Germany Flu Season 2014-2015 Reports from the Robert Koch Institute

[Ronan Kelly]

Week 9 (02.21. To 27.02.2015)
Summary evaluation of the epidemiological situation
The activity of acute respiratory illness (ARE) is nationwide in the 9th calendar week (CW) in 2015
compared to last week remained stable. The values of the Praxis index were strong overall in the field
ARE increased activity.

The National Reference Center (NRC) for influenza were in the 9th KW 2015 172 (73%) of 237
submitted Sentinel samples identified respiratory viruses. In 144 (61%) samples were Influenza viruses,
in 16 (7%), respiratory syncytial (RS) virus in ten (4%) rhinoviruses, in six (3%) adenoviruses
and in four (2%) human metapneumoviruses (hMPV) detected.
After Infection Protection Act (IfSG) were used for the reporting week 9. (MW) in 2015 and so far 9,520 since
With 40 MW in 2014 were sent to 38,455 laboratory-confirmed clinical influenza cases to the RKI
(Data as of 03.03.2015).
The influenza-positive rate in the NRZ and the greatly increased ARE activity continue to show a high
Influenza activity in Germany. The remaining stable compared to last week of practice index values
could be an indication that the highlight of this year's flu season has been reached.

Acute respiratory diseases (ARE)
The activity of acute respiratory illness (ARE) is nationwide in the 9th KW 2015 compared to
Previous week remained stable. The praxis index was whole and in all AGI-regions in the area
ARE greatly increased activity (Table 1; Fig. 1.).
...
Reporting data for the Infection Protection Act (IfSG)
Previously were 9,520 laboratory-confirmed clinical influenza cases to the RKI for 9 MW 2015
Submitted: 6,589 cases with non subtypisierter influenza A, 618 cases of influenza A (H1N1) pdm09, 298
Cases of influenza A (H3N2), 453 cases of undifferentiated by influenza A or B and 1,562 cases with
Influenza B (Tab. 4). In 1,581 (17%) patients reported that they were hospitalized.
Since 2014, a total of 40 MW 38,455 laboratory-confirmed clinical influenza cases in
RKI transmitted. In 6,025 (16%) cases had indicated that they were hospitalized (data
03.03.2015).
So far, 74 deaths were transmitted with influenza infection at the RKI, including 49 cases with
not subtypisierter influenza A, four cases of influenza A (H3N2), twelve cases with influenza
A (H1N1) pdm09, three cases without differentiation of influenza A and B, and two cases with influenza B.
In addition, four clinical-epidemiological confirmed deaths have been disclosed in connection
associated with influenza outbreaks in nursing homes.
The different distribution of the identified influenza A subtypes in the AGI-Sentinel and the
Reporting data can be, among other things due to the fact that after the 2009 pandemic significantly more PCR for
Established subtyping of influenza A (H1N1) pdm09 as for A (H3N2) or integrated into multiplex PCR
were. The distribution of the circulating in the population influenza types and subtypes is in AGISentinel
better represented.
...

https://influenza.rki.de/Wochenberichte/2014_2015/2015-09.pdf

[Ronan Kelly]

Week 10 (28.02. To 06.03.2015)
Summary evaluation of the epidemiological situation
The activity of acute respiratory illness (ARE) is nationwide in the 10th calendar week (CW) in 2015
decreased compared to the previous week. The values of the Praxis index were a total of continues in the area
ARE greatly increased activity.

The National Reference Center (NRC) for influenza were in the 10 KW 2015 172 (71%) of 242
submitted Sentinel samples identified respiratory viruses. In 136 (56%) samples were influenza viruses,
in each of 18 (7%), respiratory syncytial (RS) - and rhinoviruses in four (2%) and adenoviruses in
five (2%) human metapneumoviruses (hMPV) detected.
After Infection Protection Act (IfSG) were used for the reporting week 10. (MW) in 2015 and since 7600 until now
With 40 MW in 2014 were sent to 47,679 laboratory-confirmed clinical influenza cases to the RKI
(Data as of 10.03.2015).
The significant drop compared to last week values of the index and practice of consultation incidence
and the slightly lower positive rate in the NRZ indicate that the peak of the
this year's flu season in 9th KW has been reached. Influenza activity in Germany, despite the
declining trends continue at a high level.

