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New Orthobunyavirus of the Simbu serogroup discovered in cattle in Switzerland and Germany

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  • New Orthobunyavirus of the Simbu serogroup discovered in cattle in Switzerland and Germany

    Translation Google

    A disease of unknown origin is spreading among dairy cows

    AFP

    Reports of fever, diarrhea and a marked drop in milk production are multiplying in Swiss farms, without the cause of this disease yet being known, federal authorities indicated on Wednesday.

    Updated: 01.08.2026 07:23

    The Federal Office for Food Safety and Veterinary Affairs (Focus) " is aware of reports of an increase in cases of disease in dairy cows ".

    " Several animal owners are reporting fever and diarrhea, often accompanied by a marked drop in milk production," but "the cause has not yet been identified ," he said in a statement.

    Investigations are underway to examine "both metabolic and possible infectious causes".

    " To date, no pathogen has been identified as an infectious cause " and "no direct link between the current heat wave and the reported cases of diarrhea has been established ," the Osav stated.

    But he points out that " high temperatures nevertheless represent a significant burden, particularly for high-yield dairy cows, and can make them more vulnerable to disease ."

    Like other European countries, Switzerland has been experiencing repeated heat waves in recent weeks, accompanied by a significant rainfall deficit.

    The Osav reminds us that during periods of high heat, animals must be systematically protected against heat stress, in particular by ensuring they have enough water, shaded areas and appropriate cooling measures.

    Furthermore, he points out that non-specific symptoms such as fever, diarrhea or a drop in milk production " can also be a sign of a highly contagious epizootic" .

    Therefore, the Osav calls on animal owners to " immediately inform their veterinarian so that the necessary examinations can be carried out, if necessary ".

    Les signalements de fièvre, de diarrhée et de chute marquée de la production laitière se multiplient dans les élevages suisses, sans que la cause de cette maladie soit encore connue, ont indiqué mercredi les autorités fédérales.


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    Information published on July 31, 2026

    Diseases in dairy cows: the FSVO is monitoring the situation

    Reports of fever, diarrhea, and sharp drops in milk production are increasing among dairy cows. Investigations involve veterinarians, industry representatives, universities, laboratories, and veterinary authorities.

    The Federal Food Safety and Veterinary Office (FSVO) is aware of reports of an increase in cases of illness among dairy cows. Several animal owners are reporting fever and diarrhea, often accompanied by a significant drop in milk production. The cause has not yet been identified. Investigations are underway to examine both metabolic and potential infectious causes. These investigations are being conducted in collaboration with practicing veterinarians, Swiss Cattle Health, veterinary medicine faculties and laboratories, as well as veterinary authorities.

    To date, no pathogen has been identified as the infectious cause. No direct link between the current heat wave and the reported cases of diarrhea has been established. However, high temperatures represent a significant burden, particularly for high-producing dairy cows, and can make them more susceptible to disease.

    During periods of intense heat, animals must therefore be systematically protected against heat stress, in particular by ensuring they have sufficient water, shaded areas and appropriate cooling measures.

    Nonspecific symptoms such as fever, diarrhea, or decreased performance can also be signs of a highly contagious epizootic disease. Pet owners should therefore inform their veterinarian immediately so that any necessary tests can be carried out.

    The Federal Food Safety and Veterinary Office (FSVO) is monitoring the situation with the relevant specialist services and is constantly reassessing it. If further measures become necessary, they will be considered.

    https://www.blv.admin.ch/fr/maladies...uit-levolution

    ​​

  • #2
    Source: https://www.cp24.com/news/world/2026...stery-illness/

    Swiss cows struck by mystery illness
    By AFP
    Published: August 03, 2026 at 3:23PM EDT​

    GENEVA - A virus spread by biting midges never before seen in Switzerland is thought to be responsible for a surge in sickness in Swiss dairy cows, authorities said Monday.

    Several regions of the Alpine country have recorded a spike in illnesses since mid-July, with cows suffering from fever and diarrhoea and producing less milk, the Federal Food Safety and Veterinary Office (FSVO) said.

    “Investigations by the Institute of Virology and Immunology (IVI) have detected an orthobunyavirus of the Simbu group in several acutely ill animals -- a virus previously unknown in Switzerland,” the FSVO said.

    Genetic testing is under way to determine the exact orthobunyavirus and whether it is the cause of the observed illnesses, the office added.

    Orthobunyaviruses of the Simbu group are primarily transmitted by biting midges, and no vaccines are currently available, the FSVO said.

    The IVI said its preliminary findings align with evidence from France and Germany, “where the suspicion that an orthobunyavirus is circulating... is also gaining traction.”​...

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    • #3
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      Translation Google

      Published on August 3, 2026

      New Orthobunyavirus of the Simbu serogroup discovered in cattle

      The IVI has detected an orthobunyavirus from the Simbu serogroup, related to the Schmallenberg virus, in samples from cattle exhibiting fever, diarrhea, and reduced milk production. This strengthens the evidence for the first occurrence of another virus from this group in Switzerland since the initial Schmallenberg virus outbreak in 2012.

      The IVI's preliminary findings align with evidence from France and Germany, where the suspicion that an orthobunyavirus of the Simbu serogroup is circulating is also gaining traction. Initial characterizations using next-generation sequencing (NGS) at the FLI show a high degree of relatedness to the Shamonda virus. Viruses of the Simbu serogroup, which also includes the Schmallenberg virus, are found primarily in Africa, Asia, and Australia and, similar to the bluetongue virus, are transmitted by blood-sucking midges of the genus Culicoides.

      It is currently unclear whether there is a connection between the current heat wave and the reported cases of illness. However, high temperatures pose a significant stress, especially for high-yielding dairy cows, and can make the animals more susceptible to disease.

