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Source: http://hhv-6foundation.org/miscarria...to-infertility
HHV-6A infection of the uterus linked to infertility
July 7, 2016A new study published in PLOS Pathogens found that HHV-6A is implicated in female infertility. Italian researchers have found HHV-6A in the uterine biopsies of 43% of women with unexplained infertility compared to 0% of controls. Furthermore, the cytokine and the natural killer cell profiles were very different in patients with the infection. HHV-6A was found only in uterine endothelial cells, and not in the blood, whereas latent HHV-6B was found in equal amounts in the blood of both patients and controls.
A team led by Roberta Rizzo, Roberto Marci, and Dario DiLuca of the University of Ferrara tested endometrial biopsies from 30 women with unexplained primary infertility as well as 36 fertile women. HHV-6 DNA was found in the endometrial samples from 13 of 30 infertile women (43%), but none among the fertile women. Surprisingly, all of the virus was HHV-6A, not HHV-6B, the virus that reactivates in immunocompromised patients and causes roseola in infants. Over 97% of HHV-6 reactivation in transplant patients is typed as HHV-6B...
HHV-6A infection of the uterus linked to infertility
July 7, 2016A new study published in PLOS Pathogens found that HHV-6A is implicated in female infertility. Italian researchers have found HHV-6A in the uterine biopsies of 43% of women with unexplained infertility compared to 0% of controls. Furthermore, the cytokine and the natural killer cell profiles were very different in patients with the infection. HHV-6A was found only in uterine endothelial cells, and not in the blood, whereas latent HHV-6B was found in equal amounts in the blood of both patients and controls.
A team led by Roberta Rizzo, Roberto Marci, and Dario DiLuca of the University of Ferrara tested endometrial biopsies from 30 women with unexplained primary infertility as well as 36 fertile women. HHV-6 DNA was found in the endometrial samples from 13 of 30 infertile women (43%), but none among the fertile women. Surprisingly, all of the virus was HHV-6A, not HHV-6B, the virus that reactivates in immunocompromised patients and causes roseola in infants. Over 97% of HHV-6 reactivation in transplant patients is typed as HHV-6B...