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Emerg Infect Dis. Novel Arenavirus Infection in Humans, United States
[Source: Emerging Infectious Diseases Journal, full text: (LINK). Abstract, edited.]
DOI: 10.3201/eid1708.110285
Suggested citation for this article: Milazzo ML, Campbell GL, Fulhorst CF. Novel arenavirus infection in humans, United States. Emerg Infect Dis. 2011 Aug; [Epub ahead of print]
Novel Arenavirus Infection in Humans, United States
Mary Louise Milazzo, Grant L. Campbell, and Charles F. Fulhorst
Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA (M.L. Milazzo, C.F. Fulhorst); and Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (G.L. Campbell)
Immunoglobulin G against Whitewater Arroyo virus or lymphocytic choriomeningitis virus was found in 41 (3.5%) of 1,185 persons in the United States who had acute central nervous system disease or undifferentiated febrile illnesses. The results of analyses of antibody titers in paired serum samples suggest that a North American Tacaribe serocomplex virus was the causative agent of the illnesses in 2 persons and that lymphocytic choriomeningitis virus was the causative agent of the illnesses in 3 other antibody-positive persons in this study. The results of this study suggest that Tacaribe serocomplex viruses native to North America, as well as lymphocytic choriomeningitis virus, are causative agents of human disease in the United States.
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DOI: 10.3201/eid1708.110285
Suggested citation for this article: Milazzo ML, Campbell GL, Fulhorst CF. Novel arenavirus infection in humans, United States. Emerg Infect Dis. 2011 Aug; [Epub ahead of print]
Novel Arenavirus Infection in Humans, United States
Mary Louise Milazzo, Grant L. Campbell, and Charles F. Fulhorst
Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA (M.L. Milazzo, C.F. Fulhorst); and Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (G.L. Campbell)
Immunoglobulin G against Whitewater Arroyo virus or lymphocytic choriomeningitis virus was found in 41 (3.5%) of 1,185 persons in the United States who had acute central nervous system disease or undifferentiated febrile illnesses. The results of analyses of antibody titers in paired serum samples suggest that a North American Tacaribe serocomplex virus was the causative agent of the illnesses in 2 persons and that lymphocytic choriomeningitis virus was the causative agent of the illnesses in 3 other antibody-positive persons in this study. The results of this study suggest that Tacaribe serocomplex viruses native to North America, as well as lymphocytic choriomeningitis virus, are causative agents of human disease in the United States.
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