Announcement

Collapse
No announcement yet.

Science. Island Biogeography Reveals the Deep History of SIV

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Science. Island Biogeography Reveals the Deep History of SIV

    Island Biogeography Reveals the Deep History of SIV (Science, abstract, edited)


    [Source: Science, free abstract: <cite cite="http://www.sciencemag.org/cgi/content/abstract/329/5998/1487">Island Biogeography Reveals the Deep History of SIV -- Worobey et al. 329 (5998): 1487 -- Science</cite>. Edited.]

    Science 17 September 2010: Vol. 329. no. 5998, p. 1487
    DOI: 10.1126/science.1193550

    Island Biogeography Reveals the Deep History of SIV

    Michael Worobey,1 Paul Telfer,2,3 Sandrine Souqui?re,3 Meredith Hunter,2 Clint A. Coleman,2 Michael J. Metzger,2 Patricia Reed,2,3 Maria Makuwa,3 Gail Hearn,4 Shaya Honarvar,4 Pierre Roques,3 Cristian Apetrei,2 Mirdad Kazanji,3 Preston A. Marx2,*


    Simian immunodeficiency virus (SIV) lineages have been identified that are endemic to Bioko Island. The time the island formed offers a geological time scale calibration point for dating the most recent common ancestor of SIV. The Bioko viruses cover the whole range of SIV genetic diversity, and each Bioko SIV clade is most closely related to viruses circulating in hosts of the same genus on the African mainland rather than to SIVs of other Bioko species. Our phylogeographic approach establishes that SIV is ancient and at least 32,000 years old. Our conservative calibration point and analyses of gene sequence saturation and dating bias suggest it may be much older.

    1 University of Arizona, Tucson, AZ 85721, USA.
    2 Tulane National Primate Research Center, Covington, LA 70433, USA.
    3 Center for International Medical Research, Franceville, Gabon.
    4 Drexel University, Philadelphia, PA 19104, USA.
    * To whom correspondence should be addressed. E-mail: pmarx@tulane.edu
    -
    ------
Working...
X