page not available - PMC

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197669/?tool=pubmed

**mixin** · September 5, 2010, 08:31 AM

Re: interesting recent avian viruses

They found H4N6 in a wild raccoon last year

We surveyed the wildlife inhabiting a poultry farm with recent H3N6 and H4N6 avian influenza virus exposure in Pennsylvania, U.S.A. One raccoon (Procyon lotor) tested positive for H4N6 antibodies. This is the first recorded incident of avian influenza exposure in a wild raccoon. We suggest that raccoons may play a role in the transmission of avian influenza viruses and in compromising biosecurity efforts at poultry operations.

Serologic Evidence of Avian Influenza (H4N6) Exposure in a Wild-Caught Raccoon

http://www.bioone.org/doi/abs/10.1637/8459-082708-ResNote.1?journalCode=avdi

Growing concerns about avian influenza, and its effect on agriculture and human health, have highlighted the need to understand the role of wildlife in maintaining and spreading the virus. We surveyed the wildlife inhabiting a poultry farm with recent H3N6 and H4N6 avian influenza virus exposure in Pennsylvania, U.S.A. One raccoon (Procyon lotor) tested positive for H4N6 antibodies. This is the first recorded incident of avian influenza exposure in a wild raccoon. We suggest that raccoons may play a role in the transmission of avian influenza viruses and in compromising biosecurity efforts at poultry operations.

**gsgs** · September 19, 2010, 01:54 AM

Re: interesting recent avian viruses

several Hongkong poultry H6N1,H6N2 genomes from 2001-2003 were released.
e.g. A/Ck/HK/SF3/2001(H6N1)
It is similar in 7 segments to HK-flu from 1997, so apparantly reassorted
with H5N1 by exchanging HA.
Did this reassortment happen before the 1997 outbreak in Hongkong,
is it the reassortment which led to that outbreak ?
It seems so. E.g. the PB1 of SF3 is closer to A/Dk/HK/562/1979(H10N9),
the best matching PB1 from the 70s, than A/H//156/1997.
But I'm not so sure yet since we had these periods of low mutation
in China which can corrupt normal molecular-clock analyis.

Anyway, I think that probably there was H6N1 in HK poultry all the time
before 1997 and then it just picked up the HA from A/Gs/Gd/1996(H5N1),
so to form a strain much more virulent to chickens.

They should have deep-frozen some sick-chicken/duck-tissues from HK
from the 80s or 90s. We do have some HK-sequences from the 70s,
but almost nothing from 1980-1996.

The 2004 tree-sparrows study shoud be redone.
Find the places,species in China where flu
survives without mutating.

**gsgs** · January 17, 2012, 01:25 AM

Re: interesting recent avian viruses

A/Pekin duck/CA/P30/2006/03/06(H4N2)

Code:

 13 >A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151 1692 1497 1414  982  838   
  1:135,111,142,483,146,512, 83,123   A/Brevig Mission/1/1918                                  2280 2274 2151 1701 1497 1410  982  838
  2:128,115,115,486,150, 74, 78,286   A/blue goose/WI/711/1975                                 2280 2274 2151 1695 1497 1414  982  838
  3: 39, 49, 47,322, 52,485, 31, 33   A/duck/LA/17G/1987                                       2280 2274 2151 1710 1497 1410  982  838
 14: 26,  8,  7,123, 59, 11,  4,  9   A/mallard/CA/J-808/2006/12/06                             412 1008 1000  516  185 1238  982  838

 14 >A/mallard/CA/J-808/2006/12/06                             412 1008 1000  516  185 1238  982  838   
  1:121,101,139,478,102,512, 85,122   A/Brevig Mission/1/1918                                  2280 2274 2151 1701 1497 1410  982  838
  2: 96,107,110,470,102, 74, 76,286   A/blue goose/WI/711/1975                                 2280 2274 2151 1695 1497 1414  982  838
  3: 36, 32, 42,323,102,485, 33, 30   A/duck/LA/17G/1987                                       2280 2274 2151 1710 1497 1410  982  838
 13: 26,  8,  7,123, 59, 11,  4,  9   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151 1692 1497 1414  982  838

