Seven children died in Indonesia of new liver disease seen across world

[Shiloh]

Source: https://www.smh.com.au/world/asia/th...02-p5ahvr.html

Three children died in Indonesia of new liver disease seen across world
By Yudith Ho
May 2, 2022 — 4.59pm

Jakarta: Three children in Indonesia died from acute hepatitis in April, the country’s health ministry said, boosting the global death toll from the mysterious liver ailment affecting children from the US to Asia to at least four.

The children, hospitalised in the capital Jakarta, had symptoms including nausea, vomiting, heavy diarrhoea, fever, jaundice, seizures and loss of consciousness, the ministry said in a statement on Monday. It is urging parents to immediately bring children who exhibit these symptoms to the hospital.

The ministry is running a full panel of tests to determine the cause of the disease and has issued a circular to step up nationwide surveillance for the illness, it said...

[alert]

Has Hepatitis A or E or leptospirosis been ruled out here? Those are exclusion diagnoses for the unexplained syndrome and are endemic here. The suspected global death toll for the unexplained disease outbreak is one, so to report three times that in this one city is suspect.

[sharon sanders]

Please see:

Singapore: 10-month-old boy found to have acute hepatitis with unknown cause; MOH investigating

U.S., U.K. investigating unusual cases of hepatitis in young children - April 15, 2022

MMWR - Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022

Japan - Ministry of Health, Labor and Welfare statement: 2 possible cases of acute hepatitis of unknown cause in a child - April 25, 2022+

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Translation Google


The public to be vigilant after 3 pediatric patients with acute hepatitis died

by Rokom
01 May 2022
Reading Time: 3 mins read

Jakarta, May 1, 2022

The Ministry of Health has increased its vigilance in the last two weeks after the World Health Organization (WHO) declared an Extraordinary Event (KLB) in cases of Acute Hepatitis that attacks children in Europe, America and Asia, and the cause has not been known since April 15, 2022.

This vigilance increased after three pediatric patients who were treated at the Dr. Ciptomangunkusumo Jakarta with suspected acute hepatitis whose cause has not yet been determined, died in a different time period from the last two weeks to April 30, 2022.

These three patients are referrals from hospitals in East Jakarta and West Jakarta.

Symptoms found in these patients are nausea, vomiting, severe diarrhea, fever, jaundice, convulsions and decreased consciousness.

Currently, the Indonesian Ministry of Health is trying to investigate the causes of acute hepatitis through a complete virus panel examination. The DKI Jakarta Provincial Health Office is conducting further epidemiological investigations.

“During the investigation period, we urge the public to be careful and remain calm. Take preventive measures such as washing hands, ensuring food is cooked and clean, not changing eating utensils, avoiding contact with sick people and continuing to implement health protocols," said Ministry of Health spokesman dr. Siti Nadia Tarmizi, M. Epid

If children have symptoms of jaundice, abdominal pain, sudden vomiting and diarrhea, old tea-colored urine, pale stools, seizures, decreased consciousness, they should immediately check the child to the nearest health service facility, said dr. Nadia.

Since it was officially published as an outbreak by WHO, the number of reports has continued to grow, with more than 170 cases reported by more than 12 countries.

WHO first received a report on 5 April 2022 from the United Kingdom regarding 10 cases of Acute Hepatitis of Unknown aetiology in children aged 11 months-5 years in the period January to March 2022 in Central Scotland.

The range of cases occurred in children aged 1 month to 16 years. Seventeen of them (10%) required liver transplantation, and 1 case was reported to have died. Clinical symptoms in the identified cases were acute hepatitis with elevated liver enzymes, acute jaundice (jaundice) syndrome, and gastrointestinal symptoms (abdominal pain, diarrhea and vomiting). In most cases, there are no symptoms of fever.

The cause of the disease is still unknown. Laboratory tests abroad have been carried out and hepatitis A, B, C, D and E viruses were not found to be the cause of the disease. Adenovirus was detected in 74 cases abroad which after molecular tests were identified as F type 41. SARS-CoV-2 was found in 20 cases, while 19 cases detected co-infection of SARS-CoV-2 and adenovirus.

