UK - British nurse Pauline Cafferkey who recovered from Ebola back in hospital again - discharged

[Pathfinder]

Life | Tue Feb 23, 2016 5:14am EST Related: HEALTH

British nurse who recovered from Ebola back in hospital again

LONDON

A Scottish nurse, who recovered from Ebola but then suffered life-threatening complications from the virus persisting in her brain, has been admitted to hospital for a third time, a hospital in Scotland said on Tuesday.

Pauline Cafferkey contracted Ebola in December 2014 when she was working in a treatment facility in Sierra Leone at the height of an epidemic of the disease which swept through three countries in West Africa.

Cafferkey is now at the Queen Elizabeth University Hospital in Glasgow, Scotland's biggest city.
...

http://www.reuters.com/article/us-health-ebola-britain-nurse-idUSKCN0VW0W2

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Statement re Pauline Cafferkey

Tuesday, February 23, 2016

Under routine monitoring by the Infectious Diseases Unit Pauline Cafferkey has been admitted to hospital for further investigations.

To protect patient confidentiality, we will not be publishing regular updates on this patient?s condition.

http://www.nhsggc.org.uk/about-us/media-centre/news/2016/02/statement-re-pauline-cafferkey/

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Updated Pauline Cafferkey statement

Tuesday, February 23, 2016

Ms Cafferkey was admitted to the Queen Elizabeth University Hospital under routine monitoring by the Infectious Diseases Unit.

She is undergoing further investigations and her condition remains stable.

http://www.nhsggc.org.uk/about-us/media-centre/news/2016/02/updated-pauline-cafferkey-statement/

[FrenchieGirl]

Nurse Cafferkey is being air-lifted to London at the Royal Free Hospital

http://news.stv.tv/west-central/1343843-scots-ebola-nurse-pauline-cafferkey-back-in-hospital/

[Pathfinder]

Pauline Cafferkey transferred to RFH

23 February 2016

We can confirm that Pauline Cafferkey is being transferred to the Royal Free Hospital due to a late complication from her previous infection by the Ebola virus. She will now be treated by the hospital's infectious diseases team under nationally agreed guidelines.

The Ebola virus can only be transmitted by direct contact with the blood or bodily fluids of an infected person while they are symptomatic so the risk to the general public remains low and the NHS has well established and practised infection control procedures in place.

ENDS

https://www.royalfree.nhs.uk/news-media/news/pauline-cafferkey-transferred-to-rfh-1/

[Emily]

Treatment history:

https://www.highbeam.com/doc/1P2-37610108.html

Doctor : Experimental Drug Was Tried on Pauline, but Medic Says in the End She Probably Cured Herself Scotland on Sunday (Edinburgh, Scotland)
January 25, 2015 | Christie, Kevan
...
Dr Michael Jacobs, the head of the infectious diseases unit at the Royal Free Hospital in London who was in charge of the Scottish nurse's intensive care, said he obtained a supply of ZMabb after clinical discussions with his Canadian counterparts.The experimental drug was used in place of ZMapp, which has already been used on Ebola patients, after it emerged there are currently no supplies available...

ZMab is the correct spelling. This was the non-optimized cocktail, part of which was later incorporated into Zmapp.

Nurse Cafferkey may be the only Ebola survivor to have received ZMab:

http://www.cp24.com/news/canada-gives-spain-norway-experimental-drug-to-treat-ebola-cases-1.2054145

Helen Branswell, The Canadian Press
Published Wednesday, October 15, 2014 7:54AM EDT
Canada gives Spain, Norway experimental drug to treat Ebola cases
TORONTO -- The Public Health Agency of Canada gave health officials in Spain and Norway a ZMapp-like drug to treat two health-care workers infected with Ebola, the agency confirmed Tuesday. The National Microbiology Laboratory in Winnipeg sent Spain and Norway one treatment course each of ZMab, a monoclonal antibody cocktail developed at the lab.
The supplies of the drug were what is called laboratory grade and had been made for research in animals. Drugs used in humans are made to the rigorous standards known as current good manufacturing practices or cGMP.
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It is not clear whether either health-care worker has received the treatment.
Media reports from Spain have presented a conflicting picture about whether the woman there actually received the drug. A Spanish news website, Lainformacion.com, quoted Fernando Simon, head of Spain's Centre for Health and Emergency Alerts, as saying ZMab was not given to the woman because of concerns over possible side-effects....

https://flutrackers.com/forum/forum/europe/ebola-tracking-england/739536-united-kingdom-scottish-nurse-treated-for-ebola-complication-full-recovery-from-ebola-discharged?p=739983#post739983

One possibility is that late complications could be an unanticipated consequence of experimental treatments that include antibodies, like ZMapp, that help remove the virus from the patient’s blood, but are not thought to be capable of crossing from the bloodstream into the brain.
By decreasing the amount of virus in the blood, “you perhaps blunt the immune system,” Dr. Bausch said. “It’s all speculation, but it’s scientifically sound speculation.”

[Pathfinder]

Pauline Cafferkey discharged

28 February 2016

Pauline Cafferkey has today (Sunday 28 February) been discharged from the care of the Royal Free Hospital following her admission due to a complication related to her previous infection by the Ebola virus.

We can confirm that Pauline is not infectious. The Ebola virus can only be transmitted by direct contact with the blood or bodily fluids of an infected person while they are symptomatic.
...

http://www.royalfree.nhs.uk/news-media/news/pauline-cafferkey-discharged-1/