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Reduction of Coxiella burnetii Prevalence by Vaccination of Goats and Sheep, the Netherlands

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  • Reduction of Coxiella burnetii Prevalence by Vaccination of Goats and Sheep, the Netherlands

    Excerpt from study

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    Reduction of Coxiella burnetii Prevalence by Vaccination of Goats and Sheep, the Netherlands


    Recently, the number of human Q fever cases in the Netherlands increased dramatically. In response to
    this increase, dairy goats and dairy sheep were vaccinated against Coxiella burnetii.

    All pregnant dairy
    goats and dairy sheep in herds positive for Q fever were culled. We identified the effect of vaccination on
    bacterial shedding by small ruminants. On the day of culling, samples of uterine fluid, vaginal mucus, and
    milk were obtained from 1,034 pregnant animals in 13 herds.

    Prevalence and bacterial load were reduced
    in vaccinated animals compared with unvaccinated animals. These effects were most pronounced in
    animals during their first pregnancy.

    Results indicate that vaccination may reduce bacterial load in the
    environment and human exposure to C. burnetii.
    “Addressing chronic disease is an issue of human rights – that must be our call to arms"
    Richard Horton, Editor-in-Chief The Lancet

    ~~~~ Twitter:@GertvanderHoek ~~~ GertvanderHoek@gmail.com ~~~
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