Swine Influenza: Danish is resistant to Tamiflu
Statens Serum Institut have found the first person in the world who are resistant to the medication oseltamivir, sold under the name Tamiflu, and among others have proven company against swine flu H1N1.
It is the first case of resistance to the drug worldwide. It is expected that influenza virus can mutate spontaneously. Resistance has not changed the H1N1 virus' ability to infect or cause disease, shall instuttet.
- Both bacteria and viruses can mutate and become resistant. And that is what has happened here, confirms CEO at Statens Serum Institut Nils Strandberg.
- He had to start with no ill. That was in the preventive treatment with Tamiflu, because he had been in close contact with a swine influenza hit abroad. Since there had been five days of Tamiflu, the person suddenly ill with H1N1, but it not appear that the medicine worked. It appeared as through the samples here and in England that the person had been resistance, "says Nils Strandberg.
Disadvantageous for the seriously ill
Instead, the patient was treated with medication Relenza.
- We can rejoice that the person is today is quite healthy and has not infected others, says Nils Stand Berg.
- But there is surely bleak prospects that Tamiflu will no longer be regarded as a safe weapon against swine flu?
- Yes, it is worrying if Tamiflu does not work on the most vulnerable groups. But there is still something to do if a sickly patient become infected with H1N1. There is another substance that can be used.
Turn down the preventive use
According to Nils Strandberg would find the resistant Dane mean that doctors will be more reluctant to use preventive Tamiflu - unless there actually are very sick and frail patients.
- Why is it just a Dane who is the first resistant influenza patient?
- It probably depends most on a case. We have a good system where we are good to monitor the situation.
The incident confirms that influenza virus can mutate and that Tamiflu can not be regarded as miracle drugs. Tamiflu is already not cure flu, but the medication can reduce symptoms and shorten the process.
Epidemic in the autumn
Even in summer, outdoor life and the closed schools will mean less flu infection in Denmark, the Danes will travel over the summer mean that there will be dragged more infections in the country.
- We should probably until the late autumn or winter before we can risk a H1N1 epidemic at home. But it need not cause problems, since it is still a relatively mild influenza, "says Nils Stand Berg.