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Epilepsy in children unrelated to pandemic flu vaccination

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  • Epilepsy in children unrelated to pandemic flu vaccination

    Pandemic influenza vaccination is not associated with an increased risk of epilepsy in children, according to an analysis conducted on data collected during an H1N1 pandemic in Norway.
    ?We have previously shown that vaccination against pandemic influenza increased the risk of febrile seizures in children, although to a lower degree than influenza infection, and there have been concerns about an association with later epilepsy,? Siri E. H?berg, MD, PhD, from the Norwegian Institute of Public Health, Oslo, Norway, and colleagues wrote. ?There has been increasing focus on the role of infections and immunologic factors, not only in febrile seizures, but also in the etiology of epilepsy.?

    To examine whether vaccination during an influenza pandemic contributed to an increased risk of epilepsy in children, the researchers analyzed data collected between 2006 and 2014 in children younger than 18 years in Norway. Hazard ratios for epilepsy after influenza immunization were estimated using Cox regression models. H?berg and colleagues then conducted a self-controlled case series analysis to approximate the incidence rate of epilepsy after pandemic vaccination within specific risk periods.

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    Pandemic influenza vaccination is not associated with an increased risk of epilepsy in children, according to an analysis conducted on data collected during an H1N1 pandemic in Norway.“We have previously shown that vaccination against pandemic influenza increased the risk of febrile seizures in children, although to a lower degree than influenza infection, and there have been concerns about



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