Russia - 1 outbreak of highly pathogenic avian influenza H5N1 in Dalmatian pelican in Astrakhanskaya Oblast (OIE, April 27, 2015)

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Highly pathogenic avian influenza, Russia

Information received on 27/04/2015 from Dr Evgeny Nepoklonov, Deputy Head, Federal Service for Veterinary and Phytosanitary Surveillance, Ministry of Agriculture, Moscow, Russia

Summary Report type Immediate notification (Final report) Date of start of the event 17/04/2015 Date of confirmation of the event 21/04/2015 Report date 27/04/2015 Date submitted to OIE 27/04/2015 Date event resolved 27/04/2015 Reason for notification Reoccurrence of a listed disease Date of previous occurrence 10/2014 Manifestation of disease Sub-clinical infection Causal agent Highly pathogenic avian influenza virus Serotype H5N1 Nature of diagnosis Laboratory (basic), Laboratory (advanced) This event pertains to a defined zone within the country

New outbreaks (1)

Outbreak 1 Makarkin, Ikryaninsky, ASTRAKHANSKAYA OBLAST Date of start of the outbreak 17/04/2015 Outbreak status Resolved (27/04/2015) Epidemiological unit Not applicable Affected animals Species Susceptible Cases Deaths Destroyed Slaughtered Dalmatian pelican:Pelecanus crispus(Pelecanidae) 5 5 0 0 Affected population The dead water birds were found in the Damchinsky area of the FGBI (Federal Centre for Animal Health) Astrakhan State Biosphere Reserve.

Summary of outbreaks Total outbreaks: 1 Total animals affected Species Susceptible Cases Deaths Destroyed Slaughtered Dalmatian pelican:Pelecanus crispus(Pelecanidae) 5 5 0 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Dalmatian pelican:Pelecanus crispus(Pelecanidae) ** ** 100.00% ** *Removed from the susceptible population through death, destruction and/or slaughter **Not calculated because of missing information

Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments The comparative analysis of the obtained nucleotide sequences of the H gene 258 bp fragment showed that the tested isolates belonged to an Asian lineage of highly pathogenic avian influenza (lineage A/Guandong/1/96 lineage, clade 2.3.2.1). Based on the H gene fragment nucleotide sequences the given isolates were the most similar to type A H5N1 highly pathogenic avian influenza virus isolates recovered in Altay krai in 2014 (98.83 % identity) and in Vietnam and China over the period from 2012 to 2014 (98.44-98.04% identity). The hemagglutinin cleavage site of this virus includes several basic amino acids and has -RERRRKR- structure which allows this virus to be characterized as potentially highly virulent.

Control measures Measures applied Control of wildlife reservoirs Screening No vaccination No treatment of affected animals Measures to be applied No other measures

Diagnostic test results Laboratory name and type Species Test Test date Result Government Budget Institution Astrakhan Oblast Veterinary Laboratory (Local laboratory) Dalmatian pelican polymerase chain reaction (PCR) 21/04/2015 Positive All-Russian Research Institute for Animal Health (FGBI-ARRIAH) (National laboratory) Dalmatian pelican gene sequencing 24/04/2015 Positive All-Russian Research Institute for Animal Health (FGBI-ARRIAH) (National laboratory) Dalmatian pelican haemagglutination inhibition test (HIT) 24/04/2015 Positive All-Russian Research Institute for Animal Health (FGBI-ARRIAH) (National laboratory) Dalmatian pelican real-time reverse transcriptase/polymerase chain reaction (RRT-PCR) 24/04/2015 Positive All-Russian Research Institute for Animal Health (FGBI-ARRIAH) (National laboratory) Dalmatian pelican virus isolation 24/04/2015 Positive

Future Reporting The event is resolved. No more reports will be submitted.

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