Acute respiratory diseases (ARE)
The activity of acute respiratory illness (ARE) is nationwide in the 10th KW 2015 compared to
Previous week declined. The praxis index was in the AGI large regions North (West) and East in
Range greatly increased ARE activity. In the AGI large regions south and center (West), the values decreased
in the area significantly increased ARE activity (Table 1; Fig. 1.).
...
Reporting data for the Infection Protection Act (IfSG)
Previously were 7,600 laboratory-confirmed clinical influenza cases to the RKI for 10 MW in 2015
Submitted: 4,892 cases with non subtypisierter influenza A, 380 cases of influenza A (H1N1) pdm09, 187
Cases of influenza A (H3N2), 342 cases of undifferentiated by influenza A or B and 1,799 cases
with influenza B (Tab. 4). In 1,235 (16%) patients reported that they were hospitalized.
Since 2014, a total of 40 MW 47,679 laboratory-confirmed clinical influenza cases in
RKI transmitted. In 7,563 (16%) cases had indicated that they were hospitalized (data
03.10.2015).
So far, 109 deaths were transmitted with influenza infection at the RKI, including 68 cases with
not subtypisierter influenza A, five cases of influenza A (H3N2), 17 cases of influenza A (H1N1) pdm09,
nine cases without differentiation by influenza A or B, and six cases with influenza B. Moreover, were
received four clinical-epidemiological confirmed deaths associated with influenza outbreaks
are in nursing homes.
The different distribution of the identified influenza A subtypes in the AGI-Sentinel and the
Reporting data can be, among other things due to the fact that after the 2009 pandemic significantly more PCR for
Established subtyping of influenza A (H1N1) pdm09 as for A (H3N2) or integrated into multiplex PCR
were. The distribution of the circulating in the population influenza types and subtypes is in AGISentinel
better represented.
...

https://influenza.rki.de/Wochenberichte/2014_2015/2015-10.pdf

[Ronan Kelly]

Week 11 (03.07. To 03.13.2015)
Summary evaluation of the epidemiological situation
The activity of acute respiratory illness (ARE) is nationwide in the 11th calendar week (CW) in 2015
decreased compared to the previous week. The values of the Praxis index were a total of in the area clearly
ARE increased activity.

The National Reference Center (NRC) for influenza were in the 11 KW 2015 135 (68%) of 199
submitted Sentinel samples identified respiratory viruses. In 100 (50%) samples were Influenza viruses,
in 22 (11%), respiratory syncytial (RS) virus in seven (4%) rhinoviruses, in five (3%) human
Metapneumoviruses (hMPV) and detected in three (2%) adenoviruses.
After Infection Protection Act (IfSG) were used for the 11 week reporting (MW) in 2015 and so far 5,805 since
With 40 MW in 2014 were sent to 55,212 laboratory-confirmed clinical influenza cases to the RKI
(Data as of 03.17.2015).
The fall after the 9th KW values of the index and practice of consultation incidence and easily
lower positive rate in the NRZ indicate that the highlight of this year's flu season
has been exceeded. Influenza activity in Germany, despite the declining trends continue
an elevated level.

Acute respiratory diseases (ARE)
The activity of acute respiratory illness (ARE) is nationwide in the 11th KW 2015 compared to
Previous week declined. The praxis index was in the AGI Greater Region East nor in the area strongly
ARE increased activity. In the AGI large regions south and north (west), the values decreased to the
Level significantly increased ARE activity. In the United AGI Region (West), the value for the lay
Practice index in the range moderately elevated ARE activity (Table 1; Fig. 1.).
...
Reporting data for the Infection Protection Act (IfSG)
Previously were 5,805 laboratory-confirmed clinical influenza cases to the RKI for 11 MW in 2015
Submitted: 3,175 cases with non subtyped influenza A, 313 cases of influenza A (H1N1) pdm09, 137
Cases of influenza A (H3N2), 180 cases of undifferentiated by influenza A or B and 2,000 cases
with influenza B (Tab. 4). In 875 (15%) patients reported that they were hospitalized.
Since 2014, a total of 40 MW 55,212 laboratory-confirmed clinical influenza cases in
RKI transmitted. In 8,785 (16%) cases had indicated that they were hospitalized (data
17.03.2015).
So far, 148 deaths with influenza infection were sent to the RKI, including 92 cases with
not subtypisierter influenza A, seven cases of influenza A (H3N2), 22 cases with influenza
A (H1N1) pdm09, 14 cases without differentiation by influenza A or B, and nine cases with influenza B.
In addition, four clinical-epidemiological confirmed deaths have been disclosed in connection
associated with influenza outbreaks in nursing homes.
The different distribution of the identified influenza A subtypes in the AGI-Sentinel and the
Reporting data can be, among other things due to the fact that after the 2009 pandemic significantly more PCR for
Established subtyping of influenza A (H1N1) pdm09 as for A (H3N2) or integrated into multiplex PCR
were. The distribution of the circulating in the population influenza types and subtypes is in AGISentinel
better represented.
...