The Ministry of Health through the Director General of Disease Prevention and Control issued Circular Letter Number HK.02.02 /C/2515/2022 Concerning Precautions for Finding Cases of Acute Hepatitis of Unknown Aetiology dated April 27, 2022.

ACUTE HEPATITIS OF UNKNOWN AETIOLOGY + Appendix

The Circular is intended to increase the support of the Regional Government, health service facilities, the Port Health Office, health human resources (HR), and stakeholders related to early vigilance of the discovery of cases of Acute Hepatitis of Unknown Etiology.

The Ministry of Health asked the Provincial and District/City Health Offices, Port Health Offices, Public Health Laboratories and Hospitals to, among other things, monitor and report cases of acute jaundice syndrome in the Early Alert and Response System (SKDR), with symptoms marked by discolored skin and sclera. Jaundice or yellow and dark urine that appears suddenly and provides Communication, Information and Education (IEC) to the community as well as prevention efforts through the implementation of Clean and Healthy Living Behavior.

The Ministry of Health also asks related parties to inform the public to immediately visit the nearest Health Service Facility (Fasyankes) if they have Yellow Disease syndrome, and build and strengthen surveillance networks across programs and sectors.

"Of course we are strengthening surveillance through cross-programs and cross-sectors, so that immediate action can be taken if cases of acute jaundice syndrome are found or those with symptoms such as hepatitis symptoms," said dr. Nadia.

The Health Office, KKP, and Hospitals are also asked to immediately provide notification/report if there is an increase in cases of acute jaundice syndrome or find cases according to operational definitions to the Director General of P2P through the Public Health Emergency Operation Center (PHEOC) via Tel./ WhatsApp 0877-7759- 1097 or e-mail: poskoklb@yahoo.com.

This news was broadcast by the Bureau of Communications and Public Services, Ministry of Health of the Republic of Indonesia. For further information, please contact the Halo Ministry of Health hotline number via hotline 1500-567, SMS 081281562620, facsimile (021) 5223002, 52921669, and email address contact@kemkes.go.id (NI)

Head of the Bureau of Communication and Public Services,
drg. Widyawati, MKM

https://sehatnegeriku.kemkes.go.id/baca/rilis-media/20220501/3939769/masyarakat-agar-waspada-setelah-3-pasien-anak-dengan-hepatitis-akut-meninggal-dunia/

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Translation Google

Government Conducts Contact Investigation of 3 Cases of Acute Hepatitis in Children

Published On : Thursday, 05 May 2022 00:00:00, Read : 732 Times

Jakarta, May 5, 2022

Spokesperson for the Ministry of Health, dr. Siti Nadia Tarmizi, M.Epid revealed that the Government through the Ministry of Health and the DKI Jakarta Health Office conducted contact investigations to determine the risk factors for three cases of acute hepatitis in children. This was conveyed in a press statement in Jakarta (5/5).

''Based on the results of the contact investigation of the cases who died, the three of them came to the health facility in an advanced stage, so they only gave a little time for health workers to take rescue action,'' said dr. Nadia.

In these three cases, children aged 2 years had received hepatitis vaccination, age 8 had received a one-time COVID-19 vaccine and a complete hepatitis vaccine, and an 11-year-old child had received a complete COVID-19 and hepatitis vaccination. All three tested negative for COVID-19. Based on the results of the investigation, it was also found that one case had co-morbidities.

Those who are 2 years old have hepatitis vaccine and 8 (covid 1 time and complete vaccine) and 11 (covid and complete hepatitis).

"Until now, we cannot classify these three cases as acute hepatitis with severe symptoms, but they are included in the pending classification criteria because there are still laboratory tests that must be carried out, especially adenovirus examination and Hepatitis E examination which takes between 10 to 14 days. forward,''said dr. Nadia.

In addition, added dr. Nadia had no history of hepatitis from other family members of the three children. And there were no other family members who had the same symptoms. The main complaint submitted from the gastrointestinal tract, experienced complaints of nausea, vomiting, and severe diarrhea.