  3 >A/duck/LA/17G/1987                                       2280 2274 2151 1710 1497 1410  982  838   
  1:124, 98,135,490,146,390, 87,110   A/Brevig Mission/1/1918                                  2280 2274 2151 1701 1497 1410  982  838
  2:124,105, 98,484,159,479, 77,290   A/blue goose/WI/711/1975                                 2280 2274 2151 1695 1497 1414  982  838
 13: 39, 49, 47,322, 52,485, 31, 33   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151 1692 1497 1414  982  838
 14: 36, 32, 42,323,102,485, 33, 30   A/mallard/CA/J-808/2006/12/06                             412 1008 1000  516  185 1238  982  838

  1 >A/Brevig Mission/1/1918                                  2280 2274 2151 1701 1497 1410  982  838   
  2:105, 81,129,310,124,505, 52,278   A/blue goose/WI/711/1975                                 2280 2274 2151 1695 1497 1414  982  838
  3:124, 98,135,490,146,390, 87,110   A/duck/LA/17G/1987                                       2280 2274 2151 1710 1497 1410  982  838
 13:135,111,142,483,146,512, 83,123   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151 1692 1497 1414  982  838
 14:121,101,139,478,102,512, 85,122   A/mallard/CA/J-808/2006/12/06                             412 1008 1000  516  185 1238  982  838

  2 >A/blue goose/WI/711/1975                                 2280 2274 2151 1695 1497 1414  982  838   
  1:105, 81,129,310,124,505, 52,278   A/Brevig Mission/1/1918                                  2280 2274 2151 1701 1497 1410  982  838
  3:124,105, 98,484,159,479, 77,290   A/duck/LA/17G/1987                                       2280 2274 2151 1710 1497 1410  982  838
 13:128,115,115,486,150, 74, 78,286   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151 1692 1497 1414  982  838
 14: 96,107,110,470,102, 74, 76,286   A/mallard/CA/J-808/2006/12/06                             412 1008 1000  516  185 1238  982  838


 16 >A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    3 1520    3 1002  864   
  1:127,149,142,---,148,---, 52,122   A/Brevig Mission/1/1918                                  2280 2274 2151    3 1497    3  982  838
  2: 65,154,115,---,148,---, 47,288   A/blue goose/WI/711/1975                                 2280 2274 2151    3 1497    3  982  838
  3:125,154,130,---, 57,---, 88, 34   A/duck/LA/17G/1987                                       2280 2274 2151    3 1497    3  982  838
 11:164,107, 88,---,148,---, 66,115   A/mallard/New Zealand/527-11/2005                        2280  931 2151    3 1497    3  982  838
 15: 41, 28, 19,---,160,---, 25,289   A/N.shoveler/Int.Alaska/8BM3671/2008/09/25   1844  424 1115    3 1161    3  982  838
 13:135,159,136,---, 15,---, 84,  5   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    3 1497    3  982  838
 14:125,140,137,---, 48,---, 84, 13   A/mallard/CA/JN808/2006/12/06                             412 1008 1000    3  185    3  982  838

Code:

  1 >A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838   
  2:105, 81,129,---,124,---, 52,278   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
  3:124, 98,135,---,146,---, 87,110   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
 13:135,111,142,---,146,---, 83,123   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 14:121,101,139,---, 59,---, 85,122   A/mallard/CA/J-808/2006/12/06                             412 1008 1000    0  185    0  982  838
 15:111, 96,129,---,135,---, 51,281   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 16:127,149,142,---,148,---, 52,122   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864
 17:137,117,142,---,146,---, 84,122   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

  2 >A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838   
  1:105, 81,129,---,124,---, 52,278   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  3:124,105, 98,---,159,---, 77,290   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
 13:128,115,115,---,150,---, 78,286   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 14: 96,107,110,---, 64,---, 76,286   A/mallard/CA/J-808/2006/12/06                             412 1008 1000    0  185    0  982  838
 15: 61,101,107,---, 84,---, 42, 36   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 16: 65,154,115,---,148,---, 47,288   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864
 17:134,117,114,---,147,---, 77,284   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

