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  • Japanese Encephalitis in India - Multi-state

    I am starting a new thread with this ProMed post. Several other related articles have already been posted in the Acute Encephalitis Syndrome (AES) thread, which is not correct. Perhaps some of those posts should be moved here. AES was caused by an enterovirus during 2008 and was NOT Japanese encephalitis. Also, note that neither virus has anything to do with the country of Japan.



    JAPANESE ENCEPHALITIS - INDIA (02): (UTTAR PRADESH, NAGALAND, ASSAM)
    *************************************
    A ProMED-mail post
    <http://www.promedmail.org>
    ProMED-mail is a program of the
    International Society for Infectious Diseases
    <http://www.isid.org>

    In this update:
    [1] Uttar Pradesh
    [2] Nagaland
    [3] Nagaland, Upper Assam

    ******
    [1] Uttar Pradesh
    Date: Mon 17 Aug 2009
    Source: Indian Express [edited]
    <http://www.indianexpress.com/news/what-about-encephalitis-up-doctor-writes-in-blood-to-rahul/502895/>


    More than 200 cases and 40 deaths have taken place in eastern UP
    [Uttar Pradesh state] in the past one month due to encephalitis, the
    disease which has a mortality rate between 30 to 40 percent. In the
    same period, only 20 cases of mild flu have been reported. According
    to Dr K P Kushwaha of the BRD Medical College, 8-10 patients are
    being admitted daily at BDR Medical College. However, while all
    government attention is focused on swine flu [influenza (H1N1) 2009],
    few seem to be bothered about encephalitis. For swine flu, all
    hospitals have been put on alert, whereas there is no such alert for
    encephalitis. Tests for detection of swine flu, each of which is 3
    times costlier, are being done daily, while encephalitis-detection
    tests are being conducted at a maximum of thrice a week.

    "The reason is simple: swine flu is an imported disease where the
    victims are either people who have returned from abroad or belong to
    the middle class. Encephalitis is affecting children of poor people
    in eastern UP. We have to find ways to draw attention towards
    encephalitis deaths and cases," said Dr R N Singh, who heads
    Encephalitis Eradication Movement, a private initiative.

    [Byline: Maulshree-Seth]

    --
    Communicated by:
    HealthMap Alerts via ProMED-mail
    <promed@promedmail.org>

    [These encephalitis cases are likely due to Japanese encephalitis
    virus (JEV) infections. The state of Uttar Pradesh (UP) is endemic
    for JEV. A report of 9 May 2009 (see ProMED archive number
    20090513.1789) indicated that there were 38 fatalities and 170
    hospitalized encephalitis cases suspected JEV infections in UP. This
    current report above indicates that the hospital receiving the
    patients is doing laboratory tests, but does not indicate if the
    tests are confirming JEV as the etiological agent involved. ProMED
    would appreciate receiving additional information. It would also be
    of interest to know if the national JEV vaccination program has been
    operating in this area this year.

    A map showing the location of Indian states including Uttar Pradesh
    in northeastern India can be accessed at
    <http://www.lib.utexas.edu/maps/middle_east_and_asia/india_pol01.jpg>
    A HealthMap/ProMED-mail interactive map of India can be accessed at
    <http://healthmap.org/promed/en?v=22.9,79.6,5>
    - Mod.TY]

    ******
    [2] Nagaland
    Date: Mon 17 Aug 2009
    Source: New Kerala.com [edited]
    <http://www.newkerala.com/nkfullnews-1-93740.html>


    Japanese encephalitis, a communicable [mosquito transmissible, not
    transmissible from person-to-person - Mod.TY] disease, has entered
    Nagaland and so far 4 cases have been detected throughout the state.
    State Nodal Officer Dr Kevichusa Medikhru here today said samples of
    5 patients were sent for testing, out of which 4 were confirmed to be
    suffering from Japanese encephalitis. The patients were from Dimapur
    and Tuli area of Mokokchung district. The cases were referred to the
    National Vector Borne Control Programme (NVBCP) officials to initiate
    necessary follow up action.

    Japanese encephalitis [virus] is endemic to the state along the
    foothill areas. However, no report of such cases have so far been
    received from other districts of the state.

    --
    Communicated by:
    HealthMap Alerts via ProMED-mail
    <promed@promedmail.org>

    ******
    [3] Nagaland, Upper Assam
    Date: Sat 8 Aug 2009
    Source: Eastern Mirror [edited]
    <http://www.easternmirrornagaland.com/index.php?option=com_content&view=article&id=13640 :japanese-encephalitis-emerging-threat-to-states-health-&catid=61:top-news>


    While the spreading H1NI virus (swine Flu) has been creating jitters
    within the state medical department and the local populace, another
    viral disease -- Japanese encephalitis [JE], also transmitted through
    mosquitoes via pigs [and wild birds. - Mod.TY] -- is posing a more
    immediate threat with 5 confirmed cases of mortality within 2 months.
    The impact of this viral disease here in the state cannot be fully
    gauged at the moment because no survey has been conducted yet.

