Tweet
A new mouse model of early Ebola virus (EBOV) infection has shown National Institutes of Health (NIH) scientists and colleagues how early responses of the immune system can affect development of EBOV disease. The model could help identify protective immune responses as targets for developing human EBOV therapeutics.
Scientists from NIH's National Institute of Allergy and Infectious Diseases led the study with colleagues from the University of Washington and Columbia University.
The scientists analyzed signals that host cells use to alert the immune system to EBOV infection, and the immune system's responses. They focused on signaling events that begin within hours of a virus infection and involve the cellular mitochondrial antiviral signaling protein or MAVS.
...
Scientists from NIH's National Institute of Allergy and Infectious Diseases led the study with colleagues from the University of Washington and Columbia University.
The scientists analyzed signals that host cells use to alert the immune system to EBOV infection, and the immune system's responses. They focused on signaling events that begin within hours of a virus infection and involve the cellular mitochondrial antiviral signaling protein or MAVS.
...
Comment