  3 >A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838   
  1:124, 98,135,---,146,---, 87,110   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  2:124,105, 98,---,159,---, 77,290   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
 10: 96, 74,129,---,156,---, 94,103   A/mallard/New Zealand/223-31/2005                         476  336 2151    0 1497    0  982  838
 13: 39, 49, 47,---, 52,---, 31, 33   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 14: 36, 32, 42,---, 91,---, 33, 30   A/mallard/CA/JN808/2006/12/06                             412 1008 1000    0  185    0  982  838
 15:123,103,116,---,166,---, 86,289   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 16:125,154,130,---, 57,---, 88, 34   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864
 17: 46, 49, 50,---, 54,---, 32, 32   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

 10 >A/mallard/New Zealand/223-31/2005                         476  336 2151    0 1497    0  982  838   
  1: 94, 80,140,---,140,---, 73, 76   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  2: 85, 86,111,---,109,---, 64,286   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
  3: 96, 74,129,---,156,---, 94,103   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
  6:  8, 15, 24,---, 58,---, 16, 27   A/mallard/New Zealand/449-33/2004                        2280  748 2151    0 1497    0  982  838
 11:  2,  2, 26,---, 48,---, 41, 20   A/mallard/New Zealand/527-11/2005                        2280  931 2151    0 1497    0  982  838
 13: 94, 80,140,---,152,---, 94,119   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 14: 96, 86,134,---, 59,---, 92,117   A/mallard/CA/J-808/2006/12/06                             412 1008 1000    0  185    0  982  838
 15: 90, 65, 79,---,142,---, 70,278   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 16:104, 74, 91,---,157,---, 69,117   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864
 17: 96, 89,139,---,154,---, 93,117   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

 13 >A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838   
  1:135,111,142,---,146,---, 83,123   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  2:128,115,115,---,150,---, 78,286   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
  3: 39, 49, 47,---, 52,---, 31, 33   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
 10: 94, 80,140,---,152,---, 94,119   A/mallard/New Zealand/223-31/2005                         476  336 2151    0 1497    0  982  838
 14: 26,  8,  7,---, 26,---,  4,  9   A/mallard/CA/J-808/2006/12/06                             412 1008 1000    0  185    0  982  838
 15:131,120,128,---,171,---, 83,289   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 16:135,159,136,---, 15,---, 84,  5   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864
 17: 23, 15,  7,---, 11,---,  3, 10   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

 14 >A/mallard/CA/JN808/2006/12/06                             412 1008 1000    0  185    0  982  838   
  1:121,101,139,---, 59,---, 85,122   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  2: 96,107,110,---, 64,---, 76,286   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
  3: 36, 32, 42,---, 91,---, 33, 30   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
 13: 26,  8,  7,---, 26,---,  4,  9   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 15:116,115,147,---,117,---, 83,289   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 16:125,140,137,---, 32,---, 84, 13   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864
 17:  7,  2,  7,---, 26,---,  3,  1   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

 15 >A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838   
  1:111, 96,129,---,135,---, 51,281   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  2: 61,101,107,---, 84,---, 42, 36   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
  3:123,103,116,---,166,---, 86,289   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
 13:131,120,128,---,171,---, 83,289   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 14:116,115,147,---,117,---, 83,289   A/mallard/CA/J-808/2006/12/06                             412 1008 1000    0  185    0  982  838
 16: 42, 28, 19,---,160,---, 25,289   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864
 17:131,115,126,---,162,---, 82,288   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

 16 >A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864   
  1:127,149,142,---,148,---, 52,122   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  2: 65,154,115,---,148,---, 47,288   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
  3:125,154,130,---, 57,---, 88, 34   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
 13:135,159,136,---, 15,---, 84,  5   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 14:125,140,137,---, 32,---, 84, 13   A/mallard/CA/J-808/2006/12/06                             412 1008 1000    0  185    0  982  838
 15: 42, 28, 19,---,160,---, 25,289   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 17:134,162,134,---,  5,---, 82, 14   A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851

