France - Virus mutation found in two swine flu deaths

[Gert van der Hoek]

google translated

Influenza A: Two cases of mutation in France

Institut de Veille Sanitaire, INVS, said Friday in a statement the "reference
mutations in the genome of influenza virus A (H1N1) "in two deceased patients .

Identical to that reported in Norway, "this change could increase the capacity of the virus
reach the lower respiratory tract, and in particular, to reach the lung tissue, "explains
INVS.

"This is the first resistant strain in France among the 1200 strains analyzed so far.
Investigations will be launched to determine "the impact of these mutations on the
pathogenicity and diffusing capacity of these viruses.

However, the effectiveness of vaccines "is not questioned. Since the epidemic began, 76
people died in metropolitan France.

http://www.lejdd.fr/Societe/Sante/Depeches/Grippe-A-Deux-cas-de-mutation-en-France-153716/

[yielddude]

Re: France - Virus mutation found in two swine flu deaths

UPDATE: Two Die In France After Mutated Swine Flu InfectionLast update: 11/27/2009 11:05:58 AM(Adds quotes) PARIS (AFP)--Two patients who were infected by a A/H1N1 swine flu mutation that was also recently detected in Norway have died in France, health officials said Friday. "This mutation could increase the ability of the virus to affect the respiratory tracts and, in particular, the lung tissue," said a statement from the government's Health Surveillance Institute. "For one of these patients, this mutation was accompanied by another mutation known to confer resistance to oseltamivir," it added, referring to the main drug being used to treat swine flu, under the brand name Tamiflu, which is made by Roche Holding AG (ROG.VX). (END) Dow Jones NewswiresNovember

[Anne]

Re: France - Virus mutation found in two swine flu deaths

http://www.ladepeche.fr/article/2009...a-Gironde.html

detail :
these two people had no relationship and were hospitalized in two different cities.

2 mutations in one patient :
tamiflu resistance and 222 ( like " norway )

[Treyfish]

Re: France - Virus mutation found in two swine flu deaths

Influenza A new mutation of the virus
After the three cases emerged in Norway, two other scoeprti today in France

Two French patients who died after being infected by influenza A H1N1 has been detected the presence of a mutation of the virus. This was announced the National Institute for health monitoring that this is a phenomenon similar to what has been observed in three cases in Norway.

According to the French health authorities, "they are two patients without any mutual bonds, admitted to different health facilities, and that situation should not be underestimated, which could lead to increased aggressiveness of the virus in particular the lung tissue.

"Further investigations are needed on this mutation of the virus to determine whether the sign of a change from a clinical or epidemiological point of view, we do not know. Mutations of the viruses are common and are not necessarily important, "he said in recent days in Geneva, a senior World Health Organizationhttp://info.rsi.ch/home/channels/inf...one-virus.html

[Celvin11]

Re: France - Virus mutation found in two swine flu deaths

More to topic :

Le Monde :Deux patients porteurs d'une mutation du virus A(H1N1) sont morts

http://www.lemonde.fr/epidemie-grippe-a/article/2009/11/27/deux-patients-porteurs-d-une-mutation-du-virus-a-h1n1-sont-morts_1273200_1225408.html

Dagbladet : Mutert svinevirus fra Norge har tatt to franske liv

http://www.dagbladet.no/2009/11/27/nyheter/svineinfluensa/utenriks/pandemi/frankrike/9233682/