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United Kingdom reports 25% ICU beds occupancy due to H1N1 (2009) influenza, bacterial superinfections and 2% of oseltamivir resistance, said latest WHO Report (Jan 15 2011)

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  • United Kingdom reports 25% ICU beds occupancy due to H1N1 (2009) influenza, bacterial superinfections and 2% of oseltamivir resistance, said latest WHO Report (Jan 15 2011)

    [Source: World Health Organization, full page: http://www.who.int/csr/disease/influ.../en/index.html - http://www.flutrackers.com/forum/sho...72&postcount=1. Edited.]

    Influenza update - 14 January 2011

    Influenza - Update 125

    14 January 2011


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    Summary:

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    In the United Kingdom, severe and fatal cases are increased compared to 2 weeks ago, associated predominantly with influenza A (H1N1) 2009 and less commonly with influenza type B.

    Currently, 25% of intensive care beds in the U.K. are occupied by influenza patients.

    Notably, the Chief Medical Officer has issued an alert to clinicians warning of increasing rates of bacterial infections often associated with influenza (S. pneumoniae, Group A streptococcus, and meningococcus), though the association with the current influenza circulation is still under investigation.
    (...)

    Europe:

    The United Kingdom (U.K.) continues to report high rates of ILI and influenza-related hospitalizations.

    Currently approximately 25% of intensive care beds are occupied by influenza cases and 112 influenza-related deaths have been reported.

    95 of 100 fatal cases from which the virus has been sub-typed have been H1N1 (2009) related and the other 5, influenza type B.

    The majority of severe and fatal cases have been between the ages of 15 and 64 years; only 16% of fatal cases were over the age of 64 years.

    78% of the fatal cases for which there are data had an underlying risk condition.
    Of note, the Chief Medical Officer of the U.K. has issued an alert to clinicians noting recent increases in some bacterial infections that are sometimes seen as co-infections with influenza, particularly S. pneumoniae, invasive Group A streptococcus, and meningococcal disease.

    The association of this increase with the current influenza transmission is unclear and is under investigation.

    Two percent (17/811) H1N1 (2009) viruses tested in the U.K. have been found to carry the H275Y mutation which confers resistance to the antiviral drug oseltamivir.
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