 17 >A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)            2301 2101 2196    0 1507    0  989  851   
  1:137,117,142,---,146,---, 84,122   A/Brevig Mission/1/1918                                  2280 2274 2151    0 1497    0  982  838
  2:134,117,114,---,147,---, 77,284   A/blue goose/WI/711/1975                                 2280 2274 2151    0 1497    0  982  838
  3: 46, 49, 50,---, 54,---, 32, 32   A/duck/LA/17G/1987                                       2280 2274 2151    0 1497    0  982  838
 13: 23, 15,  7,---, 11,---,  3, 10   A/pekin Dk/CA/P30/2006/03/06                             2280 2274 2151    0 1497    0  982  838
 14:  7,  2,  7,---, 26,---,  3,  1   A/mallard/CA/J-808/2006/12/06                             412 1008 1000    0  185    0  982  838
 15:131,115,126,---,162,---, 82,288   A/northern shoveler/Interior Alaska/8BM3671/2008/09/25   1844  424 1115    0 1161    0  982  838
 16:134,162,134,---,  5,---, 82, 14   A/northern pintail/CA/HKWF792/2007/11/28                 2293 2274 2209    0 1520    0 1002  864

Scientists look for precursor of 1918 flu virus - FluTrackers News and Information

http://www.flutrackers.com/forum/showthread.php?t=7400

since when is there influenza in humans ? - FluTrackers News and Information

http://www.flutrackers.com/forum/showthread.php?t=34185

A/duck/LA/17G/1987(H3N8)

A/Northern pintail/California/HKWF792/2007(H3N8),
which is a bit similar in segments 4,5,6,8, clearly reassorted.

segment 2 but not the others is closest to Brevig/1918.

the 1889 pandemic is assumed to have been H3N8
__________________

H3N8 was also in recent outbreaks in horses and dogs.
H3N8 is quite frequent in birds too, but birds have many
different serotypes.

However this H3N8 from 1987 is quite different to any other
known H3N8.
It gave segments 5,8 to the shoveler (edit:also 4,6)
__________________
nucleotide differences of A/duck/LA/17G/1987(H3N8) to other viruses
in 0/00 for the 8 segments:

A/Northern pintail/California/HKWF792/2007(H3N8) : 124,151,128,043,057,047,088,033
A/Brevig Mission/1918(H1N1) : 124,098,135,492,146,428,087,110
A/Kansas.../2007(H1N1) : 152,132,152,500,184,435,123,152
A/fowl plague/Rostock/1934(H7N1) : 143,156,103,441,152,413,095,110

Most recent common anchestor of 17G/1987 in PB1 with Brevig/1918 is ~1915
Most recent common anchestor in PB1 with Dk/Memphis/546/1974 is ~1945

**gsgs** · January 17, 2012, 03:41 AM

Re: interesting recent avian viruses

AT-scores (high-->mammalean)

Code:

5614  5592,5760,5708,5778,5357,5716,5213,5453,  -  >A/Index/early human/~1935(H1N1)
5574  5561,5659,5620,5802,5310,5751,5152,5465,  -  >A/Brevig Mission/1/1918(H1N1)
5611  5592,5703,5685,5837,5317,5829,5152,5465,  -  >A/Index/early swine/~1935(H1N1)