This news was broadcast by the Bureau of Communications and Public Services, Ministry of Health of the Republic of Indonesia. For further information, please contact the Halo Ministry of Health hotline number via hotline 1500-567, SMS 081281562620, facsimile (021) 5223002, 52921669, and contact email address [at] Kemkes [dot] go [dot] id (NI)

https://www.kemkes.go.id/article/view/22050500002/pemerintah-lakukan-investigasi-kontak-3-kasus-hepatitis-akut-pada-anak.html

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Minister confirms 15 suspected cases of acute hepatitis in Indonesia

4 hours ago

Jakarta (ANTARA) - The number of suspected cases of acute hepatitis in Indonesia currently reached 15, according to Health Minister Budi Gunadi Sadikin.

"Up until now, Indonesia has registered 15 (suspected) cases. Globally, Britain reported the highest number at 115, (followed by) Italy, Spain, and the United States," Sadikin noted during a virtual press conference streamed on the YouTube channel of the Presidential Secretariat in Jakarta on Monday evening.
...

https://en.antaranews.com/news/228609/minister-confirms-15-suspected-cases-of-acute-hepatitis-in-indonesia

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[Shiloh]

Source: https://www.bloomberg.com/news/artic...s-in-indonesia

Four More Children Die of Acute Hepatitis in Indonesia
By
Soraya Permatasari
May 13, 2022, 4:20 a.m. EDT


Four more children have died in the latest outbreak of acute hepatitis in Indonesia, bringing the country’s total fatalities to seven.

Cases have been found across the Southeast Asian nation, with many of them in the capital Jakarta, said Mohammad Syahril, head of state-run Sulianti Saroso Hospital. The hospital is monitoring one more probable case, among 18 children below 16 years old who were suspected of suffering from the illness....

[Shiloh]

Source: https://www.cnbcindonesia.com/tech/2...itis-mysterius

There are 14 cases, this is how the Ministry of Health stems from mysterious hepatitis
Tech - Intan Rakhmayanti Dewi, CNBC Indonesia
23 May 2022 18:10

Jakarta, CNBC Indonesia - Deputy Minister of Health Dante Saksono revealed that there were 14 cases of acute hepatitis found in the country until May 20, 2022. For this reason, the Ministry of Health has taken steps to stem the disease.

Since the first case in Indonesia was reported on 27 April 2022, the Ministry of Health has directly communicated with the CDC and the UK government to get stories about their experiences.

"We held a video conference with the most skilled experts in the United States and Britain to conduct medical technical talks on the case and from the conclusion they still don't know," said Dante in a working meeting with Commission IX of the Indonesian House of Representatives, Monday (23/5). /2022).

Then, the Ministry of Health also increased public awareness by making a circular letter on vigilance against the discovery of cases of acute hepatitis of unknown etiology (causes).

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[Shiloh]

Source: https://en.tempo.co/read/1594808/ind...cute-hepatitis

Indonesia Logs Two New Suspected Cases of Acute Hepatitis
Translator: Dewi Elvia Muthiariny
Editor: Mahinda Arkyasa
24 May 2022 23:52 WIB

TEMPO.CO, Jakarta - Indonesia recorded two new suspected cases of unknown acute hepatitis in children this week, adding the total number to 16. The two suspected cases were reported in Banten and South Sulawesi.

"So, the total number of the cases in Indonesia is 16, consisting of one probable case and 15 cases classified as pending," said a spokesman for the Health Ministry, Mohammad Syahril, in a virtual press conference, Tuesday afternoon, May 24, 2022.

Syahril, who is also the President Director of the Sulianti Saroso Infectious Diseases Hospital (RSPI Sulianti Saroso) in North Jakarta, said that the two latest cases were classified as pending because they were still waiting for laboratory results for Hepatitis A-E and other pathogens. The other 13 cases came from Jakarta, Yogyakarta, West Sumatra, NTB, Bali, East Java, Jambi, and Bangka Belitung.

Three of the patients in this group had died...