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Week 15: Week 04.04.2016-10.04.2016
Influenza and ARI morbidity data
Epidemiological data showed decrease of influenza activity in Russia in comparison with previous week. Tthe nationwide ILI & ARI morbidity level (51.9 per 10 000 of population) was below the national baseline (69.5 per 10 000) by 25.3%.
ILI and ARI epidemic thresholds were not exceeded in all of 59 cities collaborating with two WHO NICs in Russia. Influenza.
...
Cumulative number of diagnosed influenza cases
Laboratory diagnosis data. Results of influenza laboratory diagnosis by different tests were submitted by 52 RBLs and two WHO NICs. According to these data as a result of 1940 patients investigation the overall proportion of respiratory samples positive for influenza virus was estimated as 274 (14.1%) including 128 (46.8%) influenza A(H1N1)pdm09 cases, 23 (8.4%) influenza A(H3N2) cases, 16 (5.8%) influenza A cases and 107 (39.1%) influenza B cases.
... Conclusion
Influenza and ARI morbidity data. Influenza activity decreased on the week 15.2016. The nationwide ILI & ARI morbidity level (51.9 per 10 000 of population) was below the national baseline by 25.3%.
Etiology of ILI & ARI morbidity. As a result of investigation of 1940 patients in 52 cities of Russia the overall proportion of respiratory samples positive for influenza in traditional surveillance system was estimated as 14.1%. Influenza A(H1N1)pdm09 was detected in 46.8%, influenza A(H3N2) - in 8.4% and influenza B in 39.1% of influenza cases.
The overall proportion of respiratory samples tested positive for parainfluenza, adenovirus and RSV was estimated in total as 9.6% (PCR) and 23.4% (IFA) of investigated samples.
In sentinel surveillance system clinical samples from 46 SARI and 50 ILI/ARI patients were investigated by rRT-PCR. 9(19.6%) influenza cases were detected includin52 influenza A(H1N1)pdm09 and 4 influenza B cases. A total 5 (10.0%) influenza cases including 3 influenza A(H1N1)pdm09 and 2 influenza B cases were detected among ILI/ARI patients.
Antigenic characterization. Totally 438 influenza viruses including 392 influenza A(H1N1)pdm09 viruses, 17 influenza A(H3N2) strains and 29 influenza B viruses were characterizated antigenically in two NICs of Russia since the beginning of the season. Influenza A(H1N1)pdm09 strains were related closely to influenza A/California/07/09 virus. 17 influenza A(H3N2) strains were similar to influenza A/Hong-Kong/5738/2014 virus, with antiserum to influenza A/Switzerland/9715293/2013 they reacted up to 1/4 - 1/8 of homological titer in HI. 28 investigated influenza B viruses belonged to Victorian lineage and antigenically were similar to influenza B/Brisbane/60/2008 reference strain reacting with antiserum to it up to 1 - 1/8 of homological titer in HI. One influenza B virus was similar to influenza B/Massachusetts/02/2012 reference strains and belonged to Yamagata lineage.
Genetic characterization. 64 investigated influenza A(H1N1)pdm09 virus strains were A/South Africa/3626/2013-like. All viruses bear clade 6B specific mutations in HA (S84N, S162+N and I216T) and formed new genetic group according to phylogenetic analysis. Two A(H1N1)pdm09 sequence obtained directly from autopsy sample showed the presence of additional mutation D222G in HA1. Data on 54 influenza strains presented in GISAID base data. Two influenza B viruses belong to clade 1A B/Brisbane/60/2008.
Susceptibility to antiviral drugs. According to genetic investigations of NA and M gene of 54 influenza A(H1N1)pdm09 all viruses were susceptible to oseltamivir and resistant to rimantadine. 72 influenza A(H1N1)pdm09 strains and 5 influenza B viruses were susceptibility to oseltamivir according to Munana test.