5505  5531,5659,5674,----,5220,----,5150,----,  -  >A/duck/Memphis/546/1974(H11N9)
5720  ----,----,----,5767,----,5652,----,----,  -  >A/Anas crecca/Spain/1384/2007(H1N1)
5506  5472,5642,5723,----,5214,----,5170,5584,  -  >A/Index/7 birds similar to BM18/~1975
5556  5417,5756,5535,5830,5285,5770,5110,5543,  -  >A/pintail/Alaska/20/2005(H12N5)
5569  5574,5753,5620,5696,5258,5594,5121,5719,  -  >A/mallard/Interior Alaska/2/2007(H4N6)
5560  5510,5732,5655,5655,5234,5659,5183,5649,  -  >A/pintail/Alaska/279/2005(H3N8)
5570  5547,5742,5656,5649,5226,5665,5216,5649,  -  >A/mallard/Alaska/715/2005(H3N8)
5737  5729,5798,5797,5821,5519,5986,5309,5745,  -  >A/duck/LA/17G/1987(H3N8)
5719  5692,5844,5885,5839,5524,5693,5295,5668   -  >A/Pekin duck/CA/P30/2006/03/06(H4N2)
5696  5697,5844,5878,----,5507,----,5288,5663  -     >A/cinnamon teal/CA/44287-325/2007/01/27(H3N8)

6087  6073,6167,6270,6199,5850,6176,5483,6187,  -  >A/equine/Lexington/1-1/1966(H7N7)
6016  ----,----,----,----,5814,6152,----,6150,  -  >A/equine/Prague/1-3/1956(H7N7)
5978  6091,5533,----,6216,5814,6713,5530,6191,  -  >A/equine/Prague/1-1/1956(H7N7)
5897  ----,----,----,----,5725,6142,5550,6191,  -  >A/equine/Prague/1-2/1956(H7N7)
5733  5594,5606,5735,6203,5267,6184,5570,5777,  -  >A/equine/Kentucky/1a/1975(H7N7)
5548  5526,5540,5652,5797,5272,5624,5131,5710,  -  >A/equine/Uruguay/1/1963(H3N8)
5733  5681,5728,5893,5959,5444,5890,5248,5849,  -  >A/swine/Chibi/01/2005/12/15(H3N8)

5621  5723,5743,5741,5543,5384,5687,5236,5627,  -  >1968//,182,CHN,A/Beijing/1/68
5615  5666,5751,5741,5584,5357,5673,5226,5675,  -  >1972//,1643,RUS,A/Udorn/307/72
5641  5710,5769,5788,5617,5357,5695,5241,5663,  -  >1979//,4199,THA,A/Bangkok/01/79
5643  5706,5756,5783,5673,5344,5702,5224,5675,  -  >1983//,5660,HKG,A/HK/14/83
5654  5701,5783,5783,5667,5384,5677,5259,5722,  -  >1989//,7852,CHN,A/Beijing/353/89
5665  5736,5773,5778,5720,5364,5702,5248,5746,  -  >1997/11/29,10924,USA,A/NY/503/97
5674  5728,5760,5736,5784,5437,5687,5243,5817,  -  >2007/02/06,14278,AUS,A/Brisbane/10/07

6087  6073,6167,6270,6199,5850,6176,5483,6187,  -  >A/equine/Lexington/1-1/1966(H7N7)
5990  6071,6179,6166,5774,5765,5746,6138,5964,  -  >B/Mississippi/UR06-0031/2007

5574  5561,5659,5620,5802,5310,5751,5152,5465,  -  >A/Brevig Mission/1/1918(H1N1)
5587  5578,5681,5639,5778,5310,5808,5142,5477,  -  >A/swine/Jamesburg/1942(H1N1)
5663  5684,5839,5741,5753,5370,5817,5158,5596,  -  >A/Denver/57(H1N1)
5691  5614,5848,5792,5978,5357,5851,5244,5489,  -  >A/New Jersey/1976(H1N1)
5669  5671,5826,5750,5843,5283,5810,5274,5584,  -  >A/Index/1977(H1N1)
5742  5820,5897,5834,5812,5384,5866,5366,5596,  -  >A/Kansas/UR06-0068/2007(H1N1)
5632  5526,5800,5578,5920,5377,5794,5285,5608,  -  >A/******/index/2009-02-01(H1N1)

this makes you wonder whether that virus evolves in mammals
3 samples known now, all from ducks : duck,Pekin duck,mallard
LA,CA,CA,1987,2006,2006

Code:

avian genomes with highest AT-score (out of 3131 genomes from genbank,Jan.2012)
---------------------------------------------------------------------------------------------------------------------------------