https://influenza.rki.de/Wochenberichte/2014_2015/2015-11.pdf

[Ronan Kelly]

Week 12 (03.14. To 03.20.2015)
Summary evaluation of the epidemiological situation

The activity of acute respiratory illness (ARE) is nationwide in the 12th calendar week (CW) in 2015
decreased compared to the previous week. The values of the Praxisindex were generally moderate in the field
ARE increased activity.

The National Reference Center (NRC) for influenza were in the 12 KW 2015. 82 (59%) of 139
submitted Sentinel samples identified respiratory viruses. In 64 (46%) samples were Influenza viruses,
in ten (7%), respiratory syncytial (RS) virus in five (4%) human metapneumoviruses (hMPV),
detected in four (3%) and in only three rhinoviruses (2%) adenoviruses.
After Infection Protection Act (IfSG) were used for the 12 week reporting (MW) in 2015 and so far 3,963 since
With 40 MW in 2014 were sent to 60,588 laboratory-confirmed clinical influenza cases to the RKI
(Data as of 24.03.2015).
Influenza activity in Germany is despite the declining trends continue on a
elevated level.

Acute respiratory diseases (ARE)
The activity of acute respiratory illness (ARE) is nationwide in the 12th KW 2015 compared to
Previous week declined. The practice index was in the AGI Greater Region East at the level significantly increased
ARE activity. In the other three major regions AGI values for the Praxisindex in the area were slightly
elevated ARE activity (Table 1; Fig. 1.).
...
Financial data for the Infection Protection Act (IfSG)
Previously were 3,963 laboratory-confirmed clinical influenza cases to the RKI for 12 MW in 2015
Submitted: 1,684 cases with non subtypisierter influenza A, 189 cases of influenza A (H1N1) pdm09, 75
Cases of influenza A (H3N2), 108 cases of undifferentiated by influenza A or B and 1,907 cases
with influenza B (Tab. 4). In 535 (13%) patients reported that they were hospitalized.
Since 2014, a total of 40 MW 60,588 laboratory-confirmed clinical influenza cases in
RKI transmitted. In 8,829 (15%) cases had indicated that they were hospitalized (data
03.24.2015).
So far, 181 deaths were transmitted with influenza infection at the RKI, including 117 cases with
not subtypisierter influenza A, seven cases of influenza A (H3N2), 24 cases with influenza
A (H1N1) pdm09, 15 cases without differentiation by influenza A or B, and 13 cases with influenza B.
In addition, five clinical-epidemiological confirmed deaths have been disclosed in connection
associated with influenza outbreaks in nursing homes.
The different distribution of the identified influenza A subtypes in the AGI-Sentinel and the
Reporting data can be, among other things due to the fact that after the 2009 pandemic significantly more PCR for
Established subtyping of influenza A (H1N1) pdm09 as for A (H3N2) or integrated into multiplex PCR
were. The distribution of the circulating in the population influenza types and subtypes is in AGISentinel
better represented.
...

https://influenza.rki.de/Wochenberichte/2014_2015/2015-12.pdf

[Ronan Kelly]

Week 13 (03.21. To 27.03.2015)
Summary evaluation of the epidemiological situation

The activity of acute respiratory illness (ARE) is nationwide in the 13th calendar week (CW) in 2015
decreased compared to the previous week. The values of the Praxis index were a total in the area slightly
ARE increased activity.