    The common symptoms of JE [virus infections] are headache, stupor,
    fever, disorientation, coma and paralysis -- loss of co-ordination.
    There is no specific treatment or cure for JE. However, supportive
    treatment and good nursing care can significantly reduce case
    fatality rate. It is, therefore, important that encephalitis cases
    should be referred to a hospital as early as possible, doctors insisted.

    The Japanese encephalitis virus has a complex life cycle involving
    domestic pigs and a specific type of mosquito, _Culex
    tritaeniorhynchus_ [and other closely related _Culex_ species -
    Mod.TY], that lives in rice-growing and pig-farming regions. The
    animal hosts mainly include pigs and amongst birds are the water
    birds, poultry birds and ducks. Pigs are the major vertebrate hosts
    and are considered as amplifying hosts. Infection in man appears to
    be correlated with living in close proximity with animal reservoirs,
    especially pigs. The virus in an infected person invades the central
    nervous system, including the brain and spinal cord, causing brain
    damage, including paralysis and also death.

    Zion Hospital has reported clinically confirmed death of 5 patients
    from around 17 suspected cases. Most of the cases reported till now
    are from various areas in Dimapur including Purana Bazar, Thlixu
    village, Diphupar, Notun Basti, Supply Colony and Ao Kashiram. One
    isolated case from Tenning under Peren district and around 2 from
    Tuli have been reported so far.

    In slight contrast, Dr Neiketou Angami, Joint Director NVBDCP
    informed that 11 cases have been reported. Among the 11 reported
    cases, 4 out of 5 samples sent to National Centre for Infectious
    Disease (NCID) for blood test have been confirmed positive. And 2 of
    the patients who tested positive, have reportedly succumbed. The
    joint director informed that 3 more blood samples, 2 from Referral
    hospital and another from Dimapur Hospital have been sent to NCID for
    blood test. With no proper testing facilities in the state, about one
    week is wasted in sending the samples to Delhi for testing and
    confirming the results.

    Efforts are being made to identify the outbreak areas of the disease
    so that fogging and impregnation of bed-nets would be carried out
    along with sensitization, Dr Imcha, DMO, Malaria department informed.
    Meanwhile, outbreak of JE from Tuli in Mokokchung district has been
    reported, with one confirmed death and 2 other positive cases. 2
    places namely Teyong Mopu at Tzudikong and Longpong ward, Tuli have
    also been identified for protection measures. Residents of Tuli and
    Tzudikong town also expressed suspicion that 3 patients, whose deaths
    were suspected to have been caused by malaria, might actually have
    been infected with JE.

    The state malaria department has alerted all district malaria
    officers with regard to JE and has been in the process of going about
    with control measures like fogging, distributing insecticide treated
    bed-nets, introducing Larvivorous fish in water bodies and
    sensitizing the citizens on the disease.

    It may be mentioned that in 2007, 11 cases of JE were reported with
    one death. During 1985-86, the 1st reported outbreak of JE in
    Nagaland, 50 cases were confirmed with 60 percent mortality (30
    deaths), according to reports.

    Japanese Encephalitis (JE) poses a serious threat in Nagaland,
    particularly with unmonitored rearing of pigs in residential areas.
    And with the late onset of monsoon this year, it would only mean more
    density of mosquitoes and so chances of more cases of JE disease.
    Even in developed towns like Dimapur, pigsties can be found in
    backyards of many homes, in close proximity to living quarters of
    people. Dr Imcha, while stressing that pigs should normally be reared
    5 kilometers away from human inhabitation, said enforcement of such
    laws has been found practically impossible in Nagaland. Added to
    that, the town and municipal councils are yet to wake up from their
    slumber, to monitor rearing of pigs in residential areas.

    Most doctors, when asked about the magnitude of threat posed by JE,
    expressed concern over possibility of many undetected cases,
    particularly with pig-rearing being a common practice among Nagas.
    The only option to battle the spread of the fatal infection, Dr.
    Imcha says, would be to adopt preventive measures as directed by the
    malaria department. And though, National Vector Borne Disease Control
    Programme, Nagaland under malaria department has been making efforts
    to take preventive measures, awareness of the viral disease is found
    to be still lacking among the citizens, with many confusing it for
    malaria or typhoid.

    Officially, 34 people have died of encephalitis in Upper Assam in
    July [2009], according to newspaper reports, while the unofficial
    number has been pegged beyond 50. More than 100 people are now
    battling the disease in hospitals across Upper Assam.