5732,5725,5657,5884,5350,5735,5050,5692, = 5641   >A/duck/Fujian/3193/2005//(H6N2)
5675,5831,5732,5729,5477,5475,5376,5525, = 5642   >A/rufous-necked stint/Japan/6KS0279/2006/09/09(H4N8)
5671,5822,5746,5736,5464,5489,5376,5525, = 5643   >A/slaty-backed gull/Japan/6KS0185/2006/07/26(H4N8)
5675,5831,5741,5747,5457,5489,5376,5525, = 5644   >A/rufous-necked stint/Japan/6KS0242/2006/09/02(H4N8)
5609,5809,5708,5837,5337,5765,5305,5572, = 5650   >A/duck/NY/13822/1995//(H3N8)
5714,5778,5736,5765,5397,5863,5193,5584, = 5668   >A/duck/Victoria/5384/2002//(H4N8)
5697,5778,5774,5778,5490,5957,5254,5704, = 5706   >A/duck/LA/17G/1987//(H3N8)
5723,5835,5862,5896,5384,5851,5234,5536, = 5714 *  >A/turkey/Kansas/4880/1980//(H1N1)
5728,5839,5862,5902,5384,5851,5244,5536, = 5717 *  >A/Ck/PA/35154/1991//(H1N1)
5684,5842,5862,5808,5490,5879,5264,5632, = 5719   >A/cinnamon teal/California/44287-325/2007/01/27(H3N8)
5692,5844,5885,5842,5524,5695,5295,5668, = 5719   >A/pekin duck/California/P30/2006/03/06(H4N2)
5666,5875,5853,5972,5424,5829,5264,5584, = 5727 *  >A/turkey/IA/21089-3/1992//(H1N1)
5697,5861,5853,5961,5410,5872,5274,5608, = 5734 *  >A/turkey/NC/19762/1988//(H1N1)
5697,5861,5853,5967,5430,5865,5264,5620, = 5736 *  >A/turkey/NC/17026/1988//(H1N1)

(* : poultry that caught a swine virus)

average AT-score of avian genomes
serotype,score,number of genomes

H9N2 5575 173
H6N2 5575 205
H5N1 5572 533
H6N1 5565 160
H5N2 5560 173
H7N2 5560 124
H1N1 5542 93
H3N8 5523 304
H4N6 5519 212
H7N3 5514 108
rest 5534 1049

score of H5N1-genomes by year:
2011 5578 12
2010 5582 25
2009 5579 21
2008 5582 40
2007 5579 79
2006 5579 95
2005 5569 143
2004 5561 75
2003 5550 19
2002 5543 11
2001 5548 6
2000 5557 1
1997 5537 3
1996 5556 1

AT-score by species:
chicken,duck,guinea fowl,gull,goose,mallard,pintail duck,quail,shorebird,shoveler,
swan,turkey,teal,turnstone,wigeon,rest
Ck 5570 513
Dk 5564 448
GF 5560 17
Gl 5540 19
Gs 5558 35
Ml 5534 804
Pt 5531 127
Qa 5552 30
Sb 5531 98
Sv 5527 120
Sw 5578 32
Tk 5547 107
Tl 5525 209
Ts 5532 92
Wg 5554 34
-- 5550 449

Sw 5578 32
Ck 5570 513

Dk 5564 448
GF 5560 17
Gs 5558 35
Wg 5554 34
Qa 5552 30
-- 5550 449
Tk 5547 107

Gl 5540 19

Ml 5534 804
Ts 5532 92
Pt 5531 127
Sb 5531 98
Sv 5527 120
Tl 5525 209

**mixin** · January 17, 2012, 08:27 AM

Re: interesting recent avian viruses

With your approval.. a few comments about this from our recent chat:

Sterten : i just found a new interesting avian virus
Sterten : A/Pekin Duck/California/2006
Sterten : http://www.ncbi.nlm.nih.gov/nuccore/CY053821?
Sterten: hmm, known since Dec.2009
Sterten: so, shortly after my last cloud-analysis