The National Reference Center (NRC) for influenza were in the 13 KW 2015. 77 (58%) of 132
submitted Sentinel samples identified respiratory viruses. In 53 (40%) samples were Influenza viruses,
in four (3%), respiratory syncytial (RS) virus in five (4%) human metapneumoviruses (hMPV), in
nine (7%) and adenoviruses demonstrated in eleven (8%) rhinoviruses.
After Infection Protection Act (IfSG) were used for the 13 week reporting (MW) in 2015 and so far 2,884 since
With 40 MW in 2014 were sent to 64,416 laboratory-confirmed clinical influenza cases to the RKI
(Data as of 31.03.2015).
Influenza activity in Germany is despite the declining trends are still at a slightly
elevated level.

Acute respiratory diseases (ARE)
The activity of acute respiratory illness (ARE) is nationwide in the 13th KW 2015 compared to
Previous week declined. The practice index was in the AGI Greater Region East at the level of moderately elevated
ARE activity. In the other three major regions AGI values for the index in the practice area were slightly
elevated ARE activity (Table 1; Fig. 1.).
...
Reporting data for the Infection Protection Act (IfSG)
Previously were 2,884 laboratory-confirmed clinical influenza cases to the RKI for 13 MW in 2015
Submitted: 920 cases with non subtypisierter influenza A, 122 cases of influenza A (H1N1) pdm09, 39 cases
with influenza A (H3N2), 110 cases of undifferentiated by influenza A or B and 1,693 cases of influenza
B (Tab. 4). In 392 (14%) patients reported that they were hospitalized.
Since 2014, a total of 40 MW 64,416 laboratory-confirmed clinical influenza cases in
RKI transmitted. At 10,119 (16%) cases had indicated that they were hospitalized (data
31.03.2015).

So far, 200 deaths were transmitted with influenza infection at the RKI, including 127 cases with
not subtypisierter influenza A, seven cases of influenza A (H3N2), 28 cases with influenza
A (H1N1) pdm09 and 17 cases without differentiation by influenza A or B, and 16 cases with influenza B.
In addition, five clinical-epidemiological confirmed deaths have been disclosed in connection
associated with influenza outbreaks in nursing homes.
The different distribution of the identified influenza A subtypes in the AGI-Sentinel and the
Reporting data can be, among other things due to the fact that after the 2009 pandemic, the PCR for subtyping
for influenza A (H1N1) is established pdm09 much wider than for A (H3N2), or integrated in multiplex PCR
has become. The distribution of the circulating in the population influenza types and subtypes is in AGISentinel
better represented.
...

https://influenza.rki.de/Wochenberichte/2014_2015/2015-13.pdf

[Ronan Kelly]

Week 14 (28.03. To 04.03.2015)
Summary evaluation of the epidemiological situation

The activity of acute respiratory illness (ARE) is nationwide in the 14th calendar week (CW) in 2015
compared to last week dropped significantly. The values of the Praxisindex were a total in the field of
ARE-background activity and reached the normal level for the season.

The National Reference Center (NRC) for influenza were in the 14 KW 2015. 35 (71%) of 49
submitted Sentinel samples identified respiratory viruses. In 23 (47%) samples were Influenza viruses,
in four (8%), respiratory syncytial (RS) virus, human in three (6%) metapneumoviruses (hMPV)
and detected in six (12%) rhinoviruses.
After Infection Protection Act (IfSG) were used for the 14 week reporting (MW) in 2015 and so far 1,388 since
With 40 MW in 2014 were sent to 66,256 laboratory-confirmed clinical influenza cases to the RKI
(Data as of 04.08.2015).
Part of acute respiratory illness caused by influenza viruses yet.

Acute respiratory diseases (ARE)
The activity of acute respiratory illness (ARE) is nationwide in the 14th KW 2015 compared to
Previous week declined significantly. The values of the index were practice in the twelve AGI regions in the field of
ARE-background activity (Table 1; Fig. 1.).
...
Reporting data for the Infection Protection Act (IfSG)
Previously were 1,388 laboratory-confirmed clinical influenza cases to the RKI for 14 MW in 2015
Submitted: 358 cases with non subtypisierter influenza A, 34 cases of influenza A (H1N1) pdm09, twelve
Cases of influenza A (H3N2), 34 cases of undifferentiated by influenza A or B and 950 cases with
Influenza B (Tab. 4). In 234 (17%) patients reported that they were hospitalized.
Since 2014, a total of 40 MW 66,256 laboratory-confirmed clinical influenza cases in
RKI transmitted. At 10,421 (16%) cases had indicated that they were hospitalized (data
08.04.2015).

