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50-year-old flu virus model revamped, revealing pandemic prediction possibilities

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  • 50-year-old flu virus model revamped, revealing pandemic prediction possibilities

    The discovery, reported online and in a coming print issue of the journal Nucleic Acids Research, reveals loopholes in the way the virus packages its genetic material. When one strain of flu co-mingles with another strain inside a cell, these loopholes allow the viruses to swap genetic material and give rise to new strains of flu. Knowing these loopholes and how they interact with each other could give scientists the opportunity to better predict pandemics and find new ways to disrupt the flu virus.



    The scientific textbook depiction of the flu virus is about to get a facelift, due to a University of Pittsburgh School of Medicine team's discovery that a model of the influenza genome architecture untouched since the 1970s isn't so perfect after all.

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