Sterten: it's similar to the 1984 17g virus ...A/Duck/LA/17G/1987
Sterten: which was thought to be a "singleton"
mixin: it must have been a domestic duck; were there more with it in the flock?
mixin: pekin ducks are raised for food?
Sterten: wild Pekin Ducks in CA ?
mixin: don't know
Sterten: http://www.ncbi.nlm.nih.gov/nuccore/EU871828? A/Duck/LA/17G/1987
mixin: Around 95% of duck meat consumed in the United States is Pekin duck
Sterten: LA=Louisiana ?
Sterten: that strain may give hints about 1918
Sterten: I thought it was extinct
Sterten: only 2 viruses, LA 1987 and CA 2006
mixin: LA probably does mean Louisiana
Sterten: so, in what species may the virus have hidden and survived for >100 years
Sterten: HA and NA are still reassorting

Sterten: 3rd one is: A/mallard/CA/J808/2006/12/06
Sterten: only partial
mixin177: Pekin is our very popular white duck
Sterten: domesticated ?
mixin: yes, domesticated

Sterten: A/mallard/CA/JN808/2006/12/06
Sterten: http://www.ncbi.nlm.nih.gov/nuccore/CY076830.1
Sterten: /host="mallard; gender M; age After hatch year"
Sterten: so,wild duck ?
Sterten: /country="USA: Gridley, CA"
Sterten: /note="has low uni-directional coverage"
Sterten: http://en.wikipedia.org/wiki/Gridley,_California, not on the coast
Sterten: so what does a mallard in Gridley
mixin: mallards like lakes and marshy areas, too
mixin: they don't need big bodies of water
Sterten: not mixing with other ducks ? for 100 years
mixin: I think they do associate with other ducks and geese; they may all swim together

Sterten: http://www.ncbi.nlm.nih.gov/nuccore/CY076830.1

Influenza A virus (A/duck/LA/17G/1987(H3N8)) segment 4 hemagglutinin ( - Nucleotide - NCBI

http://www.ncbi.nlm.nih.gov/nuccore/EU871828?

Influenza A virus (A/pekin duck/California/P30/2006(H4N2)) segment 4, - Nucleotide - NCBI

http://www.ncbi.nlm.nih.gov/nuccore/CY053821?

Sterten: /country="USA: Perris, CA". that was the Pekin duck
mixin1: Gridley is in Butte County
Sterten: distant from Gridley
Sterten: so presumably the strain is still prevalent in the common duck=mallard population
Sterten: but very rare

Sterten: 1987,2006,2006...but one in LA in 1987
Sterten: 3 out of thousands
Sterten: many mallard-flu-sequences from CA
Sterten: pacific flyway; CA--Alaska

mixin: so I've lost the point...
mixin: do you think it's old and rare?
mixin: or new and rare?
mixin: or just interesting?
Sterten: yes to all
Sterten: evolution ...first old then new
Sterten: the common ancestor
Sterten: in segment 2
Sterten: -say-
Sterten: with any other current flu-A
Sterten: is ~1900 or 1850; I haven't yet examined

Sterten: other current avian flu is more distant to 1918 in segment 2
Sterten: and probably other segments
Sterten: we had 7 voruses in the 70s from that close 1918-strain now extinct
Sterten: that 7-bird-70s segment 2 is still different from gridley-flu
Sterten: common anchestor <1900
Sterten (12:39:20 AM): 13 >A/pekin Dk/CA/P30/2006/03/06 2280 2274 2151 1692 1497 1414 982 838
1:135,111,142,483,146,512, 83,123 A/Brevig Mission/1/1918 2280 2274 2151 1701 1497 1410 982 838
2:128,115,115,486,150, 74, 78,286 A/blue goose/WI/711/1975 2280 2274 2151 1695 1497 1414 982 838
3: 39, 49, 47,322, 52,485, 31, 33 A/duck/LA/17G/1987 2280 2274 2151 1710 1497 1410 982 838

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