Russian Lymphoma Patient Acquired 18 COVID-19 Mutations in Months-Long Disease, Study Finds
10:08 GMT 12.01.2021Get short URL

MOSCOW (Sputnik) - A Russian lymphoma patient with long-term COVID-19 has acquired 18 mutations of the virus in over four months duration of the disease, according to the preprint of a study published at

The study, released in early January, is authored by researchers from the Skolkovo Institute of Science and Technology, the Institute for Information Transmission Problems of the Russian Academy of Sciences, Pavlov First State Medical University of St. Petersburg, Smorodintsev Research Institute of Influenza, and a St. Petersburg city hospital.

"We report a genomic analysis of SARS-CoV-2 from a lymphoma patient with long-term COVID-19. This genome is characterized by an independent gain of 18 new mutations over more than 4 months of the disease. These include the S:Y453F and Δ69-70HV mutations (‘the ΔF combination’) which have formerly been associated with mink-related clusters," the preprint read.

The mutations developed in a 47-year-old female lymphoma patient, who goes by Patient S in the study. Patient S likely contracted the virus when she was on planned chemotherapy in a hospital...