So far, 202 deaths were transmitted with influenza infection at the RKI, including 129 cases with
not subtypisierter influenza A, 28 cases of influenza A (H1N1) pdm09, seven cases of influenza
A (H3N2), 17 cases with no differentiation by influenza A or B, and 16 cases with influenza B. Moreover,
were sent to five clinical-epidemiological confirmed deaths associated with
Influenza outbreaks in nursing homes are.

The different distribution of the identified influenza A subtypes in the AGI-Sentinel and the
Reporting data can be, among other things due to the fact that after the 2009 pandemic, the PCR for subtyping
for influenza A (H1N1) is established pdm09 much wider than for A (H3N2), or integrated in multiplex PCR
has become. The distribution of the circulating in the population influenza types and subtypes is in AGISentinel
therefore better represented.
...

https://influenza.rki.de/Wochenberichte/2014_2015/2015-14.pdf

[Ronan Kelly]

Week 15 (04.04. To 10.04.2015)
Summary evaluation of the epidemiological situation

With influenza-weekly report for the 15th KW winter season ends. The incoming data
From week 16 continued to be assessed weekly and, exceptionally, for the 16 KW another weekly report
published. Subsequently, the reporting in the summer season is monthly.

The activity of acute respiratory illness (ARE) is the nation's 15th calendar week (CW) in 2015
compared to last week remained stable. The values of the index were a total of practice in the field of
ARE-background activity and were in a normal for the season level.
The National Reference Center (NRC) for influenza were in the 15 KW 2015. 21 (53%) of 40
submitted Sentinel samples identified respiratory viruses. In 14 (35%) samples influenza viruses were
demonstrated.
After Infection Protection Act (IfSG) were used for the 15 week reporting (MW) in 2015 so far and since 756
With 40 MW in 2014 were sent to 67,471 laboratory-confirmed clinical influenza cases to the RKI
(Data as of 04.14.2015).
The end of the flu season has not been reached on the definition of AGI, part of the acute respiratory diseases
is not caused by influenza viruses.

Acute respiratory diseases (ARE)
The activity of acute respiratory illness (ARE) is the nation's 15th-KW 2015 compared to
Previous week remained stable and was in the range of background activity. The changes in the values of
Index practice in individual AGI regions compared to last week can probably also on a comparable
be attributed ?ndertes consultation behavior during the Easter period (Table 1; Fig. 1.).
...
Reporting data for the Infection Protection Act (IfSG)
So far been 756 laboratory-confirmed clinical influenza cases to the RKI for 15 MW in 2015
Submitted: 140 cases with non subtypisierter influenza A, 17 cases of influenza A (H1N1) pdm09, six
Cases of influenza A (H3N2), 26 cases of undifferentiated by influenza A or B and 567 cases with
Influenza B (Tab. 4). In 126 (17%) patients reported that they were hospitalized.
Since 2014, a total of 40 MW 67,471 laboratory-confirmed clinical influenza cases in
RKI transmitted. At 10,527 (16%) cases had indicated that they were hospitalized (data
14.04.2015).
So far, 227 deaths were transmitted with influenza infection at the RKI, including 148 cases with
not subtypisierter influenza A, 29 cases of influenza A (H1N1) pdm09, seven cases of influenza
A (H3N2), 19 cases without differentiation by influenza A or B, and 19 cases with influenza B. Moreover,
were sent to five clinical-epidemiological confirmed deaths associated with
Influenza outbreaks in nursing homes are.
The different distribution of the identified influenza A subtypes in the AGI-Sentinel and the
Reporting data can be, among other things due to the fact that after the 2009 pandemic, the PCR for subtyping
for influenza A (H1N1) is established pdm09 much wider than for A (H3N2), or integrated in multiplex PCR
was. The distribution of the circulating in the population influenza types and subtypes is in AGISentinel
therefore better represented.
...

https://influenza.rki.de/Wochenberichte/2014_2015/2015-15.pdf