    --
    Communicated by:
    ProMED-mail
    <promed@promedmail.org>

    [These JE reports indicate the need for a well organized and
    integrated prevention, control and treatment approach to JE in areas
    where the virus is endemic. Sentinel pig and _Culex_ mosquito
    monitoring would provide an indication of the time and places where
    transmission is becoming active. This requires rapid laboratory
    support. Ongoing public education reduce mosquito breeding and avoid
    mosquito bites would reduce human cases. Public education is also
    important for timely visits to health centers and hospitals to
    improve early provision of treatment of JE virus infected patients
    and reduce case fatality rates. India has an active JE virus
    vaccination program, and it would be of interest to know its extent
    in Nagaland and Upper Assam. All of these measures require
    considerable financial support, and would compete with other
    important public health programs.

    General information on Japanese encephalitis can be accessed at
    <http://www.who.int/water_sanitation_health/diseases/encephalitis/en/> and
    <http://www.cdc.gov/ncidod/dvbid/jencephalitis/qa.htm> - Mod.TY]

    [The interactive HealthMap/ProMED map for India is available at:
    <http://healthmap.org/r/008o> - CopyEd.EJP]

    [see also:
    Japanese encephalitis - India (UP): susp, RFI 20090513.1789
    2008
    ---
    Japanese encephalitis - India (08): (UP) 20081115.3609
    Japanese encephalitis - India (07): (UP) 20081110.3542
    Japanese encephalitis - India (06): (WB, UP) 20081017.3295
    Japanese encephalitis - India (05): (UP) RFI 20081014.3260
    Japanese encephalitis - India (04): (UP, AS) 20080923.3011
    Japanese encephalitis - India (03): (UP), RFI 20080923.2998
    Japanese encephalitis - India (02): (UP) 20080918.2924
    Japanese encephalitis - India: (UP) 20080731.2345]
    ....................ty/ejp/mpp

  • #2
    Re: Japanese Encephalitis in India - Multi-state

    Other than JE itself, I'm not sure what else they would test positive for. I think this is a misunderstanding and possibly a mistranslation at some point - I think the correct statement should be that 640 people have symptoms of JE, and 30 are lab confirmed.



    Archive Number 20090819.2937
    Published Date 19-AUG-2009
    Subject PRO/AH/EDR> Japanese encephalitis - India (03): (UP) RFI

    JAPANESE ENCEPHALITIS - INDIA (03): (UTTAR PRADESH) REQUEST FOR INFORMATION
    ************************************************** *************************
    A ProMED-mail post
    <http://www.promedmail.org>
    ProMED-mail is a program of the
    International Society for Infectious Diseases
    <http://www.isid.org>

    Date: Tue 18 Aug 2009
    Source: CNN.com [edited]
    <http://edition.cnn.com/2009/HEALTH/08/18/encephalitis.india.outbreak/index.html?iref=mpstoryview>


    Doctors say an encephalitis outbreak has killed 130 people -- mostly
    children -- in northern India since January [2009]. The outbreak of
    acute encephalitis -- an inflammation of brain tissue -- is mostly
    concentrated in eastern parts of Uttar Pradesh, said VS Nigam, the
    state's nodal officer for tackling the disease. He told CNN that 640
    patients had tested positive for the infection, including 30 with
    Japanese encephalitis, which is spread by mosquitoes.

    Acute encephalitis can be spread in various ways, including a
    bacterial or viral infection; the ingesting of toxic substances; and
    complications of a disease.

    The disease has mostly struck children up to 15 years old, Nigam added.

    --
    Communicated by:
    HealthMap Alerts via ProMED-mail
    <promed@promedmail.org>

    [The outbreak of encephalitis in eastern Uttar Pradesh continues to
    grow. The etiology (etiologies?) of the encephalitis outbreak
    reported above is somewhat confusing. Clearly, Japanese encephalitis
    virus is involved in some of these cases. That is not surprising as
    Uttar Pradesh is endemic for Japanese encephalitis virus. The open
    question concerns the remaining 610 patients that were reported as
    "testing positive." Positive for what? ProMED-mail would appreciate
    receiving additional information as it become available.


    A map showing the location of Indian states including Uttar Pradesh
    in northeastern India can be accessed at
    <http://www.lib.utexas.edu/maps/middle_east_and_asia/india_pol01.jpg>.
    A HealthMap/ProMED-mail interactive map of India can be accessed at
    <http://healthmap.org/r/00Hk>. - Mod.TY]

    [see also:
    Japanese encephalitis - India (02): (UP, NL, AS) 20090818.2929
    Japanese encephalitis - India (UP): susp, RFI 20090513.1789
    2008
    ----
    Japanese encephalitis - India (08): (UP) 20081115.3609
    Japanese encephalitis - India (07): (UP) 20081110.3542
    Japanese encephalitis - India (06): (WB, UP) 20081017.3295
    Japanese encephalitis - India (05): (UP) RFI 20081014.3260
    Japanese encephalitis - India (04): (UP, AS) 20080923.3011
    Japanese encephalitis - India (03): (UP), RFI 20080923.2998
    Japanese encephalitis - India (02): (UP) 20080918.2924
    Japanese encephalitis - India: (UP) 20080731.2345]
    ...................................ty/mj/mpp

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