New Study Finds Wild Pikas Are Natural Mammalian Hosts To H5N1 Avian Influenza Virus

[mixin]

Re: New Study Finds Wild Pikas Are Natural Mammalian Hosts To H5N1 Avian Influenza Virus

so, how did the virus(-part) come from
Nigeria, 23.Jan.2007 to
Qinghai lake region, 02.Dec.2007

Migratory birds?

[gsgs]

Re: New Study Finds Wild Pikas Are Natural Mammalian Hosts To H5N1 Avian Influenza Virus

looks like another recombination in the PB1 from Nigeria !

The first part (~800 Nucleotides) is from A/Ck/Henan/12/2004(H5N1)

repeating the best matches for the 8 segments from above:

A/Pika/Qinghai/HMH/2007/12/03(H5N1)
---------------------------------
PB2: 2,A/Dk/Hunan/5106/2005(H5N1)
PB1: 22,A/Ck/Nigeria/1071-15/2007(H5N1)
PA : 28,A/Dk/Guangxi/288/2006(H5N1)
HA : 20,A/MagpieRobin/HK/1097/2008(H5N1)
NP : 16,A/PeregrineFalcon/HK/2142/2008(H5N1)
NA : 14,A/Ck/Guangxi/463/2006(H5N1)
M : 9,A/PeregrineFalcon/HK/2142/2008(H5N1)
NS : 2,A/Dk/Guangxi/4428/2005(H5N1)




That reminds me to our analysis about the Qinghai-lake viruses which
showed much reassortment,recombination, a whole viral mess

http://www.flutrackers.com/forum/showthread.php?t=17845

>A/Ck/Nigeria/1071-15/07,01,23(H5N1) , segment 2
>A/pika/Qinghai/HMH/07,12,03(H5N1) , segment 2

------------------------.................................... 0 
....o....................................................... 1 
..o........o..o............................................. 3 
...............................................o........o... 2 
..........................o....................o............ 2 
............................................................ 0 
.....o...................................o.................. 2 
..........................o................................. 1 
............................................................ 0 
...................................o..o....................o 3 
..........o...o.oo................................o......... 5 
......................................o..................... 1 
.........o.................................................. 1 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
................o........................................... 1 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
............................................................ 0 
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..................------------------------------------------ 0 
--- 22

[gsgs]

Re: New Study Finds Wild Pikas Are Natural Mammalian Hosts To H5N1 Avian Influenza Virus

the recombined virus is in 4 different pika viruses from 4 different locations !


they should let some foreign team+lab redo the pika sampling
and confirm the sequences.

It's important enough.
Too bad that we already lost 2 years due to the publishing delays

[Gert van der Hoek]

Re: New Study Finds Wild Pikas Are Natural Mammalian Hosts To H5N1 Avian Influenza Virus

so, how did the virus(-part) come from
Nigeria, 23.Jan.2007
to
Qinghai lake region, 02.Dec.2007

Just guessing: it went by plane to Nigeria (chicks) and returned with migratory birds ?

[gsgs]

Re: New Study Finds Wild Pikas Are Natural Mammalian Hosts To H5N1 Avian Influenza Virus

paper in .pdf, 22 pages:

http://jvi.asm.org/cgi/reprint/JVI.00793-09v1

zero hits for recombination or reassortment