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http://www.influenza.spb.ru/en/influ...mic_situation/
Influenza and ARI morbidity data
Epidemiological data showed decrease of influenza activity in Russia in comparison with previous week. Tthe nationwide ILI & ARI morbidity level (51.9 per 10 000 of population) was below the national baseline (69.5 per 10 000) by 25.3%.
ILI and ARI epidemic thresholds were not exceeded in all of 59 cities collaborating with two WHO NICs in Russia. Influenza.
...
Cumulative number of diagnosed influenza cases
Laboratory diagnosis data. Results of influenza laboratory diagnosis by different tests were submitted by 52 RBLs and two WHO NICs. According to these data as a result of 1940 patients investigation the overall proportion of respiratory samples positive for influenza virus was estimated as 274 (14.1%) including 128 (46.8%) influenza A(H1N1)pdm09 cases, 23 (8.4%) influenza A(H3N2) cases, 16 (5.8%) influenza A cases and 107 (39.1%) influenza B cases.
... Conclusion
Influenza and ARI morbidity data. Influenza activity decreased on the week 15.2016. The nationwide ILI & ARI morbidity level (51.9 per 10 000 of population) was below the national baseline by 25.3%.
Etiology of ILI & ARI morbidity. As a result of investigation of 1940 patients in 52 cities of Russia the overall proportion of respiratory samples positive for influenza in traditional surveillance system was estimated as 14.1%. Influenza A(H1N1)pdm09 was detected in 46.8%, influenza A(H3N2) - in 8.4% and influenza B in 39.1% of influenza cases.
The overall proportion of respiratory samples tested positive for parainfluenza, adenovirus and RSV was estimated in total as 9.6% (PCR) and 23.4% (IFA) of investigated samples.
In sentinel surveillance system clinical samples from 46 SARI and 50 ILI/ARI patients were investigated by rRT-PCR. 9(19.6%) influenza cases were detected includin52 influenza A(H1N1)pdm09 and 4 influenza B cases. A total 5 (10.0%) influenza cases including 3 influenza A(H1N1)pdm09 and 2 influenza B cases were detected among ILI/ARI patients.
Antigenic characterization. Totally 438 influenza viruses including 392 influenza A(H1N1)pdm09 viruses, 17 influenza A(H3N2) strains and 29 influenza B viruses were characterizated antigenically in two NICs of Russia since the beginning of the season. Influenza A(H1N1)pdm09 strains were related closely to influenza A/California/07/09 virus. 17 influenza A(H3N2) strains were similar to influenza A/Hong-Kong/5738/2014 virus, with antiserum to influenza A/Switzerland/9715293/2013 they reacted up to 1/4 - 1/8 of homological titer in HI. 28 investigated influenza B viruses belonged to Victorian lineage and antigenically were similar to influenza B/Brisbane/60/2008 reference strain reacting with antiserum to it up to 1 - 1/8 of homological titer in HI. One influenza B virus was similar to influenza B/Massachusetts/02/2012 reference strains and belonged to Yamagata lineage.
Genetic characterization. 64 investigated influenza A(H1N1)pdm09 virus strains were A/South Africa/3626/2013-like. All viruses bear clade 6B specific mutations in HA (S84N, S162+N and I216T) and formed new genetic group according to phylogenetic analysis. Two A(H1N1)pdm09 sequence obtained directly from autopsy sample showed the presence of additional mutation D222G in HA1. Data on 54 influenza strains presented in GISAID base data. Two influenza B viruses belong to clade 1A B/Brisbane/60/2008.
Susceptibility to antiviral drugs. According to genetic investigations of NA and M gene of 54 influenza A(H1N1)pdm09 all viruses were susceptible to oseltamivir and resistant to rimantadine. 72 influenza A(H1N1)pdm09 strains and 5 influenza B viruses were susceptibility to oseltamivir according to Munana test.
Download PDF version
http://www.influenza.spb.ru/en/influ...mic_situation/
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