      Observed clinical symptoms:

      Nearly all affected cattle farms report a disease event lasting approximately 14–21 days . The most common clinical symptoms are:
      • Fever (>40 °C) lasting 1–2 days
      • Massive decline in milk supply
      • Loss of appetite
      • Diarrhea
      Sample material to be submitted
      • Viral genome detection (RT-qPCR) of newly ill, febrile animals:
        - Live animal: EDTA blood or serum
        - Dead animal: brain, spleen, body cavity fluid
      • Antibody detection (ELISA)
        - Live animal: Serum
        - Dead animal: Body cavity fluid
      ...

      Das IVI hat in Proben von Rindern mit Fieber, Durchfall und Milchrückgang ein dem Schmallenberg-Virus verwandtes Orthobunyavirus aus der Simbu-Serogruppe nachgewiesen. Damit verdichten sich die Hinweise auf das erstmalige Auftreten eines weiteren Virus dieser Gruppe in der Schweiz seit dem ersten Ausbruch des Schmallenberg-Virus im Jahr 2012.

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      FLI detects a new orthobunyavirus of the Simbu serogroup (“Shamonda-like”) in cattle in Germany


      08/03/2026

      Press Releases

      The Friedrich-Loeffler-Institut (FLI) has detected a previously uncharacterised orthobunyavirus of the Simbu serogroup in samples from affected cattle in southern Germany. Following the first appearance of the Schmallenberg virus in 2011, this once again provides reliable evidence that a new virus from this group has been introduced into Germany. The newly detected virus shows the closest relationship to the Shamonda virus in all three segments. Viruses of the Simbu serogroup are found primarily in Africa, Asia and Australia. Like bluetongue virus and Schmallenberg virus, they are transmitted by blood-sucking midges of the genus Culicoides. The animals most commonly infected are ruminants, particularly cattle, sheep and goats.

      Cases were first detected in cattle in Switzerland, France and southern Germany, particularly in Baden-Württemberg. The affected animals showed signs of fever and diarrhoea. In dairy cows, a decline in milk yield – in some cases significant – was also observed. These clinical signs have been observed in numerous animals and herds since July. The clinical signs were initially consistent with infection by the Schmallenberg virus. However, tests for Schmallenberg virus, as well as for other known pathogens such as bluetongue virus or epizootic haemorrhagic disease virus, proved negative.

      Samples from four affected cattle herds were submitted to the FLI by the local state veterinary laboratory (Chemisches und Veterinäruntersuchungsamt Freiburg). Within 48 hours, the samples had been analysed and the pathogen further characterised. A Pan-Simbuvirus PCR revealed clear positive signals in several serum and blood samples from different farms, with Ct values of up to around 20. This indicates high viral loads at the time of sampling. Further PCR tests for viruses in this group also yielded positive results.

      Whole-genome sequencing revealed that all three genome segments showed the highest sequence similarity to Shamonda viruses (at the amino acid level: S: 99 %; M: 95 %; L: 97 %). Whilst the S and L segments are also closely related to Schmallenberg virus, the M segment – which is particularly relevant for antigenicity and the immune response – shows a significantly lower degree of similarity (<50 %). The final taxonomic classification of the virus is currently pending.

      Infections with viruses of the Simbu serogroup generally lead to a brief period of viraemia and only mild to moderate clinical signs in adult animals. Of particular significance, however, is the potential transmission to the foetus during pregnancy. Depending on the timing of the infection, abortions, stillbirths and severe congenital malformations may occur. In the case of e Schmallenberg virus, sheep were particularly affected by this. In some flocks, malformation was observed in up to 50 % of the offspring. In cattle, foetal malformations were less pronounced.

      As regards the newly identified ‘Shamonda-like’ virus, it is not yet possible to assess whether, and to what extent, infections in pregnant animals may lead to malformation in the foetuses. Abortions, stillbirths and malformed calves or lambs from herds that may be affected should therefore be examined.

      Depending on the weather, the midge season in Germany lasts until around the end of November. Midge activity is usually at its peak between July and October. Given the generally efficient transmission by midges, a further and potentially rapid spread of the virus within susceptible herds is therefore anticipated.

      Viruses of the Simbu serogroup are not generally considered to be zoonotic agents and, based on current knowledge, do not pose a significant risk of infection to humans. However, in the case of newly emerging and insufficiently characterised viruses in this group, their potential zoonotic risk should be investigated as a precautionary measure and closely monitored as the situation develops.

      The FLI is giving high priority to the complete characterisation of the pathogen, the epidemiological tracing of cases, and the adaptation and development of specific diagnostic methods. “Following the 2011 Schmallenberg virus outbreak, an exotic orthobunyavirus has once again been introduced into Central Europe. Investigations over the coming weeks will reveal how rapidly it is spreading, which animal species are particularly affected, and what clinical consequences can be expected. Of crucial importance is the question of whether infections during pregnancy lead to foetal malformation,” said Prof. Dr. Martin Beer, Vice-President of the Friedrich-Loeffler-Institut. In principle, vaccines can be developed against orthobunyaviruses. However, this requires sufficient lead time. The necessity and urgency of vaccine development will depend largely on the clinical and, in particular, reproductive significance of the newly introduced virus.

      Database access to sequence information on the new ‘Shamonda-like virus’:
      ASSEMBLY_NAME | ASSEMBLY_ACC | STUDY_ID | SAMPLE_ID | CONTIG_ACC | SCAFFOLD_ACC | CHROMOSOME_ACC amp07736 | GCA_987215895 | PRJEB123174 | ERS31023854 | | | OZ502471-OZ502473


      Cattle family (© FLI )

      For downloadhttps://www.fli.de/en/press/press-re...le-in-germany/

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